1. ProfessorYuka Itokawa ， ProfessorYeunhwa GU Prepared by: Japan Suzuka University of Medical Science 30P1-am238 Register #

9. SOD-like activity (after 15th) This histograph is the image of SOD （ 15days later ） . Each histograph represents the mean value ±SE. SOD-like activity (after 15th)

10. SOD-like activity (after 30th) This histograph is the image of SOD （ 30days later ） .Each histograph represents the mean value ±SE. Analyzed by Dunett-test SOD-like activity (after 30th) *

11. leukocytes This change in number of leukocytes the blood took from the tail vein ICR mice. Each line gram represents the mean value ±SE. Analyzed by Fisher-test. *p<0.05,**p<0.01 vs control. （↑ 2Gy whole body irradiation ） * ** ** ** * * * * * * Gu Lab

12. This change in number of ｌ ymphocyte the blood took from the tail vein ICR mice. Each line gram represents the mean value ±SE. Analyzed by Fisher-test. *p<0.05,**p<0.01 vs control （↑ 2Gy whole body irradiation ） * * * * * * ｌ ymphocyte Gu Lab

13. Effect on anti-tumor by the sample medication. Each line represents the mean value ±S.E Analyzed by Dunnett-test. * * * * * * * * * * * * * * * * * * * * * * * * * * Tumor volume (non-irradiation group) * * * * * * * * * * * * * * * * *

14. Weight of tumor. Each line represents the mean value ±S.E. Analyzed by Dunett-test (n=7) Gu Lab Tumor weight (non-irradiation group)

15. Weight of tumor. Each line represents the mean value ±S.E. It was analyzed by Dunett-test (n=7) Gu Lab Tumor weight (irradiation group)

16. The free radical removal by SOD O2 O2 - An injury factor C H O DAN polymerase SH A replication of DNA error Chromosomal anomalies Approval of autoimmune disease An auto-immunity antigen A - antibody complex Bacteria A virus XOD blood cells, a macrophageWhite Stimulation We remove to SOD Deactivation

17. Reinforcement of removal + biophylaxis ability of a cause tumor inhibition mechanism Free radical elimination / antioxidation action The conduction that detoxication / Radhi Cal elimination is enzymatic Anti-inflammatory action DNA disorder (mutation) DNA restoration A mutation cell Cytostasis / apotosis conduction A cancer cell

18. Structure of tumor immunity by antigen-antibody reaction Natural killer cell Antigen fault acquired immunity Activation Natural killer cell A cancer cell An antibody An antibody-producing cell A killer cell T-helper cells B cell Antigen presentation A macrophage Antigen presenting cells Antigen acquired immunity A carcinoma antigen