Bio inOhio Facts and Stats 6/2009


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A detailed, fact based PPT about the bioscience industry in Ohio

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  • Consider: Leis Medical Inc. founded by Arthur F. Leis in Dayton, Ohio in 1950. They have grown from a single person entrepreneurship to encompass a 71,000 square foot plant employing the latest in computer-controlled tool and manufacturing systems. 3 years ago they made a complete conversion from an auto industry supplier to 100% medical company. Beginning as a design and engineering service, we followed the natural progression of growth through tool, die and special machinery into today’s more exacting area of contract machining. We have established a premier reputation as a company to be counted on when the job is difficult and must be done accurately.
  • Seven (7) Edison Technology Centers located around the state provide a variety of product and process innovation and commercialization services to both established and early-stage technology-based businesses  such as:  new product design; CAD/CAM; prototyping; materials selection and handling; plant layout and design; quality systems; information systems; machining; joining technology assistance; and biotechnology business consulting.  (See synopsis of each Center below.) MAGNET - Cleveland, Ohio:   Regional center focused on manufacturers; 2. Edison Materials Technology Center - Dayton, Ohio:  Statewide organization focused on advanced materials and materials processing including all traditional metals, all forms of composites, rubber, biomaterials, PEM and Solid Oxide Fuel Cells, and nanomaterials; 3. Edison Welding Institute - Columbus, Ohio:  Membership-based organization; internationally recognized institution focused on materials joining technology; 4. EISC - Toledo, Ohio:  Statewide center focused on food technology, particularly in processing/packaging (e.g., blow molding and wrap technology). 5. Ohio's IT Alliance - Columbus, Ohio:  Statewide organization focused on developing the IT industry in Ohio; 6. BioOhio - Columbus, Ohio:  Statewide center focused on promoting bio-life sciences industry in Ohio, including pharmaceutical and medical device development; 7.  TechSolve   - Cincinnati, Ohio:  Regional center focused on manufacturers; provides advanced manufacturing process and system services and productivity improvement training; nationally recognized center in machining technology;
  • Consider
  • Golden Rice Herbicide-resistant and insecticidal plants make great sense for farmers. BT corn, resistant to borers, saved just under 2000 tons in 2001, and used 8 million pounds less pesticides. Pest-resistant soybeans saved farmers $1 billion by reducing pesticide use by 28 million pounds. In Alabama, cotton losses to insects aren’t 50% like they were in 1995, they’re now 2% to 7% Biotech corn was 34% of seed corn planted in 2002 75% of American soybean acres were planted in biotech seeds in 2002. They were first planted in 1996.
  • Bio inOhio Facts and Stats 6/2009

    1. 1. BioOhio Update John F. Lewis Jr. 6-18-09 An Ohio Thomas Edison Center
    2. 2. <ul><li>hallo </li></ul><ul><li>bonjour </li></ul><ul><li>shalom </li></ul><ul><li>konnichiwa </li></ul><ul><li>Nihao </li></ul><ul><li>Anyohaseo </li></ul><ul><li>päivää </li></ul><ul><li>Fáilte </li></ul><ul><li>Hola </li></ul>
