Granulation Process

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An introduction in granulation

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Granulation Process

  1. 1. Granulation <ul><li>done to </li></ul><ul><ul><li>improve flow properties of the mix </li></ul></ul><ul><ul><li>improve compression properties of the mix </li></ul></ul><ul><ul><li>prevent segregation of components in powder mix </li></ul></ul><ul><ul><li>reduce production of toxic dust </li></ul></ul><ul><ul><li>reduce possibility of ‘cake’ formation </li></ul></ul><ul><ul><li>increase convenience of transport </li></ul></ul>
  2. 2. Granulation <ul><li>particle bonding mechanisms </li></ul><ul><ul><li>adhesion and cohesion forces in immobile liquid films </li></ul></ul><ul><ul><li>interfacial forces in mobile liquid films </li></ul></ul><ul><ul><li>solid bridges </li></ul></ul><ul><ul><li>attractive forces between solid particles </li></ul></ul>
  3. 3. Granulation <ul><li>Wet granulation equipment </li></ul><ul><ul><li>3 main types </li></ul></ul><ul><ul><ul><li>shear granulators </li></ul></ul></ul><ul><ul><ul><li>high speed mixer/granulators </li></ul></ul></ul><ul><ul><ul><li>fluidized bed granulators </li></ul></ul></ul><ul><ul><li>shear granulator </li></ul></ul>
  4. 4. Wet Granulation <ul><ul><li>high speed mixer/granulator </li></ul></ul>
  5. 5. Wet Granulation fluidized bed granulator
  6. 6. Wet Granulation <ul><ul><li>other more specialized granulators </li></ul></ul><ul><ul><ul><li>spray driers </li></ul></ul></ul>
  7. 7. Wet Granulation <ul><ul><li>pelletizers </li></ul></ul>
  8. 8. Dry Granulation <ul><li>Dry granulation equipment </li></ul><ul><ul><li>sluggers </li></ul></ul><ul><ul><li>roller compactors </li></ul></ul>

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