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CYSTICERCOSIS
OPTOM FASLU MUHAMMED
 Cysticercosis refers to tissue infection after
exposure to eggs of Taenia solium, the pork tape
worm.
 The disease is s...
 Cysticercosis should be differentiated from
taeniasis carriage of the adult tape worm in the
intestine (which is through...
 Agent: Taenia solium (pork tape worm)
 The common larval stage of Taenia solium was
also known as cysticercus cellulosa
TRANSMISSON
 Humans are Taenia solium reservoirs.
 Eating under cooked pork that contain viable
cysticerci.
 Large no. ...
LIFE CYCLE
1
2
3
4 5
6
 Two host life cycle
 Human beings are the only definitive host
 Both humans and pigs can act as intermediate host
BASICS OF INFECTION CYCLE
 Tapeworm larval cyst (cysticercus) is ingested with
poorly infected meat.
 Larva escapes the ...
 Humans also can be the intermediate host causing
cysticercosis if they ingest eggs.
 Two different forms in human:-
 H...
Human taeniasis
 The scolex attaches to the mucosa and begins
forming segments (proglottis)
 After two months of infecti...
HUMAN CYSTICERCOSIS
 Internal auto infection is also possible
 The invasive oncoshere (embryos) the eggs are
liberated b...
 Muscles: small, palpable, movable nodules
 Chest and arms: mild or no symptoms
 Ophthalmic cysticercosis: intraocular ...
CYSTICERCOSIS IN MUSCLE
 Cysticerci can develop in any voluntary muscle in
humans
 Invasion of muscle by cysticerci can ...
Cysticercosis
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Cysticercosis

  1. 1. CYSTICERCOSIS OPTOM FASLU MUHAMMED
  2. 2.  Cysticercosis refers to tissue infection after exposure to eggs of Taenia solium, the pork tape worm.  The disease is spread via the oral route through contaminated food and water, and is primarily a food born disease.  After ingestion the eggs pass through the lumen of the intestine into the tissue and migrate preferentially to the brain and muscles.
  3. 3.  Cysticercosis should be differentiated from taeniasis carriage of the adult tape worm in the intestine (which is through ingestion of cysts in an intermediate host, not the ingestion of the eggs as in cysticercosis)  These represents two different stages of the parasite’s life cycle.
  4. 4.  Agent: Taenia solium (pork tape worm)  The common larval stage of Taenia solium was also known as cysticercus cellulosa
  5. 5. TRANSMISSON  Humans are Taenia solium reservoirs.  Eating under cooked pork that contain viable cysticerci.  Large no. of eggs which pass out in the feces  The presence of an adult tape worm in the gut is reasonably harmless.  This condition is known as cysticercosis.
  6. 6. LIFE CYCLE 1 2 3 4 5 6
  7. 7.  Two host life cycle  Human beings are the only definitive host  Both humans and pigs can act as intermediate host
  8. 8. BASICS OF INFECTION CYCLE  Tapeworm larval cyst (cysticercus) is ingested with poorly infected meat.  Larva escapes the cyst and attaches to the mucosa by the scolex.  Feces are contaminated with eggs (persists for several days in the environment) consumed by pigs (eggs are hatched and form cysticerci)
  9. 9.  Humans also can be the intermediate host causing cysticercosis if they ingest eggs.  Two different forms in human:-  Human taeniasis  Human cysticercosis
  10. 10. Human taeniasis  The scolex attaches to the mucosa and begins forming segments (proglottis)  After two months of infection, gravid proglotids begin to detach from the distal end- excreted in the feces.  Each segment contains 60,000 eggs  Worm causes only minor inflammation to the intestine(mild symptoms- abdominal pain, diarrhoea and naussea)
  11. 11. HUMAN CYSTICERCOSIS  Internal auto infection is also possible  The invasive oncoshere (embryos) the eggs are liberated by the action of gastric acid and cross the bowel wall  They estalished at small terminal vessels (muscles, brain, eye) where they grow about the size of 1cm in 2-3 months.
  12. 12.  Muscles: small, palpable, movable nodules  Chest and arms: mild or no symptoms  Ophthalmic cysticercosis: intraocular cysts floating freely in the vitreous humor, decreased visual acuity  Neurocysticercosis: most symptoms are because of the inflammatory reactions associated with cyst degeneration (that may take years to happen)- epilepsy, hydrocephalus, encephalitis, meningitis
  13. 13. CYSTICERCOSIS IN MUSCLE  Cysticerci can develop in any voluntary muscle in humans  Invasion of muscle by cysticerci can cause myositis, with fever, eosinophilia and muscular pseudo hypertrophy
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Cysticercosis by faslu muhammed

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