    3. 3. Ohio, more than you know… <ul><li>7th largest state with 11.5 million people </li></ul><ul><li>4 th in the nation for biotech Industry strength </li></ul><ul><li>Within 1 day drive of 61% of USA, 50% Canada </li></ul><ul><li>Highly educated workforce </li></ul><ul><li>> 150 colleges and universities </li></ul>
    4. 4. Ohio More than you know… <ul><li>7th largest state with 11.5 million people </li></ul><ul><li>4 th in the nation for biotech Industry strength </li></ul><ul><li>Within 1 day drive of 61% of USA, 50% Canada </li></ul><ul><li>Highly educated workforce </li></ul><ul><li>> 150 colleges and universities </li></ul>
    5. 5. The Original Biotechnologies
    6. 6. What is Bioscience? <ul><ul><li>… a broad sector, including: </li></ul></ul><ul><ul><li>Pharmaceuticals </li></ul></ul><ul><ul><li>Genomics </li></ul></ul><ul><ul><li>Diagnostics </li></ul></ul><ul><ul><li>Medical devices & equipment </li></ul></ul><ul><ul><li>Bioinformatics </li></ul></ul><ul><ul><li>Biomedical imaging </li></ul></ul><ul><ul><li>Biomaterials </li></ul></ul><ul><ul><li>Clinical Research Organizations </li></ul></ul><ul><ul><li>Environmental </li></ul></ul><ul><ul><li>Regenerative medicine </li></ul></ul><ul><ul><li>Research and development & Testing Labs </li></ul></ul><ul><ul><li>Agricultural bioproducts </li></ul></ul><ul><ul><li>Healthcare Informatics </li></ul></ul><ul><ul><li>Nutraceutical/Food </li></ul></ul>
    7. 7. Bioscience Subsectors Agricultural Feedstock & Chemicals <ul><li>Agricultural processing </li></ul><ul><li>Basic organic chemicals </li></ul><ul><li>Ethyl alcohol mfg. </li></ul><ul><li>Organic fiber mfg. </li></ul><ul><li>Fertilizers </li></ul><ul><li>Pesticides and other agricultural chemicals </li></ul><ul><li>Medicinal & botanicals </li></ul><ul><li>Pharma- ceutical preparations </li></ul><ul><li>Diagnostic substances </li></ul><ul><li>Biological products </li></ul>Drugs & Pharmaceuticals Medical Devices & Equipment <ul><li>Laboratory apparatus & furniture </li></ul><ul><li>Surgical, medical, dental, ophthalmic & analytical instruments & equipment </li></ul><ul><li>Irradiation apparatus & electromedical equipment </li></ul>Hospitals <ul><li>Specialty hospitals </li></ul><ul><li>University medical research hospitals </li></ul><ul><li>Clinical research institutions </li></ul>Research, Testing, & Medical Laboratories <ul><li>Biological research </li></ul><ul><li>Commercial medical research </li></ul><ul><li>Testing laboratories </li></ul><ul><li>Medical laboratories & diagnostic imaging centers </li></ul>Product-Oriented Service -Oriented
    8. 8. Why Listen to me? <ul><li>We want to give you > business, help create regional jobs, give you all > visibility, > bio linkages with rest of the state, more wins </li></ul><ul><ul><li>but we need your help!!! </li></ul></ul><ul><li>Licensed attorney in Ohio 1987 </li></ul><ul><li>18 years international and TBED experience </li></ul><ul><li>Lived in 3 countries, traveled to >50 </li></ul><ul><ul><li>VC in Caribbean, Medical/Pharma/Opto Asia </li></ul></ul><ul><li>Started offices, JV’s in Korea & China, closed one in PRC </li></ul><ul><li>Since 2001 been with BioOhio </li></ul><ul><ul><li>Helped raised more than $1 billion </li></ul></ul>
    9. 9. Our History <ul><li>1987 Edison BioTechnology Center (EBTC) </li></ul><ul><li>2001 Moved HQS to Columbus </li></ul><ul><li>2002 Omeris </li></ul><ul><li>2007 BioOhio </li></ul>
