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RADICAL 
LONGEVITY 
GENOMIC 
MEDICINE 
YOU 
STEVEN TUCKER, MD, FACP, FAMS 
Global Health Advisor, SingTel 
Founder, Tucker Medical
WORD OF 
CAUTION 
We tend to overestimate 
the effect of a technology 
in the short run and 
underestimate the effect 
in the long run. 
Roy Amara 
Co-founder, Institute for the Future
1 
EXPONENTIALS
4E+09 
3E+09 
2E+09 
1E+09 
4E+03 
COMPUTING 
POWER 
1974 1984 1994 2004 2014 2024
4E+09 
3E+09 
2E+09 
1E+09 
4E+03 
MOORE’S 
LAW 
1974 1984 1994 2004 2014 2024
Sensors 
4E+09 
3E+09 
Laboratory 
2E+09 
1E+09 
4E+03 
MOORE’S 
LAW 
3D Printing 
Genomics 
1974 1984 1994 2004 2014 2024
2 
SENSORS
SENSOR 
EVOLUTION 
Sensor 1.0 
Sensor 2.0 
Sensor 3.0 
Ability to measure 
+ record signal 
Sensor web 
integration; share 
+ access data 
Passive data 
gathering + 
aggregating + 
meaningful insight
ACTIVITY 
TRACKING
HEALTH 
TRACKING
MEDICAL 
TRACKING
EMERGENCY
STAR TREK 
TRICORDER
VITAL SIGNS
PACEMAKERS
CARDIAC MONITOR
DIABETES PUMP
WIRELESS 
BIRTH CONTROL
SMART PHONES
SENSORS 
Gyroscope 
Gesture 
Ambient light 
Heart rate 
Accelerometer 
Proximity 
Compass 
Barometer 
Fingerprint 
Hall cover
3 
LABORATORY
SHRINK THE LAB
THERANOS
RETAIL LABS
HOME TRACKING
HOME DIAGNOSIS
HOME DIAGNOSIS
LAB ON A CHIP
LAB ON A CHIP 
LEGO-STYLE
CELL CAPTURE
LIQUID BIOPSY
SMART PHONE 
THERMAL CYCLER
4 
3D PRINTING
MAKERBOT
MAKERBOT
-R- 3DS US
WORD OF 
CAUTION 
We tend to overestimate 
the effect of a technology 
in the short run and 
underestimate the effect 
in the long run. 
Roy Amara 
Co-founder, Institute for the Future
TITANIUM 
LOWER JAW
FACE 
TRANSPLANT
NOSE + EAR
PROSTHETIC LIMBS
WORD OF 
CAUTION 
We tend to overestimate 
the effect of a technology 
in the short run and 
underestimate the effect 
in the long run. 
Roy Amara 
Co-founder, Institute for the Future
3D PRINTED MEAT
MEAT MARKET
5 
GENOMICS
GENOME 
The collective noun for an 
organism’s hereditary 
information
DNA
GENOME MATH 
23Pairs of 
chromosomes
GENOME MATH 
20k Genes
GENOME MATH 
4Bases 
A - T 
G - C
GENOME MATH 
3.2 
Base pairs 
per genome 
billion
GENOME MATH 
3.2billion 40xCoverage BP 128billion 
data points
SEQUENCING $
GENOMICS 2001
GENOMICS 2007
GENOMICS 2013
GENOMICS 2014
GENOMICS 2014
GENOMICS 2016
GENOMICS 2018
NEXT GEN 
SEQUENCING
NEXT 
NEXT GEN 
SEQUENCING
NIPT
NIPT
NIPT
GENETIC FEAR
GENE EDITING 
CRISPR - 2010
BACTERIA
MICROBIOME
MICROBIOME 
100,000,000,000,000
MICROBIOME
MICEpRigOenBoImOeME 
Microbiome 
The ecological community of 
commensal, symbiotic, and 
pathogenic microorganisms that 
literally share our body space.
D 
AT 
A 
D 
AT 
A 
D 
AT 
A 
D 
AT 
A 
D 
AT 
A
Epigenome 
EPIGENOME 
DNA 
The record of the chemical changes to 
the DNA of an organism. Changes to 
the epigenome can result in changes 
to the function of the genome.
PREpOigTeEnoOmMeE 
Proteome 
The collective set of proteins 
expressed by a genome, cell, 
tissue or organism at a certain 
time.
EXEpPigOeSnoOmMeE 
Exposome 
28 33 
48 
Cd 
80 
Ni 
81 
82 
Ti 
The collective measure of the 
effects of life-long environmental 
exposures on health 
Hg 
Pb 
As
PEHpiEgNenOomMeE 
Phenome 
The collective noun for an individuals 
expressed phenotypic traits such as 
height, skin colour, body 
composition, and even personality.
Digital Health as 
Google Map 
HEALTH AS A 
GOOGLE MAP 
SENSOR 
ACTIVITY 
DIET 
GENOME 
MICROBIOME 
LAB 
PHENOME 
UNIQUE 
PERSON
6 RADICAL 
LONGEVITY
LIFE EXPECTANCY
LIFE EXPECTANCY
2050: TRIPLE THE 
NUMBER > 80
LONGEVITY USA
LONGEVITY USA 
3m/Yr
LONGEVITY GAP
TECHNOLOGY 
COMPANIES
BIOLOGY 
COMPANIES
CALICO
HUMAN LONGEVITY
GENETIC CODE
COMPUTER CODE
4E+09 
3E+09 
2E+09 
1E+09 
4E+03 
EXCEEDING 
MOORE’S LAW 
1974 1984 1994 2004 2014 2024
4E+09 
3E+09 
2E+09 
1E+09 
4E+03 
EXCEEDING 
MOORE’S LAW 
Genomics 
Robotics 
Nanotech 
Exceed 3m/yr 
1974 1984 1994 2004 2014 2024
IMMORTALITY ?
LIFESPAN
HEALTHSPAN
THANK YOU 
For your 9me & a>en9on
www.TuckerMedical.com 
@drsteventucker

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