Jacques Benveniste
A TRUE LEGEND AMONG MYTHS
The preservation of an outstanding French scientist and his research

Outstanding French scientist Jacques Benveniste (1935-2004) - author of over 300
scientific articles on medicine related to the area of molecular biology, was known as a
successful researcher who discovered a new, important lipid mediator. According to
colleagues, Benveniste was a potential Nobel Prize candidate for his research
discoveries.
Approaching the peak of success, Jacques Benveniste unexpectedly departed from the
conventional scientific arena in order to concentrate on less traditional forms of
research. In 1998, the authoritative London weekly scientific journal Nature published
his article with co-authors Davenas, E., Beauvais, F., Amara, J., Oberbaum, M.,
Robvizon, B., Miadonna, A., Tedeschi, A., Pomeranz, B., Fortner, P., Belon, P., Sainte-
Laudy, J., Poitevin, B. & Benveniste, J., Titled: Human basophil degranulation triggered
by very dilute antiserum against IgE. Nature, 333, 816-818. The published article had
presented astounding results from Benveniste unconventional research. The
controversial article caused heated debates amongst the prevailing scientific dogma in
physics, chemistry and biology.
The inability to consistently repeat his experiments resulted in Jacques Benveniste being
rejected by the scientific community, deprived of laboratory accesses and dismissed
from the INSERM in Paris. These harsh actions from the scientific community would
eventually lead investigative researchers to consider if the Benviniste experiments had
actually damaged the reputation of the institution.

J. Benveniste’s research created a divide in the scientific community. Some scientists
continued forward with these experiments in the study of this phenomena discovered by
J. Benveniste. Based on scientific research findings they had also come to declare that
J. Benveniste work was ethical and warranted further investigative research. Contrary to
current knowledge and concepts, opposing scientific researchers would not accept the
results.
In 2014, 26 years has passed since the J. Benveniste publication in the Nature journal,
from which came the discovery phenomena journalists now call "Memory of Water”. The
time has come, to find out who is right.

Confirmation of the Benveniste Results with High Dilutions
by independent research
• Belon P, Cumps J, Ennis M, Mannaioni PF, Sainte-Laudy J,
Roberfroid M, et al. Inhibition of human basophil degranulation by
successive histamine dilutions: results of a European multi-centre
trial. Inflamm Res 1999; 48: S17–8.
• Brown V, Ennis M. Flow-cytometric analysis of basophil activation:
inhibition by histamine at conventional and homeopathic
concentrations. Inflamm Res 2001; 50(Suppl 2):S47–S48
• Lorenz I, Schneider EM, Stolz P, Brack A, Strube J. Sensitive flow
cytometric method to test basophil activation influenced by
homeopathic histamine dilutions. Forsch Komplementarmed Klass
Naturheilkd 2003; 10:316–24.
• Belon, P, Cumps, J, Ennis, M et al. Histamine dilutions modulate
basophil activation. Inflamm res 2004; 53:181-188.
+ several other studies of the same and other authors.

In spite of hardships, Jacques Benveniste continued his research in a personal
laboratory. He had acquired an even stronger character and an iron willpower that
provided him footing to forge new pathways into his scientific research. He began new
experiments - a transmission of signals from biologically active substances through
communication lines.
Following Benveniste’s death in 2004, this direction of his charactered research is
continued and expanded upon by successors alike, resulting in the further affirmations of
the controversial experiments.

Based on J. Benveniste observations; the effects of “Ultra-High Dilutions”
were abolished by magnetic fields. He suggested that the signaling of EM
waves are potentially transmittable to cells and water by electromagnetic
means.
In 1991 Benveniste implemented the Electronic
Transmission of “Informational Copies” (IC) of
biologically active substances (BAS) to water.