    10. 10. Our History <ul><li>Founded in 1987 as the Edison BioTechnology Center , BioOhio (formerly Omeris ) is a non-profit organization designed to build and accelerate bioscience industry, research, and education in Ohio </li></ul><ul><li>Headquartered in Columbus, with affiliates around the state </li></ul>
    11. 11. Be Proud…Be Strategic “ Ohio is one of the best places in the world to optimize the growth of your bioscience company because we can imbed you in an asset base, 1141 companies and growing; We are a partner that allows you to maximize any or all phases of your business strategy”
    12. 12. * Total Ohio bioscience establishments are 1141 (March 1, 2009)
    13. 14. Large Ohio Bioscience Companies <ul><li>Procter & Gamble Pharmaceuticals </li></ul><ul><li> </li></ul><ul><li>Ethicon Endo-Surgery (J&J) </li></ul><ul><ul><li> </li></ul></ul><ul><li>Cardinal Health </li></ul><ul><ul><li> </li></ul></ul><ul><li>Battelle Memorial Institute </li></ul><ul><li> </li></ul><ul><li>STERIS </li></ul><ul><ul><li> </li></ul></ul><ul><li>Philips Medical Systems </li></ul><ul><ul><li> </li></ul></ul><ul><li>Abbott Nutrition (Ross Laboratories) </li></ul><ul><li> </li></ul><ul><li>Chemical Abstracts </li></ul><ul><ul><li> </li></ul></ul><ul><li>Mettler-Toledo </li></ul><ul><ul><li> </li></ul></ul><ul><li>Invacare </li></ul><ul><ul><li> </li></ul></ul>… and lots of emerging and mid sized companies
    14. 16. 3 cities in the top 40 Biotech locations in USA #4 in biotechnology industry strength 2008 All three cities rank higher than the 100 city average in Research grant awards in Bio- Sciences $637 Million in NIH Awards in 2008! State City Rank OH Cleveland-Akron 20 Columbus 22 Cincinnati 28
    15. 23. Direct Commercial Bioscience Economic Impact Summary
    16. 24. Central Ohio Regional Impact
    17. 25. Northeast Ohio Regional Impact
    18. 26. Southwest Ohio Regional Impact
    19. 27. West Central Ohio Regional Impact
    20. 28. Southeast Ohio Regional Impact
    21. 29. Northwest Ohio Regional Impact
    22. 32. Total Bioscience Funding 2004-2007
    23. 34. Top Employers
    24. 35. Top Employers
    25. 36. Top Employers
    26. 37. NAICS
    27. 38. NAICS
    28. 39. Ohio is ranked 8 th nationally in total patents issued and has more than every country in the world except for Japan, Germany, and the UK
    29. 40. Fantastic Hospitals <ul><li>2008 US News and World Report found 14 top hospitals in Ohio </li></ul><ul><ul><li>Cleveland Clinic 4 th best hospital in the nation and Top Heart Center in the country for 14 straight years </li></ul></ul><ul><ul><li>Rainbow Babies Children’s Hospital (Cleveland) 2 nd in neonatal care </li></ul></ul><ul><ul><li>4 pediatric hospitals ranked in the Top 15 </li></ul></ul><ul><ul><li>6 of the top 50 Endocrinology Centers, most in the nation </li></ul></ul><ul><ul><li>6 top 50 Orthopedic centers </li></ul></ul><ul><ul><li>3 top 50 adult cancer centers, </li></ul></ul><ul><li>Child Magazine ranked Nationwide Children’s Hospital (Columbus) as the #1 facility for pediatric emergency care in 2007 </li></ul><ul><li>Thomson Reuters National Top 100, which measures hospital reliability, ranked 10 Ohio hospitals, second most in the nation in 2008 </li></ul><ul><ul><li>Most ranked facilities in the nation over the last five years </li></ul></ul>
    30. 42. 16% of all clinical trials in the US are conducted in Ohio
    31. 43. Distribution of Active Clinical Trials by Disease As of June 2009
