Prostate disease

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Prostate disease

  1. 1. Prostate Disease Important information for men !
  2. 2. Test your prostate knowledge
  3. 5. 3 most common disease of the prostate <ul><li>Benign Prostatic Hyperplasia </li></ul><ul><li>Prostate Cancer </li></ul><ul><li>Prostatitis (inflammation of the prostate) </li></ul><ul><li>Important ! </li></ul><ul><li>Men > 35years old should be aware of these problems. </li></ul>
  4. 6. What is the prostate? <ul><li>Small gland, size & shape of chestnut </li></ul><ul><li>20g, 1.2 inches </li></ul><ul><li>Situated below the bladder, surrounding the urethra. Urethra is the passage that carries the urine from the bladder through the penis during urination. </li></ul><ul><li>Important! </li></ul><ul><li>Women do not have prostate. </li></ul>
  5. 8. What is the function of the prostate? <ul><li>Secretes fluid that forms part of the semen. </li></ul><ul><li>Prostate fluid provides nourishment and energy for the sperm to be active and be able to ‘swim’. </li></ul>
  6. 9. How do I know if I have a prostate problem? <ul><li>The following symptoms suggest a prostate problem:- </li></ul><ul><li>Frequent urination </li></ul><ul><li>Waking up at night to urinate </li></ul><ul><li>Unable to postpone urination </li></ul><ul><li>Feeling being unable to empty the bladder </li></ul><ul><li>Delay in starting to urinate </li></ul><ul><li>Weak urination stream – straining </li></ul><ul><li>Intermittent stream – stopping & starting </li></ul><ul><li>Incontinence – loss of urinary control </li></ul>
  7. 10. Other symptoms:- <ul><li>Painful urination </li></ul><ul><li>Blood in urine </li></ul><ul><li>BPH and prostate cancer can cause similar symptoms but early prostate cancer does NOT produce any symptoms. </li></ul>
  8. 11. What is Benign Prostatic Hyperplasia? <ul><li>With increasing age, the prostate tissue will grow and thicken. </li></ul><ul><li>Normal weight 20g 150g </li></ul><ul><li>BPH is present in 80% of 60 year old men. </li></ul><ul><li>Changes due to change in hormone as men age and environmental factors </li></ul><ul><li>Eg) Diet. </li></ul>
  9. 13. How is BPH diagnosed? <ul><li>Digital examination </li></ul>
  10. 14. <ul><li>If there are any lumps, the doctor will suggest other tests </li></ul><ul><li>eg) urinalysis, biopsy, blood test, </li></ul><ul><li>Treatment?? </li></ul><ul><li>Prostatectomy – remove inner obstruction ( TURP ) </li></ul><ul><li>Drugs to shrink or relax prostate. </li></ul><ul><li>Microwaves treatments, prostate stents, lasers </li></ul>
  11. 15. Prostate cancer <ul><li>Most common cancer in elderly men and the 2 nd most common cause of cancer-related death in men. </li></ul>
  12. 16. What is cancer? <ul><li>Cells in the body normally grow in an organized, controlled manner with new cells replacing dying cells. </li></ul><ul><li>When this control is lost, cells can grow rapidly and abnormally, forming a tumor or growth. </li></ul><ul><li>Some of these are called benign because they grow slowly and do not spread elsewhere in the body. </li></ul>
  13. 17. <ul><li>Other tumors invade and destroy normal tissue and spread (metastasize) to other parts of the body where they can grow. </li></ul><ul><li>These tumors are malignant and are called cancerous cells. When they spread to other parts of the body, they are called metastases. </li></ul>
  14. 18. What is prostate cancer? <ul><li>Cancer of the prostate. </li></ul><ul><li>Early stages causes no symptoms </li></ul><ul><li>This cancer can spread to lymph nodes and blood circulation causing cancer in other parts of the body. Eg) bones </li></ul><ul><li>BPH & cancer can occur together in the prostate. </li></ul>
  15. 23. How is prostate cancer detected? <ul><li>DRE reveals a lump. </li></ul><ul><li>Blood test is abnormal, prostate specific antigen (PSA). </li></ul><ul><li>Not all lump is a cancer. PSA is produced by prostate. Level suspicious. </li></ul><ul><li>Prostate biopsy. </li></ul><ul><li>Transrectal ultrasound ( TRUS ) </li></ul>