The Principle Scheme was that of a device for Electronic Transmission
of IC of BAS Output coil Input coil Solution of BAS Amplifier (oscillator)
Water (IC of BAS).
Output
coil
Input
coil
Solution of BAS
Amplifier
(oscillator)
Water
(informational copy of
BAS)

“…normal human neutrophils
reacted to PMA transmitted via an
electronic oscillator by reducing
cytochrome c as though they had
been directly exposed to PMA. This
phenomenon was not observed
when the oscillator was turned
off…, when protein kinase inhibitors
were added to neutrophils…, when
active PMA in the input solution
was substituted by its inactive
analogue The results of 10
independent blind experiments
Transmitted PMA Transmitted
vehicle”
The results of 10 independent blind experiments
Transmitted PMA
Transmitted vehicle

IC of acetylcholine, histamine, ovalbumin and other
BAS had been transmitted to distant addressees
using communication networks including Internet
J. Benveniste, P. Jurgens, W. Hsueh, J. Aissa TRANSATLANTIC TRANSFER OF DIGITIZED
ANTIGEN SIGNAL BY TELEPHONE LINK. J. Allergy Clin. Immunol., 99:S175 (1997).
Benveniste, J., Benveniste L., Guillonnet, D. 2010. Method and system for producing a substance
or a signal with a coagulating or anticoagulant effect. US Patent N◦ 0 233, 296 A1
J. Benveniste
Paris, France
W. Hsueh
Chicago, USA
Water treated with IC of BAS exerted specific effects on the biological test systems
Internet

• Montagnier L., et al. (2009) Electromagnetic signals are produced by aqueous
nanostructures derived from bacterial DNA sequences., Interdiscip. Sci. Comput. Life Sci.,
1: 245-253.
• Montagnier, L., Aissa, J., Del Giudice, E., Lavallée, C., Tedeschi, A. & Vitiello, G. 2011.
DNA waves and water. Journal of Physics: Conference Series. 306: 012007.
• Foletti A., et al. (2011) Differentiation of human LAN-5 neuroblastoma cells induced by
extremely low frequency electronically transmitted retinoic acid. JACM 17(8), 701-704.
• Foletti A., et al. (2012) Experimental finding on the electromagnetic information transfer of
specific molecular signals mediated through the aqueous system on two human cellular
models. JACM 18(3), 258-261
• Foletti A. et al, Electromagnetic Information Delivery as a New Perspsctive in Medicine,
PIERS Proceedings, Stockholm, Sweden, Aug. 12-15, 2013
• Citro M, Smith CW, Scott-Morley A, Pongratz W, Endler PC. Transfer of information from
molecules by means of electronic amplification. In: Endler PC, Schulte J, editors. Ultra high
dilution: physiology and physics. Dordrecht (Nederland): Kluwer Academic Pub.; 1994.
209-214.
• P. C. Endler, W. Pongratz, C. W. Smith, J. Schulte, F. Senekowitsch, M. Citro. Non-Molecular
Information Transfer from Thyroxine to Frogs. Signals and Images 1997, pp 149-159
• J.A. Heredia-Rojas, R. Gomez-Flores, A. O. Rodriguez-de la Fuente, E. Monreal-Cuevas, A.
C. Torres-Flores, L. E. Rodriguez-Flores, M. Beltcheva, A. C. Torres-Pantoja. Antimicrobial
effect of amphotericin B electronicallyactivated water against Candida albicans. African
journal of Microbiology Research 6(15). 2012, pp. 3685-3689
Confirmation of the Phenomena
Electromagnetic Information Transfer of Specific Molecular Signals

Existing scientific research in these subjects has lead us to the further inquiry
and support of an outstanding French scientist by the name of Jacques
Benveniste – a scientist, who challenged the dogma of modern thinking, and
should be given a fair historical assessment.
THUS, THE PRINCIPLE OF ELECTRONIC
TRANSMISSION OF BIOLOGICAL ACTIVITY OF
SPECIFIC SUBSTANCES ON AQUEOUS SYSTEMS IS
CONFIRMED BY QUITE A FEW OF INDEPENDENT
RESEARCHERS.