    32. 44. <ul><li>Now 63 Ohio Health Care Venture Funds…More than 100 have invested into Ohio bioscience companies </li></ul><ul><li>Adena Ventures </li></ul><ul><li>Akron ArchAngels Network </li></ul><ul><li>Alpha Capital Partners </li></ul><ul><li>Arboretum Ventures </li></ul><ul><li>Athenian Ventures </li></ul><ul><li>Battelle Ventures </li></ul><ul><li>Blue Chip Venture Company </li></ul><ul><li>Blue Point Capital </li></ul><ul><li>Bridge Investment Fund </li></ul><ul><li>Case Technology Ventures </li></ul><ul><li>Charter Life Sciences </li></ul><ul><li>Chrysalis Ventures </li></ul><ul><li>CID Equity Partners </li></ul><ul><li>Cincinnati Children's Tomorrow Fund </li></ul><ul><li>CincyTech Ventures </li></ul><ul><li>Cleveland Clinic Innovations </li></ul><ul><li>Core Network </li></ul><ul><li>Draper Triangle Ventures </li></ul><ul><li>Early Stage Partners </li></ul><ul><li>Edgewater Capital </li></ul><ul><li>Entrepreneurs “E” Fund </li></ul><ul><li>Everett Partners </li></ul><ul><li>Fletecher Spaght </li></ul><ul><li>Fort Washington Capital </li></ul><ul><li>Foundation Medical Partners </li></ul><ul><li>Frantz Medical Ventures </li></ul><ul><li>Glengary Ventures </li></ul><ul><li>GLIDE Fund </li></ul><ul><li>iNetwork BioOpportunity </li></ul><ul><li>Innovation Fund of LCCC </li></ul><ul><li>Isabella Capital </li></ul><ul><li>JumpStart </li></ul><ul><li>Kadima Partners </li></ul><ul><li>Miami Valley Ventures </li></ul><ul><li>Morgenthaler Ventures </li></ul><ul><li>Mutual Capital </li></ul><ul><li>NCIC Capital </li></ul><ul><li>NCT Ventures </li></ul><ul><li>North Coast Angels </li></ul><ul><li>Oakwood Medical </li></ul><ul><li>Ohio Tech Angels I, II & III </li></ul><ul><li>Portal Capital </li></ul><ul><li>Primus Capital </li></ul><ul><li>Queen City Angels </li></ul><ul><li>Radius Ventures </li></ul><ul><li>Redwood Holdings </li></ul><ul><li>Reservoir Ventures </li></ul><ul><li>River Cities Capital Funds </li></ul><ul><li>Riverside Capital </li></ul><ul><li>Rivervest Capital </li></ul><ul><li>Soin International </li></ul><ul><li>RMS Investments </li></ul><ul><li>Rocket Ventures </li></ul><ul><li>Southern Ohio Creates Capital </li></ul><ul><li>Summit Health Ventures </li></ul><ul><li>Sycamore Partners </li></ul><ul><li>Talisman Capital </li></ul><ul><li>TechColumbus TechGenesis </li></ul><ul><li>TechColumbus RCF </li></ul><ul><li>Teton Capital </li></ul><ul><li>Triathlon Medical Ventures </li></ul>
    33. 45. Business Climate Improved <ul><li>Jobs and Progress Plan </li></ul><ul><li>10-year, $5 billion investment in Ohio’s highways </li></ul><ul><li>Tax Reform </li></ul><ul><ul><li>21 percent income tax reduction </li></ul></ul><ul><ul><li>Eliminating property taxes on investments in machinery and equipment </li></ul></ul><ul><ul><li>No business tax on products exported out of Ohio </li></ul></ul><ul><ul><li>First $1 million of gross receipts tax-free </li></ul></ul><ul><li>Lawsuit Reform </li></ul><ul><li>Third Frontier $1.6 billion </li></ul><ul><li>Ohio’s Bipartisan Jobs Stimulus Plan $1.57 billion </li></ul><ul><ul><li>($100 million, $50 million, $250 million) </li></ul></ul>
    34. 46. Tax Reform
    35. 47. <ul><li>Cardiovascular </li></ul><ul><li>BioPharma </li></ul><ul><li>BioPolymers </li></ul><ul><li>Biomedical Imaging </li></ul><ul><li>AgBio </li></ul>
    36. 48. Ohio Ranks 4 th in the Nation in Biotech Strength in the latest report
    37. 49. Ohio – National Top 10 AdvaMed
