Welcome. Thanks for coming out this evening. Self intro.On the surface, the topic tonight is digestion. But the real goal of this presentation is to elaborate on the interconnections between digestion and chronic disease, and on whole health strategies that healthcare practitioners can deploy to address not only the mild digestive complaints that frequent the aging gut, but also to look at how the restoration of digestive function is at the core of restoring health of the whole person. Anti-aging is a popular category these days. But what does it really mean?
Also BioZyme:Two tablets before each meal.Pancreatic enzymes 10X††325mg*Trypsin75 mg*Papain50 mg*Bromelain (2,400 G.D.U./g)16mg*Amylase10 mg*Lipase10 mg*Lysozyme (egg)10mg*Chymotrypsin2 mg
Inside the body, the low pH of the gastric environment and exposure to stomach acid are the primary factors that can kill of viable probiotic cultures.First generation pharmaceutical enteric coatings utilized chemicals that, while effective, were unsuitable for “natural” products.Advances in formulation technology now allow for precise protection and dissolution of natural “enteric” coatings incorporating ingredients such as gelatin, pectin and lecithin.
So we have a tendency to think that if a little is good, then more is better. Well, you know and I know that is not always true. There is a therapeutic window for most herbs and nutritional supplements and certainly for drugs, so why should it be different for probiotics. And yet when you look where some of the research is going, and when you look at products on shelves, we’re seeing formulations with absolutely massive numbers of CFUs.5 billion isn’t enough, we need 10 billion, 20, 30 60 billion and up. We have adopted what, in my opinion, is a very ham-handed more-is-better approach to probiotics supplementation. This has happened in large part, I think, because the sophistication of the topic does not lend itself to easy product differentiation in terms of labeling and marketing and competition. A consumer is not likely to enough knowledge to recognize a thoughtfully formulated product. Heck, even most physicians don’t know enough. The industry itself doesn’t know enough. And so we go with what we know. We can put more. People understand more. Their product has 10m billion CFU, well, we’re putting in 25 billion for the same price. Person looking at the label thinks that’s a stronger or more efficacious product, more bang for the buck.Well this is a big mistake. You wouldn’t treat an iron supplement that way. These are live organisms, and they exist in a delicate balance in elaborate communication with our immune system. Does it really make sense to inundate our bodies with huge numbers of CFU of one or two strains. How does that restore balance to this system? In fact, if you look at some of the research, by researchers like Dr. IichirohOhhiria, you find that this strategy can backfire, that inundating the system in this way can actually activate T and B cells in a way that resembles how they would fight bad bacteria.
Outside the body, exposure to heat, light and oxygen are the primary factors that destroy viable probiotic bacteria.
Delivered by Corey B. Schuler, DC, MS, CNS, LN for Emerson Ecologics Product Knowledge Training<br />Restoring Digestive Vitality<br />
Optimize digestion<br /> Reduce intestinal permeability<br /> Support elimination for mild cleansing and detox<br /> Re-establish a healthy balance of intestinal microflora<br />Restore Digestive VitalityFour Steps<br />
Cellulase 350 CU</li></ul>Because pH abnormalities may <br />accompany aging in the gut, formulation <br />should have documented activity across a <br />broad pH range.<br /> Nat Med J 2010 March;2(3):14–23.<br />
SimilaseProduct Code: SIMIL (90 caps)Product Code: SIMI2 (180 caps)<br />Proprietary digestive enzyme formula active across a broad pH range.<br />High potency, vegetarian formula<br />Broad spectrum activity<br />Relieves occasional gas, bloating, and indigestion.<br />Superior support of carbohydrate, protein, fat, and fiber digestion.<br />
Gluten<br />A combination of gliadin and glutenin proteins found in grass-related grains, like wheat, barley, and rye<br />Oatmeal is sometimes linked to gluten intolerance, but the latest consensus is that oatmeal doesn’t contain gluten, but may be contaminated during processing<br />Common in bread, pasta, and cereal<br />Hidden sources<br />Salad dressing<br />Cold cuts<br />Frozen yogurt<br />Toothpaste<br />Gum <br />Envelopes<br />
Casein<br />A protein found in dairy products<br />Common in milk, cheese, and yogurt<br />Not same as lactose (milk sugar)<br />Hidden sources<br />Margarine<br />Caramel or butter flavoring<br />Deli meats<br />Jelly beans<br />Some fast food <br />French fries<br />
Similase GFCFProduct Code: SIM1<br />Broad-spectrum enzymes to promote complete digestion of fats, carbohydrates, fiber, and protein <br />Active across a wide pH range<br />Includes Dipeptidyl Peptidase IV (DPP IV) to digest hidden gluten and casein in the diet.<br />
Optimize Digestion<br />If pancreatic enzyme support is required, consider:<br />Two-phase, chemical-free combination<br />Hydrochloric acid (e.g., Betaine HCl, Glutamic acid HCl) and/or Pepsin (1:3000)<br />Pancreatin<br />Lipase (2,000–14,000 USP units TID)<br />Amylase (25,000–180,000 USP units TID)<br />Protease (25,000–180,000 USP units TID)<br />Ox bile extract 65–130 mg TID with meals<br />Pancreatic enzymes should be formulated in a delayed-release matrix to prevent deactivation of enzymes by stomach acids.<br />