Brian Josephson, Nobel Laureate for Physics in 1973 invited Benveniste to the
Cavendish Laboratory in Cambridge.
Josephson was quoted: ‘We invited him to learn more about the research which
seems both scientifically interesting and potentially of considerable practical
importance. Jacques definitely recognized there was a problem with reproducing
the effect. The situation seemed to be that in some circumstances you had
reproduction and in others you didn’t; but the overall results were highly
significant.’
Brian Josephson had also made a point that many scientists have a "pathological
disbelief" in certain subjects that ultimately create an unhealthy and unscientific
attitude, thus creating blocks from real truth and real science. Skepticism is at its
best when its advocates do not undermine the conversation of the subject at hand;
but instead, explore all possible ways (conventional and non-conventional) to
understand and verify strange but compelling phenomena. We all have this
challenge as we explore and evaluate the biological and clinical effects of
homeopathic medicines.
Support from Brian Josephson
Yolene Thomas. The history of the Memory of Water. Homeopathy (2007) 96, 151–157
Article of Dana Ullman. Evidence Based HomeopathLinks:

A recent interview in the journal Science, Luc Montagnier (Nobel Laureate in
2008 for discovering the AIDS virus) expressed real concern about the
unscientific atmosphere that presently exists on certain unconventional
subjects.
"I am told that some people have reproduced Benveniste's results, but
they are afraid to publish it because of the intellectual terror from people
who don't understand it.“
Montagnier concluded the interview when asked if he is concerned that he is
drifting into pseudoscience, he replied adamantly: "No, because it's not
pseudoscience. It's not quackery. These are real phenomena which deserve
further study…For me Jacques Benveniste is a great researcher, as you
pointed out, and it's really scandalous the way he was treated. He died, as you
know, in 2004, we can say exhausted by all that struggling and I believe that
one day soon, he will be completely rehabilitated. I think it is a matter as
important as the Galileo affair.”
Support from Luc Montagnier
Article of Dana Ullman. Evidence Based Homeopath
France-Inter - Stéphane Paoli et Sandra Freeman, May 2, 2010Links:

In memoriam Jacques Benveniste, Chicago, Illinois, USA, March 2005
Support from Wei Hsueh
Link:
Prof. Wei Hsueh, M.D., Chicago, Illinois, USA:
“…It was disaster after disaster. Things turned upside down. Gradually, everything was
taken away from him: his budget, his staff, and finally his lab. Till today I can’t understand
how come the scientific community in France and in the world turned a completely
deaf ear to the success of his subsequent experiments that confirmed the earlier
results of the Nature paper? The study, as you all know, was performed in collaboration
with none other than Dr. Spira, a leading statistician in France, and the data were
supported by impeccable statistical analysis.
When I met Jacques again in a meeting a few years later, I thought he would have looked
defeated and dejected. I was certain that he would give up his unorthodox research, and
return to the main stream. It was quite the contrary. Jacques appeared highly spirited, and
told me that he had launched a new research project using electronically transmitted
signals to stimulate human neutrophils…
…This peculiar discovery may sound something of only casual interest for the curious, but
if you think about it carefully, you’ll realize that its potential impact is enormous…
…Most importantly, this discovery changed our entire traditional concept about
biology…”