    38. 50. Ohio claims its 3 rd Governor's Cup in a row, 06-08, for the most new or expanded capital projects, thanks to the Strickland Administration's focus on taking steps necessary to be competitive, even in a challenging economic environment
    39. 51. BioOhio’s Balanced Strategy industry growth, resource optimization, community building Company & Capital Formation Company Attraction & Expansion Member / Trade Association Industry Function Bioscience Workforce & Education
    40. 52. BioOhio Strategic Elements <ul><li>Industry Function: </li></ul><ul><ul><li>Membership </li></ul></ul><ul><ul><li>Fact Sourcing </li></ul></ul><ul><ul><li>Networking </li></ul></ul><ul><ul><li>Branding </li></ul></ul><ul><ul><li>Advocacy </li></ul></ul><ul><li>Asset-based Company Attraction & Expansion </li></ul><ul><li>Workforce & Education </li></ul><ul><li>Company & Capital Formation </li></ul>
    41. 53. BioOhio Statewide Board <ul><li>John A Bantle, II , PhD, Vice President - Research, Wright State University </li></ul><ul><li>Timothy G. Biro , CEO - MORK Process; Partner, Ohio Innovation Fund & Reservoir Ventures </li></ul><ul><li>Greg Blackmore, Sr. Vice President and Group President, Life Sciences - STERIS </li></ul><ul><li>Rathindra Bose, PhD, Vice President for Research & Creative Activity - Ohio University </li></ul><ul><li>Mark A. Collar , Chairman - Third Frontier Advisory Board </li></ul><ul><li>Mark J. Coticchia, VP Research and Technology Management - Case Western Reserve </li></ul><ul><li>Sandra J. Degen , PhD, Vice President for Research - University of Cincinnati </li></ul><ul><li>Anthony J. Dennis, PhD, President & CEO - BioOhio </li></ul><ul><li>Paul DiCorletto, Chairman - Lerner Research Institute (Cleveland Clinic) </li></ul><ul><li>Kevin Driscoll, PhD , Exec Director, Global Health Care Connect & Develop-Procter & Gamble </li></ul><ul><li>John Fisher, Executive Vice President - Ohio Farm Bureau Federation </li></ul><ul><li>Mike Hooven , President & CEO - Enable Medical Technologies </li></ul><ul><li>Peter G. Kleinhenz , General Partner - CID Equity Partners </li></ul><ul><li>Barbara Kunz, President - Health & Life Science Global Division Battelle </li></ul><ul><li>Thomas J. Murphy, President & COO - Ben Venue Laboratories </li></ul><ul><li>John M. Rice , PhD, Managing Partner - Triathlon Medical Ventures </li></ul><ul><li>David R. Scholl , PhD, President & CEO - Diagnostic Hybrids </li></ul><ul><li>James A. Scozzie , PhD, Senior Vice President - BioEnterprise </li></ul><ul><li>Arnold W. Strauss, MD, Director - Cincinnati Children’s Research Foundation </li></ul><ul><li>Caroline Whitacre, PhD, Senior Vice President for Research - The Ohio State University </li></ul>
    42. 54. By-The Numbers, then & now Year 1991 2001 2008/2009 Number of bio entities in Ohio 170 352 1141 (3.2X) 2009 University R&D expenditures $285 million $481 million $1.1 billion (2.3X) New Company starts ≈ 12 12 69 per year (5.8X) 2004-08 Private capital raised for new starts Unknown $14 million $189 million (13.5X) $473 million IPO/Acquisitions 2008 Bioscience Capital sources (in State) 4 8 63 (7.9) 2009 BioOhio (EBTC) membership 52 86 280 (3.3X) 2009
