1.
www.pirbright.ac.ukThe Pirbright Institute receives strategic funding from BBSRC.
Antigenic and genetic
characterization of FMDV serotype O
circulating in South East Asia
S. Upadhyaya, M. Mahapatra, S. Aviso, G. Hutchings and S. Parida
Vaccine Differentiation Group

2.
FMD: South East Asia
• Economically important livestock disease -global distribu7on
• Endemic in Asian con7nent including South East Asia
• Three of the seven known FMDV serotypes (A, O, and Asia 1)
are circula7ng in South East Asia
• Most of the outbreaks are caused by serotype O (>60%)
• Three different topotypes circula7ng in SEA countries (SEA,
Cathay and ME-SA)
• SEA: Mya-98 lineage viruses, ME-SA: PanAsia viruses
• Recently Ind2001d lineage - Lao PDR, Myanmar, Vietnam

3.
FMD - South East Asia
SEA
ME-SA
Cathay
Virus (n=97) 2007-2012
Vaccine (n=5)
SEA: 2
ME-SA: 2
Cathay: 1
Capsid sequences
Serology: 2D-VNT

4.
VNT results
Best vaccine: PanAsia-2
r1-values
No. of isolates

5.
Acknowledgements
www.pirbright.ac.ukThe Pirbright Institute receives strategic funding from BBSRC.
The Pirbright InsNtute
Aravindh Babu
Nigel Ferris
WRL FMD
Nico Visser
Danny Gooverts
IIL, India
V A Srinivasan
M Madhan Mohan
PD-FMD, India
B PaXnaik
Murdoch Univ, Australia
Ian Robertson