• Davenas, E., Poitevin, B. & Benveniste, J. Effect on mouse peritoneal macrophages of orally administered very high
dilutions of silica. Eur. J. Pharmac. (1987), 135, 313-319.
• Davenas, E., Beauvais, F., Amara, J., Oberbaum, M., Robvizon, B., Miadonna, A., Tedeschi, A., Pomeranz, B., Fortner, P.,
Belon, P., Sainte-Laudy, J., Poitevin, B. & Benveniste, J. (1988). Human basophil degranulation triggered by very dilute
antiserum against IgE. Nature, 333, 816-818.
• Poitevin B, Davenas E, Benveniste J. In Vitro immunological degranulation of human basophils is modulated by lung
histamine and Apis mellifica. Br J Clin Pharmacol (1988); 25:439—44.
• Del Giudice, E., Preparata, G., Vitiello, G. Water as a free electric dipole laser. Physical Review Letters, 61, 1085. (1988)
• Citro M, Smith CW, Scott-Morley A, Pongratz W, Endler PC. Transfer of information from molecules by means of
electronic amplification. In: Endler PC, Schulte J, editors. Ultra high dilution: physiology and physics. Dordrecht
(Nederland): Kluwer Academic Publishers; (1994). 209-214.
• P.C. Endler. The effect of highly diluted agitated thyroxine on the climbing activity of frogs. Vet Human Toxicol 36(1).
(1994)
• Sainte-Laudy J, Belon P. Analysis of immunosuppressive activity of serial dilutions of histamine on human basophil
activation by flow cytometry. Inflamm Res (1996); 45(Suppl 1): S33–S34.
• P. C. Endler, W. Pongratz, C. W. Smith, J. Schulte, F. Senekowitsch, M. Citro. Non-Molecular Information Transfer from
Thyroxine to Frogs. Signals and Images (1997), pp 149-159
• Benveniste, J. et al. Transatlantic transfer of digitized antigen signal by telephone link. J. Allergy clin. Immunol., 99:s175
(1997)
• J. Benveniste, J. Aïssa, P. Jurgens,W. Hsue. Specificity of the digitized molecular signal. FASEB, (1998).
• Thomas Y, Schiff M, Belkadi L, Jurgens P, Kahhak L, Benveniste J. Activation of human neutrophils by electronically
transmitted phorbolmyristate acetate. Med Hypotheses (2000); 54:33-39.
Works that prove the existence of natural phenomena discovered by Jacques Benveniste

• E. B. Burlakova. Specific Effects of Superlow Doses of Biologically Active Substances and Low-Level Physical Factors.
Misaha Newsletter (2000): 390-424.
• Brown V, Ennis M. Flow-cytometric analysis of basophil activation: inhibition by histamine at conventional and
homeopathic concentrations. Inflamm Res (2001); 50(Suppl 2): S47–S48.
• Lorenz I, Schneider EM, Stolz P, Brack A, Strube J. Sensitive flow cytometric method to test basophil activation influenced
by homeopathic histamine dilutions. Forsch Komplementarmed Klass Naturheilkd (2003); 10: 316–324.
• Benveniste et al. Method, system and device for producing signals from a substance biological and/or chemical activity.
United States Patent # US 6,541,978 B1, (2003)
• Louis Rey. Thermoluminescence of ultra-high dilutions of lithium chloride and sodium chloride. Physica A, 323 (2003):
67-74.
• V. I. Korenbaum, T. N. Chernysheva, T. P. Apukhtina, S. N. Shin, V. N. Demenok. Effect of electronic homeopathic copy of
biohumus fertilizer on tomato sprout development. Radiative biology. Radioecology, (2003), 43, #3: 373-377.
• P.C. Endler. Pretreatment with Thyroxine (10-8 Parts by Weight) Enhances a 'Curative' Effect of Homeopathically Prepared
Thyroxine (10-13) on Lowland Frogs. Forsch Komplementärmed Klass Naturheilkd (2003);10:137-142
• Belon, P, Cumps, J, Ennis, M et al. Histamine dilutions modulate basophil activation. Inflamm res (2004);53:181-188.
• Benveniste, J., Guillonnet, D. Method and device for avoiding alteration of a substance having biological activity. US
Patent N◦ 0 038, 937 A1. (2004)
• P. Bellavite et al. Immunology and Homeopathy. 1. Historical background. Evidence-Based Complementary and
Alternative Medicine (2005). Vol.2(4):441-452
• Van Wijk R, Bosman S, van Wijk EP. Thermoluminescence in ultra-high dilution research. J Altern Complement Med
(2006); 12:437-443.
• Bellavite P. et al. Immunology and Homeopathy. 2. Cells of the Immune System and Inflammation, eCAM (2006);3(1)13–24