    43. 55. Your Member Organization Your Trade Association / Your Bioscience Chamber <ul><li>Marketing Ohio’s Collaboration & Partnership Opportunities </li></ul><ul><ul><ul><li>New Website launched July 2008 </li></ul></ul></ul><ul><ul><ul><li>Trade Missions (Japan, Taiwan, China, USA, Germany, Israel) </li></ul></ul></ul><ul><ul><ul><li>Various Publications </li></ul></ul></ul><ul><ul><ul><li>LinkedIn </li></ul></ul></ul><ul><ul><ul><li>News Ticker, Webinars, Newsletters and much more </li></ul></ul></ul><ul><li>Networking </li></ul><ul><ul><ul><li>BioOhio </li></ul></ul></ul><ul><ul><ul><li>BIO Mid America Venture Forum </li></ul></ul></ul><ul><ul><ul><li>PhRMA events </li></ul></ul></ul><ul><ul><ul><li>AdvaMed events </li></ul></ul></ul><ul><ul><ul><li>AgBio events </li></ul></ul></ul><ul><ul><ul><li>National BIO events </li></ul></ul></ul><ul><ul><ul><li>Regional Affiliate events </li></ul></ul></ul><ul><li>Advocacy ( National & Ohio) </li></ul><ul><ul><ul><li>SBIR Legislation, Patent Reform </li></ul></ul></ul><ul><ul><ul><li>Drug Pricing and importation </li></ul></ul></ul><ul><ul><ul><li>Stem cell research / Human Cloning </li></ul></ul></ul><ul><ul><ul><li>Bioscience workforce training </li></ul></ul></ul><ul><ul><ul><li>Third Frontier funding strategies </li></ul></ul></ul>
    44. 56. Ohio Bioscience Growth Report & Magazines
    45. 57. Company & Capital Formation <ul><ul><li> </li></ul></ul>
    46. 58. What do our Incubators / Accelerators do? <ul><li>Collaborations with universities, established companies, and start-up companies; national and international collaborations </li></ul><ul><li>Business development to help established and startup companies make contacts and pursue success </li></ul><ul><li>Management support for startup companies, “portable executives,” “entrepreneurs in residence” until the company operates on its own </li></ul><ul><li>Professional Services referrals to attorneys, accountants, regulatory expertise and others who understand the technology, the startup company environment, international business </li></ul><ul><li>Access to Capital helping startups find investors, and helping investors find companies to invest in </li></ul>
    47. 59. Attraction & Expansion <ul><li>Regional Partners – more than 50 </li></ul><ul><ul><li>Monthly phone calls and e-mail updates </li></ul></ul><ul><li>Program Operations </li></ul><ul><ul><li>Finished an attraction brochure </li></ul></ul><ul><ul><li>Workforce/Talent recruitment remains #1 issue </li></ul></ul><ul><li>Global Cardiovascular Innovation Center (GCIC) </li></ul><ul><ul><li>Relationship and Partnership growing and functioning well </li></ul></ul><ul><ul><li>Supply Chain directory </li></ul></ul><ul><li>Expansions </li></ul><ul><ul><li>Site Selection Magazine “Governor’s Cup” 3 years in a row </li></ul></ul><ul><ul><li>Area Development Magazine Silver Shovel Award </li></ul></ul><ul><ul><li>112 Bioscience expansions or new facilities 06-08 </li></ul></ul><ul><li>OEDA/TeamOhio relationship </li></ul><ul><li>Israel, Taiwan, Finland, Ireland, Hungary, China, Germany </li></ul>
    48. 60. Workforce & Education <ul><li>Community College Partnerships. Coordinating the efforts of Ohio’s 2 year college’s to provide comprehensive programs in support of bioscience industry expansion, e.g. introduction of manufacturing content </li></ul><ul><li>Proposals Submitted. Submitted NSF & DOL proposals seeking additional funding in support of biomanufacturing industry expansion </li></ul><ul><li>Blue Ribbon Panel. Invited participant on national 50 member NSF panel to set standards for education bio-technicians. Report published August 2008; </li></ul><ul><li>Career Fairs. Held 3 rd annual Ohio Bioscience Career Fair in November 2008, and rolling out regional events during 2009 </li></ul><ul><li>Job awareness & Community Outreach. Entered into partnership with the Society for Manufacturing Engineers Educational Foundation to address improving bio-manufacturing image </li></ul>
