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Holistic Approach MS version 6.0

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Holistic Approach MS version 6.0

  1. 1. Epstein Bar Virus Genetics Vitamin D Smoking Risk:Benefit ratio Adverse events Differential Diagnosis At risk Moderate impairment Severe impairment Terminal Phase MRI Evoked Potentials Lumbar puncture Blood Tests Diagnostic Criteria Cognition Depression Fatigue Bladder Bowel Sexual dysfunction Tremor Pain Swallowing SpasticityFalls Balance problems Insomnia Restless legsFertility Clinical trials Gait Pressure sores Oscillopsia Emotional lability Seizures Gastrostomy Rehab Suprapubic catheter Intrathecal baclofen Physio- therapy Speech therapy Occupational Therapy Functional neurosurgery Colostomy Tendonotomy Studying Employment Relationships Travel Vaccination Anxiety Driving Nurse specialists Family counselling Relapse-free 2nd line Maintenance EscalationInduction Monitoring Disease-free Progression-free DMTs Side effects Advanced Directive Exercise Diet Alternative Medicine Pregnancy Breast Feeding Research Insurance Visual loss Palliative Care Assisted suicide Social services Legal aid Genetic counselling An holistic approach to MS; beta ver. 6.0 Intrathecal phenol Fractures Movement disorders Osteopaenia Brain reserve Hearing loss Tinnitus Photophobia Hiccoughs DVLA Neuroprotection Psychosis DepersonaliationBrain Health Cognitive Reserve Sudden death Suicide OCD Narcolepsy Apnoea Carers Respite Hospice Respite Dignitas Advanced Directive Rhiztomy Wheelchair Walking aids Blood/Organ donation Brain donation CBT NABs Autoimmunity Infections Outcome measures Web Resources Pathogenesis Double vision What is MS? NEDA T2T OCT Neurofilaments PML Risk Pharma Anaesthesia RIS CIS Minimal impairment 1st line 3rd line Sub-clinical activity End-organ damage Pharmacovigilance Tolerability Adherence Cost-effectiveness EDSS MSFC PASAT PROMS 9H-PT 25F-TW MRI Brain atrophy Anti-inflammatory Remyelination Neuro-restoration Premature ageing Number needed to treat Interferon-beta Glatiramer acetate Teriflunomide Dimethyl fumarate Fingolimod Natalizumab Alemtuzumab Azathioprine Methotrexate Mitoxantrone Cyclophosphamide Teratogenic Pregnancy Breast feeding Hepatotoxicity Bone marrow suppression Lymphopaenia Neutropenia Secondary autoimmunity Daclizumab Rituximab Ocrelizumab Ofatumumab Laquinimod Cladribine BMT Infusion reactions Injection site reactions Anaphylaxis Cardiotoxicity Nephrotoxicity Pharmacodymanics Pharmacokinetics Decision-aid ICP NICE NHS England ABN Guidelines Steroids IVIG Lipoatrophy Exercise therapy Acupuncture TENS FES Low contrast visual acuity Number needed to harm PML Opportunistic infectionsContraception Hair loss Dermatoxicity Licensed DMTs Unlicensed DMTs DMTs in late-stage development Spinal cord stimulator Peripheral nerve stimulation Mindfulness therapy Complementary Medicine Brain training Cognitive Rehabilitation CPAP Plastic surgery Neuralgia Hyperacusis Living Will Dignified dying Funeral Planning Mortality Anti-depressants Tricyclics Anxiolyitics Amantadine Modafanil Anti-cholinergics Urinary antiseptics Antibiotics Baclofen Tizanidine Clonazepam Diazepam Dantrolene Botox Gabapentin Pregabalin Amitriptyline Duloxetine Anti-convulsants Phenytoin Carbamazepine Oxcarbazepine Lamotrigine Levitiracetam Sativex Laxatives Bulking agents Prokinetic agents Osmotic agents Vitamin D Calcium supplements BisphosphonatesAnti-emetics Anti-vertigo Anti-psychotics Parkinsonism Obesity Smoking Hypertension Diabetes Bone health Exercise Depression Anxiety Alcoholism Diet Prevention Diagnosis DMT Symptomatic Therapist Terminal Counselling Comorbidities Symptomatic Meds BARTS-MS Copyright Professor Giovannoni 27 June 2016 Long-term Remission MS Cure Normal Ageing Diet & Supplements Exercise Alcohol Sleep Smoking Stress Lifestyle Wellness Intellectual Emotional Social Spiritual Physical Occupational Envirobmental Multiple Sclerosis Under construction

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