Panplex 8Product Code: PAN66 (60 tabs)<br />High potency pancreatin, an enzyme complex containing protease, amylase, and lipase<br />8 times stronger than the minimum activity specified by the USP.<br />Helps digest the full range of food types, including fats, carbohydrates and proteins.<br />Formulated for release in the intestines where optimal benefits occur.<br />
Panplex 2-PhaseProduct Code: PAN64 (60 tabs) Product Code: PAN65 (180 tabs)<br />Dual-action formula provides support for gastric and intestinal phases of digestion.<br />Phase I support provides hydrochloric acid (HCl), from betaine HCl and L-glutamic acid HCl, and the protein-digesting enzyme, pepsin for release in the stomach.<br />Phase II ingredients include high potency pancreatin and bile salts in a unique, chemical-free delayed-release matrix.<br />
Permeability FactorsProduct Code: PERM4 (90 softgels)<br />Clinically studied nutrients, phospholipids, and essential fatty acids provide nutritional support for intestinal mucosa <br />Contains a high level of glutamine – clinically shown to support healthy intestinal barrier function.<br />Standard of care for many naturopathic physicians<br />Gluten free formula – ideal for those with food sensitivities.<br />
RhizinateProduct Code: RHIZIRhizinate Sugarless Product Code: RHIZ4 Rhizinate 3X Product Code: RHIZ45<br />Glycyrrhizic acid-free formula provides only the beneficial effects of licorice<br />Chewable formula works naturally with enzymes in saliva to support digestive health<br />Best tasting DGL; 3X has delicious German-chocolate flavor<br />Helps relieve stomach discomfort by stimulating and accelerating natural protective factors in the digestive tract<br />Boosts the production of mucin, a natural compound that coats and protects the lining of the stomach and intestines<br />3X is a potent 10:1 extract; provides immediate benefits and maximum absorption in chewable form.<br />Includes glycine to help keep the stomach lining strong.<br />
Step 3: Support elimination for mild cleansing and detox<br />
Blue HeronProduct Code: BLU12 (120 caps)<br />Gluten-free blend of dietary fiber, nutritional herbs, and probiotic microflora for convenient, effective, and gentle intestinal support<br />Four unique sources of fiber<br />Flax, psyllium, driedplum, rice bran<br />Soothing GI blend<br />Marshmallow, slippery elm root, fenugreek<br />Detoxification<br />Triphala<br />Microflora support<br />Probiotics<br />Enzymes<br />Papain<br />
Step 4: Re-establish a healthy balance of intestinal microflora<br />
Effects of Probiotics<br />Probiotics decrease intestinal inflammation and enhance mucosal integrity <br />Normalizes gut permeability<br />Probiotics lessen systemic antigenic exposure and allergic sensitization <br />Non-allergic children have higher concentrations of Lactobacilli and Bifidobacteria<br />Probiotics increase local immune activity <br />IgA, GALT, IFN<br />Probiotics modulate systemic immune activity<br />
Viability of commercial preparations<br />Studies have shown low viability of Lactobacilli and Bifidobacteria in unprotected commercial preparations.<br />This has led to the development of various strategies to preserve viability of supplemental probiotics.<br />Immunol Cell Biol. 2000 Feb;78(1):80-8.<br />JDairySci. 2000 Apr;83(4):894-907.<br />Curr Issues IntestMicrobiol. 2004 Mar;5(1):1-8.<br />
Inspecting the label<br />CFU = colony forming units<br />High number of CFU does not necessarily indicate a better or more effective product<br />Evaluate genus and species for appropriate applications<br />Evaluate adjunctive ingredients (e.g., lactoferrin, FOS)<br />Number of CFUs should be based on expiration date, not on date of manufacture.<br />
What’s important in a Lactobacillus?<br />Adhere to cells<br />Exclude or reduce pathogenic adherence<br />Persist and multiply<br />Produce acids, hydrogen peroxide, and bacteriocins antagonistic to pathogen growth<br />Resist vaginal microbicides, including spermicide<br />Be safe and therefore noninvasive, non-carcinogenic, and nonpathogenic<br />Co-aggregate and form a normal, balanced flora.<br />Appl Environ Microbiol1999;65(9):3763-6.<br />
Packaging and Viability<br />“Pick quality packaging and a trusted manufacturer.”<br />“Live bacteria — through the end of shelf life.”<br />“Packaging should ensure an effective level of live bacteria through the ‘best by’ or expiration date.”<br />International Scientific Association for Probiotics and Prebiotics<br />
Probiotic Pearls Product Code: PRO74 (30 pearls) Product Code: PRO73 (90 pearls)<br />Provides 1 billion CFU of a blend of Lactobacillus acidophilus and Bifidobacteriumlongum.<br />True Delivery Technology<br />Ensures Active Cultures <br />SURVIVE<br />ARRIVE<br />THRIVE<br />Guaranteed Delivery<br />Shelf-stable<br />No refrigeration required<br />Hardy strains<br />
Probiotic Pearls ADVANTAGEProduct Code: PR131 (60 pearls)<br />Provides 5 billion CFU of an exclusive blend of Lactobacillus (L. plantarum,L. acidophilus) and Bifidobacterium (B. lactis, B. longum).<br />True Delivery Technology<br />Ensures Active Cultures <br />SURVIVE<br />ARRIVE<br />THRIVE<br />Guaranteed Delivery<br />Shelf-stable<br />No refrigeration required<br />Hardy strains<br />