    49. 61. Workforce & Education <ul><li>In Progress & Planned </li></ul><ul><li>Proposals. </li></ul><ul><ul><li>Will submit BioOhio led NSF-ATE proposal, and partner in Lakeland CC led NSF-ATE proposal focused on outreach and awareness in northeast Ohio. </li></ul></ul><ul><ul><li>Engage consulting group to secure additional federal funds </li></ul></ul><ul><ul><li>Continue to push proposal to develop a comprehensive workforce strategy for Bio in Ohio </li></ul></ul><ul><li>Job Awareness & Community Outreach . Work with SME Educational Foundation and others (Indianapolis WIB, MichBio) to implement a comprehensive plan for Ohio/Indiana/Michigan then expand to midwest, and possibly nationally </li></ul><ul><li>Career Fairs. Hold annual Ohio Bioscience Career Fair, and support/initiate others. Lakeland CC will hold NE Ohio bioscience career fair November 5, sponsored by BioOhio. </li></ul><ul><li>Community College Partnerships. Continue to enhance and roll out bioscience workforce support program in partnership with OBOR </li></ul><ul><li>Strategy. Continue working with State (OBOR, ODOD, ODE) to develop comprehensive biosciences “Industry Sector” workforce strategy </li></ul>
    50. 62. Bioscience Jobs <ul><li>Research & Testing 20,565 companies </li></ul><ul><li>Medical Devices 15,190 companies </li></ul><ul><li>Drugs & Pharmaceuticals 2,589 companies </li></ul><ul><li>Ag Feedstock & Chemicals 2,111 companies </li></ul>Distribution of Bioscience Employment by Subsector Source: Battelle calculations based on Bureau of Labor Statistics, QCEW program data from the Minnesota Implan Group. Data include Puerto Rico. Agricultural Feedstock & Chemicals Drugs & Pharmaceuticals Medical Devices & Equipment Research, Testing, & Medical Laboratories
    51. 63. Bioscience Wage Trends <ul><li>The biosciences offer high-paying, quality jobs across a range of occupations </li></ul><ul><li>Bioscience workers earn $26,772 more than the average U.S. private sector wage, with all four subsectors above the national average </li></ul><ul><li>Since 2001, real (inflation-adjusted) earnings are up 6.4% for bioscience workers, compared to just a 1.4% increase for private sector </li></ul>
    52. 64. AgBio <ul><li>Ohio is home to the world’s largest soup factory (Campbell’s) </li></ul><ul><li>Ohio is home to the world’s largest ketchup factory (Heinz) </li></ul><ul><li>Ohio is home to the world’s largest pizza plant (Pillsbury) </li></ul><ul><li>Ohio is home to the world’s largest yogurt plant (Dannon) </li></ul><ul><li>Ohio is home to the country’s largest fructose plant (Cargill) </li></ul><ul><li>More Swiss cheese is produced in Ohio than in Wisconsin </li></ul><ul><li>Center for Innovative Food Technology </li></ul><ul><li>935 food processing facilities </li></ul><ul><li>Ohio Agricultural Research & Development Center </li></ul>
    53. 65. Ohio’s Agricultural Output $79.6 Billion Ohio’s Chemicals, Plastics, Rubber Materials Output $49 Billion Ohio BioProducts Innovation Center                        
