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OS16 - 4.P1.e Immune Responses to Foot-and-Mouth Disease Virus in Guinea Pigs After Vaccination with Canine Adenovirus Vector - S. Lacour

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OS16 - 4.P1.e Immune Responses to Foot-and-Mouth Disease Virus in Guinea Pigs After Vaccination with Canine Adenovirus Vector - S. Lacour

  1. 1. Open Session of the EuFMD - Cascais –Portugal 26-28 October 2016 S.A. Lacour, A. De Vleeschauwer, L. Bakkali-Kassimi, S. Zientara, K. De Clercq, B. Klonjkowski immune responses to foot-and-mouth disease virus in guinea pigs after vaccination with canine adenovirus vector ERA-NET ANIHWA
  2. 2. Transfection of DKE1 cells CAV-P1/3C CAV-P1-3C Human adenovirus Canine adenovirus P1
  3. 3. OS16 Assessment of protection Immune response viremia Clinical symptoms
  4. 4. OS16 CAV2-based vector can - express immunogenic FMDV antigens in rodents, - provide protection against FMD in guinea pigs - and suggest that CAV-P1/3C could be a potential marker vaccine against FMD Conclusions

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