Francisco Muñoz Maestre
A NEW PATHOGENIC E COLI
Index
 Introduction
 Pathogenics E. coli
 New pathogenic E. coli
 Case study
 Symptoms and cures
 Bibliography
INTRODUCTION
 What is E. coli ?
E. coli is a bacteria, inhabitant of our gastrointestinal tract and
one of bacterial spec...
PATHOGENICS E. COLI 1
 There are a lot of types but I’m going to explain most important
types:
 ENTEROTOXIGENIC ESCHERIC...
PATHOGENICS E. COLI 2
 ENTEROHEMORRHAGIC ESCHERICHIA COLI (EHEC)capable
of producing Shiga toxin
 ENTEROINVASIVE ESCHERI...
NEW PATHOGENIC E COLI
O104:H4
 First isolates date back to 2001, described like HUSEC41
 It turned up again in 2006, in ...
NEW PATHOGENIC CASE
 Between 2 May and 14 June 2011, 3,332 cases (818
cases of HUS) from 13 European Union Member
States,...
 There are two symptoms that are special in this E. coli:
bloody diarrhea and Hemolytic-uremic syndrome (HUS, the
major s...
BIBLIOGRAPHY
• http://www.sciencedirect.com/science/article/pii/S14733099
11701657
• http://www.i-sis.org.uk/
E_coli_O104_...
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A new pathogenic e coli francisco muñoz maestre

  1. 1. Francisco Muñoz Maestre A NEW PATHOGENIC E COLI
  2. 2. Index  Introduction  Pathogenics E. coli  New pathogenic E. coli  Case study  Symptoms and cures  Bibliography
  3. 3. INTRODUCTION  What is E. coli ? E. coli is a bacteria, inhabitant of our gastrointestinal tract and one of bacterial species most frequently isolated in cultures.  When is E. coli a pathogenic bacteria? When they acquire certain genetic material.
  4. 4. PATHOGENICS E. COLI 1  There are a lot of types but I’m going to explain most important types:  ENTEROTOXIGENIC ESCHERICHIA COLI (ETEC) watery diarrhea in young humans and other mammals  ENTEROPATHOGENIC ESCHERICHIA COLI (EPEC)most commonly among children less than six months of age in developing countries
  5. 5. PATHOGENICS E. COLI 2  ENTEROHEMORRHAGIC ESCHERICHIA COLI (EHEC)capable of producing Shiga toxin  ENTEROINVASIVE ESCHERICHIA COLI (EIEC)closely related to Shigella and causes disease that is similar to shigellosis  ENTEROAGGREGATIVE ESCHERICHIA COLI (EAEC) acute diarrheal illness among many different subpopulations in both developing and industrialized regions
  6. 6. NEW PATHOGENIC E COLI O104:H4  First isolates date back to 2001, described like HUSEC41  It turned up again in 2006, in a woman who contracted HUS in Korea.  The current is a recombinant of two pathogenic E. coli types, enterohaemolytic E. coli (EHEC) and enteroaggregative E. coli (EAEC)  E. coli O104:H4 also contains an array of antibiotic resistance genes conferring resistance to a lot of antibiotic like ampicillin, amoxicillin, streptomycin, …
  7. 7. NEW PATHOGENIC CASE  Between 2 May and 14 June 2011, 3,332 cases (818 cases of HUS) from 13 European Union Member States, and 36 patients died.  95% from Germany and they came from northern Germany  Some 100 patients need an organ transplant or will require dialysis.  The source was vegetable sprouts from an organic farm in Lower Saxony in northern Germany.
  8. 8.  There are two symptoms that are special in this E. coli: bloody diarrhea and Hemolytic-uremic syndrome (HUS, the major systemic complication of EHEC infection)  There are a lot of experiments but there aren’t any cure now for that.
  9. 9. BIBLIOGRAPHY • http://www.sciencedirect.com/science/article/pii/S14733099 11701657 • http://www.i-sis.org.uk/ E_coli_O104_H4_Newly_Emergent_Pathogen.php • http://www.uptodate.com/contents/pathogenic-escherichia- coli • http://www.uptodate.com/contents/clinical-manifestations- diagnosis-and-treatment-of-enterohemorrhagic-escherichia- coli-ehec?source=see_link

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