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  • While walking thru the streets I see many bald people. My dad is turning bald as well I searched for information about baldness founding that it might be a relation between baldness and heart disease. That’s hat motivates me to do this review
  • Refers to any type of hair loss. Commonly known as baldnessOcurrs when the hair follicle shrinks over time turns into a shorter and finer hair and eventually the follicle don’t grow any new hair
  • Areata some areas or patchesTotalis total hair loss of the scalpUniversalis total hair loss throughout the bodyBarbae loss of facial hairMucinosainlfmatory condition of hair follicle and sebaceous gland
  • Also known as male pattern baldnessHair gradually thins out, usually start with a receding hariline and/or hairloss on the top of the head
  • And compare the pattern with typical pattern2. Evaluate hairscalp using videodermoscopyFinasteride: prevent testosterone converting to dihydrostestosteroneMinoxidil: help hair regrowsPhototherapy treat hereditary hair lossGel: estimulate hair follicle with a protein creating new hair
  • Choose the best match
  • Studies are very few
  • Gretel

    1. 1. Androgenetic Alopecia andCardiovascular Risk Factors Gretel S. Montañez RISE Program- Fall 2011
    2. 2.  What is alopecia?(Nordqvist, 2009) ( Mosby, 2009) Illustration copyright 2000 by Nucleus Communications, Inc. All rights reserved.
    3. 3.  Types of alopecia  Areata  Totalis  Universalis  Barbae  Mucinosa  Androgenetic(Nordqvist, 2007) Illustration (Breeling, 2008)
    4. 4. What is Androgenetic Alopecia?(Nordqvist, 2007) (Berman, Zieve, 2011)
    5. 5.  Diagnosis  Treatments  Eliminating other  Finasteride causes of baldness  Minoxidil  Trichonoscopy  Laser phototherapy  Biopsy  Dermabrasion gel(Nordqvist, 2007)
    6. 6.  Baldness could be a signal of other diseases  prostatic cancer  heart problems  emotional problems  Relations between baldness and cardiovascular risk factors(Arias, 2009)
    7. 7. risk factors in men and women: A comparative study Present the relations between the androgenic alopecia and cardiovascular risk factors Objectives: analyze the presence of cardiovascular risk factors and find the cardiovascular risk in Adult Panel III for metabolic factors, hormonal factors  Comparison between genres Use 154 Caucasian participants, 77 early-onset AGA and 77 healthy controls Results: diagnosed metabolic syndrome in 60% males and 48.6% woman with AGA(Arias, Gutiérrez, Castellote, Buendía, Naranjo, 2009)
    8. 8.  Results:  Diagnosed metabolic syndrome in 60% males and 48.6% woman with AGA  Caroticatheroma plaques in 29.9% in patients with AGA and 7.8% in the control group  High levels of aldosterone and insulin in males and woman with AGA  Conclusion:  Using ultrasound would be useful to find methods to detect cardiovascular risks with early-onset AGA and find an early preventive treatment(Arias, Gutiérrez, Castellote, Buendía, Naranjo, 2009)
    9. 9. Baldness and coronary heart disease risk factors Study the relation between the prevalence of baldness and coronary risks factors in male workers 3 periods of examination (1987-1980) Participants: 872 males  280 fronto-occipital baldness  273 frontal baldness  231 no baldness MAHADEVIA, 2011(Trevisan, Farinaro, Krogh, Joss, Giumfxti, Fusco, Panico, Mellone, Frascatore, Scottoni, Mancini , 1993)
    10. 10.  Method  Make a personal profile that include  Resting electrocardiogram  Blood pressure measurement  Height and weight measurements  Blood sample for cholesterol and triglycerides Results:  38% participants not present signs of hair loss  31.3% had slow frontal baldness  31.9% had fronto-occipital baldness  Baldness was associated with high levels of cholesterol and blood pressure(Trevisan, Farinaro, Krogh, Joss, Giumfxti, Fusco, Panico, Mellone, Frascatore, Scottoni, Mancini , 1993)
    11. 11. The Atherosclerosis Risk in Communities Study Examined the associations between baldness and myocardial infarction and the risk of atherosclerosis Method:  Blood sample took from National Heart Lung  Two groups: Experimental= risk of atherosclerosis and Control= free baldness  Classified the baldness by the Hamilton/Norwood scale  Technician observed the patient head from side and top and compared with normal hair  Organized in 5 groups  No baldness moderate vertex baldness  Frontal baldness alone severe vertex baldness  Mild vertex baldness(Shahar, Heiss, Rosamond, Szklo et al , 2007) skip
    12. 12. back2008 DermaGenoma Inc, all rights reserved.
    13. 13.  Method (cont.)  Distribution of baldness pattern by myocardial infarction status and the relations of baldness in several risk factors for coronary heart disease.  The relations of baldness patterns in a carotid thickness  The subject were 5,056 men (52-75 years)  767 had history of myocardial infarctions  Results:  .28 (frontal baldness),  1.02 (mild vertex baldness)  1.40 (moderate vertex baldness)  1.18 (severe vertex baldness)  Baldness patterns were not an important risk factor for myocardial infarction or atherosclerosis(Shahar, Heiss, Rosamond, Szklo et al , 2007)
    14. 14. Discussion First study  Confirms the association between early-onset Androgenetic alopecia and a higher cardiovascular risk  Prevalence of carotid atheromatosis in patients with AGA Second study  Pattern of male baldness were associated with increased levels of serum total cholesterol and high blood pressure Third study  No evidence of an association between baldness and carotid thickness
    15. 15. Conclusion 2/3 studies reviewed sustain my statement Contributions to science  Lead to future studies about the relations of alopecia with other diseases  Informs society