• P. Bellavite et al. Immunology and Homeopathy. 2. Cells of the Immune System and Inflammation. Evidence-Based
Complementary and Alternative Medicine (2006). Vol.3 (1):13-24
• A.L. Vereshchagin, T.L. Tsoi, V.V. Kropotkina. Application of ultra-low doses of biologically active substances and
homeopathic remedies in plant. Polzunovskiy vestnik (2006). 2: 343-348.
• Zhadin M. New ideas on structure of water and of aqueous solutions on the basis of modern quantum electrodynamics of
condensed matter as applied to biological and medical problems. New informational technologies in medicine, biology,
pharmacology and ecology, (2007) : 127-129
• S Weber, PC Endler et al. The effect of homeopathically prepared thyroxine on highland frogs: influence of electromagnetic
fields. Homeopathy (2008) 97, 3–9
• Butters. System and method for sample detection based on low-frequency spectral components. United States Patent: US
7,412,340 B2. (2008)
• E. Del Giudice, A. Tedeschi. Water and the autocatalysis in living matter. Electromagnetic Biology and Medicine. Vol. 28(1)
(2009).
• Chirumbolo S, Brizzi M, Ortolani R, Vella A, Bellavite P. Inhibition of CD203c membrane up-regulation in human basophils
by high dilutions of histamine: a controlled replication study. Inflamm Res (2009); 58: 755–764.
• Sainte-Laud J, Belon P. Inhibition of basophil activation by histamine: a sensitive and reproducible model for the study of
the biological activity of high dilutions. Homeopathy (2009); 98:186-197.
• I.S. Ryzhkina, L.I. Murtazina, E.D. Sherman, Yu.N. Valitova, E.A. Kataev, A.I. Konovalov, Low-concentration aqueous
solutions of macrocyclic pyridine-pyrrole compound: relationship between the parameters, physicochemical properties,
and physiological activity of supramolecular nanosized associates. Doklady Physical Chemistry, (2010), vol. 433, part 2, pp.
142-146.
• Benveniste, J., Benveniste L., Guillonnet, D. Method and system for producing a substance or a signal with a coagulating
or anticoagulant effect. US Patent N◦ 0 233, 296 A1 (2010)
• Benveniste, Ja., Benveniste Je., Benveniste V., Benveniste L., Benveniste C., Benveniste A. Method and system for
providing a substance with receptive and/or transmissive properties for a signal. US Patent N◦ 0 272, 629 A1 (2010)

• L Montagnier, J Aissa, E Del Giudice, C Lavallee, A Tedeschi and G Vitiello. DNA waves and water. Journal of Physics:
Conference Series 306 (2011) 012007.
• R. Miranda, A. Vannucci and W. M. Pontuschka. Impedance spectroscopy of water in comparison with high dilutions of
lithium chloride. Materials Research Innovations (2011), 15(5): 302-309.
• C. Takano, A. R. Miranda, A. Vannucci. Impedance Spectroscopy applied to the study of high dilutions of Lycopodium
clavatum. Int J High Dilution Res (2011) 10(36):101-103.
• Foletti A., et al. (2011) Differentiation of human LAN-5 neuroblastoma cells induced by extremely low frequency
electronically transmitted retinoic acid. JACM 17(8), 701-704.
• J.A. Heredia-Rojas, R. Gomez-Flores, A. O. Rodriguez-de la Fuente, E. Monreal-Cuevas, A. C. Torres-Flores, L. E.
Rodriguez-Flores, M. Beltcheva, A. C. Torres-Pantoja. Antimicrobial effect of amphotericin B electronicallyactivated water
against Candida albicans. African journal of Microbiology Research 6(15). (2012), pp. 3685-3689.
• L. Montagnier, C. Lavallee, J. Aissa. General procedure for the identification of DNA sequences generating electromagnetic
signals in biological fluids and tissues. US Patent N◦ 2012/0024701 A1. (2012)
• А. Foletti, M. Ledda, E. D'Emilia, S. Grimaldi, A. Lisi. Experimental Finding on the Electromagnetic Information Transfer of
Specific Molecular Signals Mediated Through the Aqueous System on Two Human Cellular Models. The Journal of
Alternative and Complementary Medicine. (2012), 18(3): 258-261.
• Foletti A. et al, Electromagnetic Information Delivery as a New Perspsctive in Medicine, PIERS Proceedings, Stockholm,
Sweden, Aug. 12-15, (2013)
• Demangeat JL. Nanosized solvent superstructures in ultramolecular aqueous dilutions: twenty years' research using water
proton NMR relaxation. Homeopathy (2013); 102:87-105.
• Currently HomBrex contains 2045 experiments published in 1518 original articles http://www.carstens-stiftung.de/
hombrex/index.php
Thus, hundreds of papers which represent researches in physics, biology, and
medicine, experimentally confirm the existence of the
phenomena discovered by Jacques Benveniste.

