Francisco Muñoz Maestre
A NEW PATHOGENIC E COLI
Pathogenics E. coli
New pathogenic E. coli
Symptoms and cures
What is E. coli ?
E. coli is a bacteria, inhabitant of our gastrointestinal tract and
one of bacterial species most frequently isolated in cultures.
When is E. coli a pathogenic bacteria?
When they acquire certain genetic material.
PATHOGENICS E. COLI 1
There are a lot of types but I’m going to explain most important
ENTEROTOXIGENIC ESCHERICHIA COLI (ETEC) watery
diarrhea in young humans and other mammals
ENTEROPATHOGENIC ESCHERICHIA COLI (EPEC)most
commonly among children less than six months of age in
PATHOGENICS E. COLI 2
ENTEROHEMORRHAGIC ESCHERICHIA COLI (EHEC)capable
of producing Shiga toxin
ENTEROINVASIVE ESCHERICHIA COLI (EIEC)closely related
to Shigella and causes disease that is similar to shigellosis
ENTEROAGGREGATIVE ESCHERICHIA COLI (EAEC) acute
diarrheal illness among many different subpopulations in both
developing and industrialized regions
NEW PATHOGENIC E COLI
First isolates date back to 2001, described like HUSEC41
It turned up again in 2006, in a woman who contracted HUS
The current is a recombinant of two pathogenic E. coli
types, enterohaemolytic E. coli (EHEC) and
enteroaggregative E. coli (EAEC)
E. coli O104:H4 also contains an array of antibiotic resistance
genes conferring resistance to a lot of antibiotic like
ampicillin, amoxicillin, streptomycin, …
NEW PATHOGENIC CASE
Between 2 May and 14 June 2011, 3,332 cases (818
cases of HUS) from 13 European Union Member
States, and 36 patients died.
95% from Germany and they came from northern
Some 100 patients need an organ transplant or will
The source was vegetable sprouts from an organic farm
in Lower Saxony in northern Germany.
There are two symptoms that are special in this E. coli:
bloody diarrhea and Hemolytic-uremic syndrome (HUS, the
major systemic complication of EHEC infection)
There are a lot of experiments but there aren’t any cure now