Triglycerides

3,225 views

Published on

A lecture I almost had to give as a 'stand-in' for one of my colleagues. Probably the fastest I've ever prepared a lecture and the first time I have taken someone else's notes and effectively given them a 'presentation make-over. Never did give it but it seems pointless having it sitting around on my hard drive.

Published in: Education, Business, Technology
0 Comments
5 Likes
Statistics
Notes
  • Be the first to comment

No Downloads
Views
Total views
3,225
On SlideShare
0
From Embeds
0
Number of Embeds
781
Actions
Shares
0
Downloads
170
Comments
0
Likes
5
Embeds 0
No embeds

No notes for slide

Triglycerides

  1. 1. triglycerides ur p art 5 nit fo g.j.rowlands u ©anna_t@flickr
  2. 2. fats can ©*Micky@flickr taste...
  3. 3. ©Mrs Magic@flickr good!
  4. 4. provide more energy than carbohydrate or protein ©swisscan@flickr
  5. 5. but...
  6. 6. is not very good for s u ©Pixar / Disney
  7. 7. O O O O O O triglycerides
  8. 8. OH OH OH glycerol triglyceride formation
  9. 9. OH O OH 3x HO R OH glycerol fatty acid triglyceride formation
  10. 10. OH O OH 3x HO R OH glycerol fatty acid O O R O O R O R triglyceride O triglyceride formation
  11. 11. natural fats and oils ©Shereen M (away)@flickr
  12. 12. fatty acids O HO myristic acid ©JustABigGeek@flickr
  13. 13. fatty acids O HO oleic acid
  14. 14. fatty acids O HO ©Chris & Lara Pawluk@flickr linolenic acid
  15. 15. saturated fat O HO ©Thomas Hawk@flickr
  16. 16. unsaturated fat O HO ©darwin bell@flickr
  17. 17. O HO polyunsaturated fat ©Marco Veringa@flickr
  18. 18. always cis-alkenes O HO
  19. 19. trans-fatty are processed acids O HO ©cultr.sun@flickr
  20. 20. saturated chains CO2H
  21. 21. saturated chains CO2H pack well
  22. 22. high melting points ©niznoz@flickr solids
  23. 23. kinked unsaturated chains CO2H
  24. 24. kinked unsaturated chains CO2H don’t
  25. 25. low melting points ©☻mrhappy☻@flickr oils
  26. 26. reactions ©euthman@flickr
  27. 27. O HO addition Br Br reactions O Br Br HO
  28. 28. O HO H H metal catalyst hydrogenation O H H HO
  29. 29. O unsaturated HO H H metal catalyst hydrogenation O H H HO saturated
  30. 30. of synthesis margarine ©NontrivialMatt@flickr
  31. 31. ester hydrolysis O NaOH O R2 HO R2 R1 O R1 O Na saponification
  32. 32. ester hydrolysis O O O O O O NaOH H2O OH 3x O OH Na O OH
  33. 33. soap O Na O
  34. 34. how does soap work?
  35. 35. O Na O polar non-polar hydrophilic hydrophobic
  36. 36. micelle hydrophobic pocket
  37. 37. micelle hydrophilic carboxylate interacts with water ion-dipole interactions
  38. 38. grease / dirt hydrophobic
  39. 39. non-polar micelle hydrophobic portion inside away from water
  40. 40. detergents polar non-polar hydrophilic hydrophobic head tail
  41. 41. synthesis of a detergent H2SO4 electrophilic aromatic substitution HO3S NaOH Na O3S
  42. 42. stronger acid more ©fdecomite@flickr robust
  43. 43. anionic detergent O S O O
  44. 44. cationic detergent N Cl
  45. 45. cationic detergent N Cl germicidal ©AJC1@flickr
  46. 46. fatty acid metabolism
  47. 47. 1 hydrolysis O O O O O O your belly OH 3x O OH O OH
  48. 48. 2 metabolism O O CoA-SH esterification (coenzyme A) O CoA S dehydrogenation H H O CoA S
  49. 49. 2 metabolism O CoA S hydration H2O O OH CoA S H oxidation H H O O CoA S
  50. 50. 2 metabolism O O CoA S CoA-SH C–C (coenzyme A) splitting O CoA S O CoA S
  51. 51. and repeat ©estherase@flickr
  52. 52. energy from breaking bonds C H ©laverrue@flickr
  53. 53. O HO more C–H than O HO
  54. 54. fat stores 2x energy of ©Great Beyond@flickr sugar
  55. 55. thanks to Trevor Kitson

×