The Models of Alzheimer's Disease Part I

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Speaker: Jimmy Lu
Topics: The Models of Alzheimer's Disease Part I
Date: 2011.02.19

WECO Lab, CSIE, FJU

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The Models of Alzheimer's Disease Part I

  1. 1. The Models of Alzheimer’s Disease (Part I)<br />Speaker : Jimmy Lu<br />Advisor : Hsing Mei<br />Web Computing Laboratory (WECO Lab)<br />Computer Science and Information Engineering Department<br />Fu Jen Catholic University<br />
  2. 2. Three models<br />Network damage model<br />General mechanism that destructs brain network<br />Pattern of lesions in Alzheimer’s disease<br />Accurate definition of the stage in AD<br />Cholinergic hypothesis<br />Parameters which affect the progress of the AD<br />Combine these three to an algorithm.<br />
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  4. 4. Amyloid<br />
  5. 5. Neurofibrillary Changes<br />
  6. 6. Hippocampus<br />
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  12. 12. Reference<br />H. Braak and E. Braak, Pattern of cortical lesions in Alzheimer's disease. In: K. Iqbal, B. Winblad, T. Nishimura, M. Takeda and H. M. Wisniewski, Editors, Alzheimer's Disease: Biology, Diagnosis, and Therapeutics, Wiley, New York (1997), pp. 227–237.<br />H. Braak and E. Braak, Neuropathologicalstageing of Alzheimer-related changes. ActaNeuropathol. 82 (1991), pp. 239–259.<br />

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