Mtdc -‐mtcp technology commercialization workshop for start-


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Mtdc -‐mtcp technology commercialization workshop for start-

  1. 1. The Age of Wellness Presentation by Dr. Amr M. Helal Founder and CEO of Health Tech The new definition for WWW 24 Abo El-Mahassin El Shazely Street, Gize POC 12411 Egypt Tel. 00202 33458525 Fax 00202 33477755 Email web site
  2. 2. Agriculture and Food industries waste materials a)Rice bran: more than 500 000 MT/year get rancid and used as animal feed. a) Orange peel: Egypt is ranked number 4 world wide, number 9 in orange juice export and yet Egypt is not in the market of pectin (460 Million US$/ year) but pectin importing country (One ton peel@US$7 contain 200 Kg pectin@US$12/kg c) Olive leaves, grape seeds, pomegranate peel, artichoke leaves
  3. 3. Health tech is a start up company investing in science of nutraceuticals and functional food It is here where an UNTOLD WEALTH of vitamins, minerals and bioactives (CVD, DM type II, elevated Cholesterol levels, Anti inflammatory & Hypertension and . However due to non stabilization of Rice Bran it is still discarded or used as animal feed despite its high content of bioactive substances
  4. 4. Previous Projects Industrial Modernization Centre Fund (IMC) o o o Phytochemical Study of SRB of budget 200,000 L.E Implementation of SRB in food, pharmaceutical & cosmetic products of budget 100,000 L.E Rice Bran Stabilization Pilot Unit, of budget 700,000 L.E (local patent submission) European-Egyptian Innovation Fund (EEIF) o Developing Egyptian Nutraceutical Rice Bran with a total budget of 192500 EURO (trade secret !!) Research Partners: (Business growth from their trust) o o o o o o o National Research Centre, Egypt Faulty of Agriculture, Mansoura University Faculty of Pharmacy Cairo University Faculty of Pharmacy, Coethe Universitat, Frankfurt, Germany Faculty of Pharmacy, German University VivaCell Biotechnology GmBH BasPharma, The Netherlands
  5. 5. A letter worth EURO 100000
  6. 6. * Comparative Study on Egyptian Rice Bran Extracted by Solvents and Supercritical CO2. Advances in Food Sciences, 35 (1), 2013, 23-29. (Germany). * Egyptian rice bran oil: chemical analysis of the main phytochemicals. La Rivista Italiana delle Sostanze Grasse in 25 January, 2013 (Italy). * Chemical, Rheological, Sensorial and Functional Properties of Gelatinized Corn- Rice Bran Flour Composite Corn Flakes and Tortilla Chips, Journal of Food Processing and Preservation, 2012 (Wiley) * Rice bran oil: Preparation and evaluation of novel liquisolid and semisolid formulations. International Journal of Pharmaceutical compounding, * Rice bran solid lipid nanoparticles: Preparation and characterization Mohamed International Journal of Research in Drug Delivery Universal Research Publications
  7. 7. Potential Health Benefits *Developing a nutraceutical from Egyptian Stabilized rice bran: pharmacological approach PlantaMed 2011:77: 1229-1472 *Antidiabetic effects of a standardized Egyptian rice bran extract. Phytother Res. 2013 *Rice bran extract protects from mitochondrial dysfunction in guinea pig brains. Pharmacol Res. 2013
  8. 8. * Rice bran oil has a composition of Fatty acid C14:0 C16:0 C18:0 C18:1 C18:2 C18:3 Myristic acid Palmitic acid Stearic acid Oleic acid Linoleic acid α-Linolenic acid % 0.6% 21.5% 2.9% 38.4% 34.4% 2.2%
  9. 9. Fatty Acid Percentage Lauric C12 4.09 Myristic C14 1.60 Palmitic C16 1.02 Stearic C18 10.32 Palmitoleic C16:1 Linoleic C18:2 29.07 Linoelaidic C18:2 3.70 α-linolenic γ-linolenic C18:3(γ) C18:3(α) 35.79* 6.36 Saturated Fatty Acids 17.03 Unsaturated Fatty Acids 74.92 Table 4.4: GLC analysis of fatty acids content of rice bran hexane extract (as percentage of total saponifiable matter):
  10. 10. A. Stabilized Rice Bran Extract with scientific evidence of potential activity (EURO 100/kg). B. Stabilized Rice bran Extract in Soft Gel capsules Riciples (MOH registration , year 2 (24 capsules (12gm), retail price at EURO 3.5). C. Oryza ( 30 sachets (150 gm.) at EURO 3.
