1.
Open Session of the EuFMD - Cascais –Portugal 26-28 October 2016
Horizontal transmissibility of the foot-and-mouth
disease virus O/JPN/2010 among different species
of animals
K. Fukai, T. Nishi, N. Shimada, K. Morioka, M. Yamada, K. Yoshida, R. Kitano, R.
Yamazoe, M. Yamakawa
Exotic Disease Research Station, National Institute of Animal Health, National Agriculture
and Food Research Organization, Japan

2.
OBJECTIVE
• Horizontal transmissibility of the foot-and-mouth disease virus (FMDV)
O/JPN/2010, which was isolated in the 2010 epidemic in Japan, has been analysed
among the same species of animals such as cows, goats and pigs in our previous
studies.
• The O/JPN/2010 transmitted horizontally to the same species of all contact animals.
• In this study, horizontal transmissibility of the O/JPN/2010 among the different
species of animals was analyzed in order to elucidate difference of transmission
situations of FMDV among the same and different species of animals.

3.
RESULTS
Experimental
designs
Inoculated
animals
Contact
animals
Rates of horizontal
transmission
Average days when antibodies were
initially detected in contact animals
Cow Cow 100% 6.0
Goat Goat 100% 7.5
Pig Pig 100% 4.0
Cow Goat 75% 6.3
Cow Pig 75% 7.3
Goat Cow 50% 9.0
Goat Pig 0% Not available
Pig Cow 100% 8.5
Pig Goat 100% 7.3
Experimental infections among the same species of animals
Experimental infections among different species of animals

4.
DISCUSSION
• Horizontal transmission of the O/JPN/2010 occurred completely among the same
species of animals; however, the transmission did not occur completely among the
different species of animals in this study, especially from the goats to the cows and
pigs.
• Appearance of vesicular lesions may be involved in horizontal transmissibility of the
O/JPN/2010 in animals because the lesions in the inoculated cows and pigs were
more apparent than those in the inoculated goats.
• However, goat-to-goat transmission occurred completely in our previous study;
therefore, any other factors may influence horizontal transmissibility of FMDV
among the different species of animals.