    54. 66. Ohio BioProducts Innovation Center Bio-Polymers and Bio-Product System Solutions Bio-Derived Feedstocks Monomers and Resins <ul><li>Soybean Oils </li></ul><ul><li>Next Gen Soybean Oils </li></ul><ul><li>Soy Proteins </li></ul><ul><li>Corn based carbohydrates/sugars </li></ul><ul><li>Polyacids </li></ul><ul><li>Polyols </li></ul><ul><li>Monomers </li></ul><ul><li>Oligomers and Resins </li></ul><ul><li>Specialty Compounds </li></ul><ul><li>Coatings, Binders, Toners </li></ul><ul><li>Adhesives and Sealants </li></ul><ul><li>Composites </li></ul><ul><li>Solvents, Plasticizers </li></ul><ul><li>Lubricants </li></ul><ul><li>Surfactants, Cleaners </li></ul><ul><li>Fertilizer Systems </li></ul>
    55. 67. Impact of the Human Genome Project
    56. 68. Bio-Informatics <ul><li>Genechips (shown) </li></ul><ul><li>Genetic Databases </li></ul><ul><li>Tissue Databases </li></ul><ul><li> </li></ul><ul><li> </li></ul>
    57. 69. <ul><li>Carbon Nanotube </li></ul>Nanotechnology / BioMEMS
    58. 70. Human/Computer <ul><li>Implantable Biochips </li></ul><ul><li>Glucose monitoring </li></ul><ul><li>Identification </li></ul><ul><li>Retinal implant (shown) </li></ul>
    59. 71. 3-D Bioreactor - Mass Production of Embryonic Stem <ul><li>Problem : </li></ul><ul><li>Limited ES cell lines and supplies for regenerative medicine and other biomedical applications </li></ul><ul><li>Solution : in vitro expansion </li></ul><ul><li>2-D Cell culture: labor intensive (frequent sub culturing) and expensive (growth factors; surface coating) </li></ul><ul><li>Need : Better and cheaper 3-D culturing method in bioreactor with controlled environment </li></ul>
    60. 72. Genetically Modified Organisms <ul><li>Opportunity </li></ul><ul><ul><li>Improved pest and disease resistance </li></ul></ul><ul><ul><li>Better economics </li></ul></ul><ul><ul><li>Less use of chemicals Challenge </li></ul></ul><ul><li>Challenges </li></ul><ul><ul><li>Fear of the unknown </li></ul></ul><ul><ul><li>Misunderstanding </li></ul></ul><ul><ul><li>Scientists not attending to social issues </li></ul></ul>
    61. 73. Third Frontier Network (OSCnet) The most advanced IT research network in USA
    62. 74. Sources of Capital <ul><li>Bootstrapping </li></ul><ul><ul><li>Who will benefit from your success? </li></ul></ul><ul><li>FF&F </li></ul><ul><ul><li>Find enthusiastic supporters in your personal network </li></ul></ul><ul><ul><li>Put your own money in (investors want to see this commitment) </li></ul></ul><ul><li>Angels </li></ul><ul><ul><li>Looking to make money, but also hope to get involved and add value </li></ul></ul><ul><li>Grants </li></ul><ul><ul><li>Lots of free and cheap money out there </li></ul></ul><ul><li>Venture / Private Equity </li></ul><ul><ul><li>Care about making a return on investment </li></ul></ul><ul><ul><li>Often do not have time or ambition to get to involved </li></ul></ul><ul><li>SBA / Banks </li></ul><ul><ul><li>Always take debt before equity, but often difficult as they require security (receivables, assets…) </li></ul></ul>
    63. 75. Pitching <ul><li>10 slides, 20 minutes, 30 Point font </li></ul><ul><li>Differentiate for different audiences </li></ul><ul><li>Investor </li></ul><ul><li>Sales Prospect </li></ul><ul><li>Partner Prospect </li></ul><ul><li>B to B </li></ul><ul><li>Problem </li></ul><ul><li>Solution </li></ul><ul><li>Business Model </li></ul><ul><li>Your Magic </li></ul><ul><li>Mktg/Sales </li></ul><ul><li>Competition </li></ul><ul><li>Mgmt Team </li></ul><ul><li>Financial Projections </li></ul><ul><li>Current Status – The Ask </li></ul>
    64. 76. Let me know how we can help you! John F. Lewis Jr. Vice President [email_address] 614-675-3686 x7 An Ohio Thomas Edison Center