  11. 11. Diabetic patients (as food supplement) 10 % of Egyptian are diabetics Roughly 9 million patients with1% of them has daily Supplements of Vit. E and others. Riciplex is targeting 10 % of this segment Estimated market is LE 3,780,000 By the end of 2014, the vitamins and minerals category will be worth EGP761.9m ($140.3m), with an expected CAGR of 6.2% between 2009 and 2014.
  12. 12. Aged population A crude prevalence rate of dementia of 3.66%, (1.4% for Alzheimer's disease 3.1 Million Egyptians are suffering from dementia, of them 1.2 Million Egyptian is suffering (AD). This means at least about from AD as a very conservative figure. Riceplex and Oryza are very competitive supplements compared to other ones.
  13. 13. Stunted children (under 5) and malnutrient school students (6-12) (three years plan) Where Does Egypt Stand? • 29% of children under the age of five are stunted, 6% are underweight, and 7% are wasted. ‫التعلين تقزر استخذام ردة األرس في التغذية المذرسية‬ El Destor news paper Wednesday 11.12.2013 The school nutrition program is currently 450 Million and planned to reach LE 3 Billion in 3 years
  14. 14.
  15. 15. Riciplex and Oryza (supplements) Pharmaceuticals supply chains with (20% retail discount, 12 % marketing cost, 10 % marketing aids) Raw Stabilized Rice Bran Food ingredient in school nutrition program ( supplier to Manufacturers; our registered formulations based on rice bran) Stabilized Rice Bran Extract Energy food and beverage ingredients International Exhibition (e.g, VITAFOOD, Gulf Food)
  16. 16. - Spin off from a company of 25 years experience. - 75% of share holders and managers are under 35 - Unique vision of Industry and Market driven R&D development - Established EU and Egyptian (and hopefully Malaysian through MTDC) multi sectorial high ranked researchers
  17. 17. National and Int’l MEDIA COVERAGE
  18. 18. Now, Dr. Amr Helal, a pharmacist and company founder in Cairo, developed a new method to stabilize the rice bran which opens many new possibilities to use it. Together with different researchers in Egypt and Germany, he started to analyze the impact of rice bran on the human health and the progress of different diseases. The Goethe University in Frankfurt is one of the partaking research institutions. There, the scientists are testing the effects of eating rice bran particularly on Alzheimer’s and high blood pressure using mice as an indicator.
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  20. 20. 2014- 2016 Pilot production of pectin from orange peels Short listed for acceptance for R&D project lE 1 Million Orange Production in Egypt -Production: -Fresh orange (3.5 million MT in 2012)  ranked # 6 in the world -Export: -Fresh orange (> one million MT in 2012)  ranked #4 in the world -Orange Juice (3000 ton in 2012)  ranked #19 in the world) -Domestic use  > 2 million MT in 2012 -Waste “Orange peel”  >40% of orange wt. Orange peel  contain > 20% pectin - Pectin production in Egypt  ZERO
  21. 21. Research Funds A- Fund for R&D in rice bran - EURO 100 000 (approved) - EURO 250 000 (recipe for stunt fight, submitted) - EURO 1 Million (recipe for aged population ; to be submitted by EU consortium using rice bran as a basic ingredient) B- Fund for Pectin Pilot Production from orange peels -LE 1 Million, short listed for acceptance (STDF)
  22. 22. Health Tech Shared Finance For Rice bran Business; US$ 500 000 (for production and marketing. (20142016) For pectin production; US$ 500- 000 (for production (2016-2017)
  23. 23. The Investor/ company… WIN (ROI) The Customer .. WIN (affordable high Q) The Community .. WIN (make use of waste materials and both health and wealth standards are improved) Thanks Dr. Helal