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A very short presentation about the potential of games in the context of gene annotation

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  1. 1. CROWDSOURCING BIOCURATION WITH BIOLOGICAL GAMES Benjamin Good The Scripps Research Institute @bgood
  2. 2. BIOCURATORS FACED WITH MASSIVE ANDGROWING AMOUNT OF WORK• approaching 1 million articles 1,000,000 added to PubMed every year• By the end of my talk several 800,000 new papers will be have been added.... 600,000 new pubmed 400,000 articles 200,000 0 1979 1984 1989 1994 1999 2004 2009 year
  3. 3. HUMAN EFFORT AT MASSIVE SCALESeven million hours of human labor Empire State Building
  4. 4. HUMAN EFFORT AT MORE MASSIVE SCALE It is estimated that 9 billion hours of human labor were spent playing solitaire in 2005.Von Ahn L. : Google Tech Talk: Human Computation 2006.
  5. 5. HUMAN EFFORT AT TRULY MASSIVE SCALE Estimated that 150 billion hours spent playing games in 2010 1.6E+11 1.4E+11 1.2E+11 1E+11 8E+10 6E+10 hours worked 4E+10 2E+10 0 empire state one year of one year of building solitaire gamesMcGonigal J. Reality is broken : why games make usbetter and how they can change the world.New York: Penguin Press; 2011.
  6. 6. 50- 150 billion human hours per year
  7. 7. Seven million hours of human labor = 1 Empire State BuildingVon Ahn L. : Google Tech Talk: Human Computation 2006.
  8. 8. 150 billion hours of human game play = nothing
  9. 9. 150 billion hours of human game play = nothing
  10. 10. GAMES WITH A PURPOSELabel all images on the Web Devise protein folding algorithms Fix multiple sequence alignments Design RNA molecules
  11. 11. Annotate the human genome