Ulcerative colitis is a chronic, or
long-lasting, disease that causes inflammation and sores, called ulcers, in the
inner lining of the large intestine, which includes the colon and the
rectum—the end part of the colon.
UC is one of the two main forms of chronic
inflammatory disease of the gastrointestinal tract, called inflammatory bowel
disease (IBD). The other form is called Crohn’s disease.
Normally, the large intestine absorbs water
from stool and changes it from a liquid to a solid. In UC, the inflammation
causes loss of the lining of the colon, leading to bleeding, production of pus,
diarrhea, and abdominal discomfort.