The damaging bureaucracy of academic peer review along with academic funding agencies should show support for
research in unfashionable fields. Support for research that might lead to advanced major scientific discoveries is virtually
forbidden nowadays. We call upon funding agencies to support sustained, open-ended research in unfashionable fields:
Donald W Braben, University College London; John F Allen, Queen Mary, University of London; William Amos,
University of Cambridge; Richard Ball, University of Edinburgh; Tim Birkhead, FRS, University of Sheffield; Peter
Cameron, Queen Mary, University of London; Richard Cogdell FRS, University of Glasgow; David Colquhoun FRS,
University College London; Rod Dowler, Industry Forum, London; Irene Engle, United States Naval Academy,
Annapolis; Felipe Fernández-Armesto, University of Notre Dame; Desmond Fitzgerald, Materia Medica; John Hall,
University of Colorado, Nobel Laureate; Pat Heslop-Harrison, University of Leicester; Dudley Herschbach, Harvard
University, Nobel Laureate; H Jeff Kimble, Caltech, US National Academy of Sciences; Sir Harry Kroto FRS, Florida
State University, Nobel Laureate; James Ladyman, University of Bristol; Peter Lawrence FRS, University of Cambridge;
Angus MacIntyre FRS, Queen Mary, University of London; John Mattick FAA, Garvan Institute of Medical Research,
Sydney; Beatrice Pelloni, University of Reading; Douglas Randall, University of Missouri; David Ray, Bio Astral
Limited; Sir Richard J Roberts FRS, New England Biolabs, Nobel Laureate; Ken Seddon, Queen’s University of Belfast;
Colin Self, University of Newcastle; Harry Swinney, University of Texas, US National Academy of Sciences; Claudio
Vita-Finzi FBA, Natural History Museum.
Link: The Telegraph, 02 Jun 2014
Presently, the phenomena discovered by Jacques Benveniste has begun
to garner much deserved attention and is need of further support from
fundamental researchers.

The above presented materials stand as a foundation for the justification of Jacques
Benveniste and his research discoveries. The biological and physical properties of water,
including the transfer of signals from biologically active substances are actual and
attested. The implications of this natural phenomena have vast applications in multiple
areas of human activity; and in particular, are already used in the fields of healthcare.
The Outstanding French Scientist was far ahead of his time and has made one of the
greatest scientific breakthroughs in recorded history. In the visage of our beloved
science, the time is now upon us to restore justice by giving tribute to a man who has
devoted himself wholeheartedly and suffered for his beliefs.
Please join us in our righteous efforts by signing onto our international initiative group.
Our main initiative is the restoration of the honest name Jacques Benveniste.
For contacts: Anton Fedorenko, faa@phystech.edu
Jeremy Pfeiffer, 369@svpwaterresearch.com
A portion of materials for this presentation is provided by the web-site of:
ASSOCIATION JACQUES BENVENISTE POUR LA RECHERCHE
International initiative to restore honest name of Jacques Benveniste