Cytopathic Effects Of Viral Infections

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Cytopathic Effects Of Viral Infections

  1. 1. Cytopathic effects of Viral Infections Genevi ève Learmonth
  2. 2. Viruses <ul><li>HPV </li></ul><ul><li>BK Virus </li></ul><ul><li>Respiratory Syncytial Virus </li></ul><ul><li>Cytomegalovirus </li></ul><ul><li>Herpes </li></ul>
  3. 3. BK Virus
  4. 4. BK Virus Histology of Renal Biopsy
  5. 5. BK virus: Histology Renal Biopsy , tubular cells
  6. 6. BK Virus: Multinucleated cell in tubule lining cells
  7. 7. BK virus tubular cell
  8. 8. Screening for Cytopathic effect of BK virus in urine specimens
  9. 9. Subtle Cytopathic changes
  10. 12. Immunostaining for BK virus
  11. 13. Immunostaining of Renal Biopsy BK Virus infection
  12. 14. Screening Urine for casts, organisms, crystals, inflammatory exudate
  13. 15. Cytological examination of Urine <ul><li>Background </li></ul><ul><li>Inflammatory exudate </li></ul><ul><li>Erythrocytes </li></ul><ul><li>Casts </li></ul><ul><li>Crystals </li></ul><ul><li>Pigment </li></ul><ul><li>Organisms: Viral cytopathic effect </li></ul><ul><li>Bacteria </li></ul><ul><li>Fungi </li></ul><ul><li>Parasitic Ova </li></ul>
  14. 18. Clinical problems <ul><li>Kidney Transplant </li></ul><ul><li>Bone Marrow Transplant </li></ul><ul><li>HIV/AIDS </li></ul><ul><li>Liver: Cholestasis </li></ul><ul><li>Lymphoma </li></ul><ul><li>Melanoma </li></ul>

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