Successfully reported this slideshow.
We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. You can change your ad preferences anytime.

Cold chain tot

340 views

Published on

Published in: Education
  • ALL THANKS TO DR WILLIAMS I was diagnosed of hepatitis B in 2011, I have tried all possible means to get cure but all my effort proved abortive, until a friend of mine introduced me to a herbal doctor , who prepare herbal medicine to cure different kind of diseases including hepatitis b virus (HBV), when i contacted this herbal doctor via his email, he sent me hepatitis b herbal medicine via courier service, when i received the herbal medicine he gave me step by step instructions on how to apply it, when i applied it as instructed i was totally cured from this virus within 8 days of usage. any body with similar problem can Contact this great herbal doctor via his email drwilliams098675@gmail.com for advice and for his product .and thanks to you admin for such an informative blog.
       Reply 
    Are you sure you want to  Yes  No
    Your message goes here

Cold chain tot

  1. 1. Cold Chain – An Overview 1www.drjayeshpatidar.blogspot.in
  2. 2. Cold Chain is a system of transporting and storing vaccines at recommended temperature from the point of manufacture to the point of use Definition 2www.drjayeshpatidar.blogspot.in
  3. 3. Essential Elements of Cold Chain  PERSONNEL to organize and manage vaccine distribution  EQUIPMENT for storage and transport of vaccines.  Transport facilities  Maintenance of equipment  Monitoring 3www.drjayeshpatidar.blogspot.in
  4. 4. In general • All Vaccines tend to lose potency on exposure to heat above +80 C • Some Vaccines lose potency when exposed to freezing temperatures • The damage is irreversible 4www.drjayeshpatidar.blogspot.in
  5. 5. OPV Measles BCG Vaccines sensitive to heat 5www.drjayeshpatidar.blogspot.in
  6. 6. Hep- B DPT DT TT Vaccines sensitive to freezing 6www.drjayeshpatidar.blogspot.in
  7. 7. Ice lined refridgerators (ILRs) •Capacity: 140 litres at PHC level(1200 vials) •Ideal Temperature: +2 C to 8 C (Effective with electricity supply of 8/24 hrs) •Safe Storage: Always in the basket section (Always T series, Hepatitis-B and Diluents) (OPV/Measles/BCG may be kept below basket in case space is not available) •Thermometer: Place in the ILR-basket 7www.drjayeshpatidar.blogspot.in
  8. 8. Right way of keeping vaccines in ILR • Keep all vaccines in baskets • Place a thermometer in the center of the ILR. • Avoid placing vaccines at bottom of ILR. (never diluents, freeze sensitive) • Leave space between the vaccine boxes • Same vaccines in same area. • Diluent / freeze sensitive/ Closer expiry date vaccines on top • Heat sensitive / Further expiry date vaccines in the bottom of basket 8www.drjayeshpatidar.blogspot.in
  9. 9. Deep freezers (DF) • Capacity: 140 litres at PHC level • Ideal Temperature: -18 C to -20 C (In case of power failure - maintain temperature for 18-20 hrs) • Ice Pack Freezing Capacity: freezes 20 ice packs every 24 hours. 9www.drjayeshpatidar.blogspot.in
  10. 10. Cold Boxes • Type: Insulated boxes of 5 litre capacity • Usage: Stores & transports vaccine. Also stores frozen Ice Packs • Capacity: 1500 doses (mixed antigen) or 5000 doses (only OPV) with 24 ice packs. • Holdover Time:3 days (Keep thermometer inside) • Vaccine Layout: Direct contact of frozen Ice packs spoil the vaccine. Give carton spacers/surround vaccine by OPV vials. • Label Protection: Place vaccine in cartons or polythene bags. 10www.drjayeshpatidar.blogspot.in
  11. 11. Vaccine Carrier • Type: Insulated boxes used for carrying small quantities of vaccine. • Capacity: 16-20 vials • Holdover Time: Maintain +2 to+80 C for about 24 hours (one day) • Ice packs: A maximum of 4 frozen packs • Vaccine Layout: Keep vaccines in a plastic bag (not in direct touch with the Ice packs) 11www.drjayeshpatidar.blogspot.in
  12. 12. Ice Packs Water Fill: • Do not fill 100%. • Leave 10 mm room for expansion as water freezes. • Close the cap tightly • Clean the outer surface dry before freezing 12www.drjayeshpatidar.blogspot.in
  13. 13. Ice Pack Freezing • Ice Packs to be frozen ROCK Solid • Freezing is faster & uniform if gap /breathing space is left between ice packs • Ice Packs are best frozen in Deep Freezers • Condition before use 13www.drjayeshpatidar.blogspot.in
  14. 14. Preparing icepacks for use: Conditioning A Conditioned ice-pack •On the session day, take the frozen ice-packs you need from the freezer and place on a table •Allow ice-packs to sweat (droplets of water) at room temperature •Shake the ice pack to listen to sound of water. 14www.drjayeshpatidar.blogspot.in
  15. 15. Maintenance of Equipment • Defrosting/Cleaning: Ice deposit 5mm & over in freezer or at the bottom of ILR results in rise in temperature. Periodic defrosting & cleaning ensures trouble free performance for a long period. • Cold boxes/Vaccine Carriers: Cold box hinges, lid knobs & chains are often damaged. Replace or repair locally. Minor insulation casing cracks/gaps can also be repaired with fresh PUF insulation • Ice Packs: Fill clean water for freezing & leave 10mm room for expansion as water freezes. Cap tightly to avoid leakage. Keep pack clean & dry. 15www.drjayeshpatidar.blogspot.in
  16. 16. Vaccine Distribution • Follow first-in-first - out rule (FIFO) • Also: first to expire - first out. (FEFO) • Vaccines are not stored at the sub-centre level and must be supplied on the day of use • Note manufacturer, batch no, VVM status • Use VVM stage-II vaccine near the cold chain point (do not distribute to remote areas) 16www.drjayeshpatidar.blogspot.in
  17. 17. Storage Temperature • Monitor temperature twice daily. • All vaccines at PHC are stored between +2 to+8 C 17www.drjayeshpatidar.blogspot.in
  18. 18. Shake test Shake the control and test samples • Hold the Control and the Test sample together in hand and vigorously shake the samples • Place both vials to rest on a flat surface, side-by-side observe them for 30 minutes. • Compare for rate of sedimentation USE TestControl Test Control Discard 18www.drjayeshpatidar.blogspot.in
  19. 19. Shake Test: Summary 19www.drjayeshpatidar.blogspot.in
  20. 20. Vaccine Vial Monitor 3 = bad: Don’t Utilize 4 = bad: Don’t Utilize The central square is equal to, or darker than the surrounding circle X X 1 = good: Utilize 2 = good: Utilize The central square is lighter than the surrounding circle 20www.drjayeshpatidar.blogspot.in
  21. 21. Potency • T series, Hep B and diluents should never be frozen. • BCG, OPV & Measles are sensitive to heat and light & lose potency fast. • Potency lost due to heat exposure does not change the appearance of the vaccine. • VVM is an effective tool in monitoring OPV potency. • Damage to vaccine cannot be reversed by re-freezing. • Discard frozen vaccine. 21www.drjayeshpatidar.blogspot.in

×