  16. 24. Treatment <ul><li>Surgical removal </li></ul><ul><li>Radiation therapy </li></ul><ul><li>Hormonal therapy </li></ul>Early detection and prevention is still the best !
  17. 25. Prostatitis <ul><li>3 types of prostatitis:- </li></ul><ul><li>Acute bacterial prostatitis </li></ul><ul><li>Chronic bacterial prostatitis </li></ul><ul><li>Non-bacterial prostatitis </li></ul>
  18. 26. How is prostatitis diagnosed? <ul><li>DRE </li></ul><ul><li>Urine specimens </li></ul><ul><li>Treatment? </li></ul><ul><li>Antibiotics </li></ul><ul><li>Muscle relaxants </li></ul><ul><li>Anti-inflammatory </li></ul>
  19. 27. Supplements shown to help prevent and reduce prostate problems. <ul><li>Widely used in other countries to treat BPH. 50% treatment in Italy and 90% treatments in Germany. </li></ul><ul><li>Reduce symptoms of BPH. </li></ul><ul><li>Similar efficacy to medications such as finasteride ( Proscar ). Better tolerated & less expansive. </li></ul><ul><li>American Family Physician 2003; 67:1281-3, 2003) </li></ul>Saw Palmetto
  20. 28. Broccoli Contains chemicals that block growth of human prostate cancer cells and aid in cancer prevention. Major compound, indole-3-carbinol ( 13C ) have cancer prevention properties. 13C converted to DIM, which acts as powerful male hormone blocker and stops prostate cancer cells from growing and dividing. Dihydrotestosterone ( DHT ) is the primary male hormone that causes prostate cancer. Journal of Biological Chemistry, University of California, June 6, 2003
  21. 29. Pygeum <ul><li>First used by Zulu tribe in Africa. </li></ul><ul><li>Most popular treatment for symptoms of BPH in France, Italy and America. </li></ul><ul><li>Worldwide demand increased, in 1998 it was a threatened species. </li></ul><ul><li>Inhibits binding of DHT to receptors. </li></ul><ul><li>Reduce symptoms of mild to moderate BPH. </li></ul><ul><li>Good tolerability. </li></ul>
  22. 30. Soya and Isoflavones <ul><li>In 1990, the US National Cancer Institute allocated USD 3 million to study anti-cancer properties of soy. </li></ul><ul><li>Soya bean isoflavones, genistin inhibits growth of all types of cancer cells. </li></ul><ul><li>It also reduce and inhibit prostate tumor development and growth. </li></ul><ul><li>1 serving of soya per day was associated with 70% reduction in prostate cancer. </li></ul><ul><li>Isoflavones also responsible in preventing progression of latent prostate cancer to the more advance form of cancer. </li></ul>
  23. 31. Zinc and Selenium <ul><li>Important for normal cellular function. </li></ul><ul><li>Dosage is important. Recommended:- </li></ul><ul><li>Zinc = 11mg – 40 mg/day </li></ul><ul><li>Selenium = 55 – 400 mg/day </li></ul><ul><li>American Institute of Medicine of the National Academies, Dietary reference intakes. </li></ul>
  24. 32. Calcium d-Glucarate <ul><li>A form of glucaric acid. Enhances process of glucuronidation, a process by which the body rids itself of dangerous carcinogens and harmful chemicals. </li></ul><ul><li>Non-toxic, natural substance in fruits and vegetables. </li></ul><ul><li>Highly protective against cancer – lung, skin, liver, breast, colon and prostate. Reduce cancer by 60% ( Walaszek, 1990 ) </li></ul><ul><li>Enhance the detoxification of carcinogens and androgens and inhibits prostate cancer. </li></ul><ul><li>M.D Anderson Cancer Centre, No.2 cancer center in USA. </li></ul>
  25. 33. Lycopene <ul><li>Anti-cancer properties </li></ul>
  26. 34. Zinc & Selenium Saw Palmetto Isoflavones Lycopene Pygeum Extract Nettle Extract Soya Bean Extract Broccoli Extract Calcium d-Glucarate
  27. 35. 4Life Targeted Transfer Factor <ul><li>Helps keep the immune system efficient. </li></ul><ul><li>From cow colostrum and chicken egg yolk. </li></ul><ul><li>Small protein 10,000 Daltons. </li></ul><ul><li>Simple protein, easily absorbed. Goes directly into blood stream and lymphatics to immune cells. </li></ul><ul><li>Educate immune cells to recognize, respond and remember invaders. </li></ul>

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