Q & A for Literature search

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2008/07/19 @ 花蓮 慈濟醫院 實證醫學工作坊

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  • Q & A for Literature search

    1. 1. Q & A for Literature search 2008 July 基隆長庚.楊宗翰醫師 實證醫學中心 風濕過敏免疫科
    2. 2. Five Steps <ul><li>Ask </li></ul><ul><li>Acquire (Search) </li></ul><ul><li>Appraise </li></ul><ul><li>Apply </li></ul><ul><li>Audit </li></ul><ul><li>問 </li></ul><ul><li>查 </li></ul><ul><li>讀 </li></ul><ul><li>用 </li></ul><ul><li>審 </li></ul>
    3. 3. <ul><li>Question </li></ul><ul><li>Database selection </li></ul><ul><ul><li>What : Content > Search > Result </li></ul></ul><ul><li>Search strategy </li></ul><ul><ul><li>How : Keywords + MeSH > Hedges > Filters </li></ul></ul>
    4. 4. Q1: What is the questions? <ul><li>Type of your question? </li></ul><ul><ul><li>B or F </li></ul></ul><ul><li>Type of your foreground questions? </li></ul><ul><ul><li>Dx / Rx / Etiology / Prognosis </li></ul></ul>
    5. 5. Step 1 - Question <ul><li>那種問題? </li></ul><ul><ul><li>Foreground or Background </li></ul></ul><ul><li>那類問題? </li></ul><ul><ul><li>Frequency (incidence or prevalence) </li></ul></ul><ul><ul><li>Diagnosis </li></ul></ul><ul><ul><li>Harm (etiology or risk factors) </li></ul></ul><ul><ul><li>Prognosis (natural history) </li></ul></ul><ul><ul><li>Treatment (intervention) </li></ul></ul><ul><li>最佳解決方案(研究方法)! </li></ul>
    6. 6. Q2: Current best evidence?
    7. 7. 橫斷面研究 病例系列或由輕重不等的病患所組成的世代研究 病例系列 病例系列 IV <ul><li>回溯性世代研究 </li></ul><ul><li>病例對照研究 </li></ul><ul><li>隨機對照試驗的 未治療對照組 </li></ul><ul><li>回溯性世代研究 </li></ul><ul><li>非連續取樣 的橫斷面研究 </li></ul><ul><li>診斷型病例對照研究 </li></ul><ul><li>非隨機 的對照 試驗型 研究 </li></ul><ul><li>觀察型研究 ,但需有同時進行中的對照組,如: 世代研究 或 病例對照研究 </li></ul>III 前瞻性 世代研究 前瞻性起始 世代研究 由連續或隨機取樣組成的 橫斷面研究 隨機對照 試驗 II 第 II 級 證據的 系統回顧 (systematic review) I 病因 預後 診斷 治療 等級
    8. 8. Q3: Type of evidences <ul><li>Original articles </li></ul><ul><li>EBM reviews </li></ul><ul><ul><li>Article review </li></ul></ul><ul><ul><li>Article review based on cases (critical appraisal topics, CATs) </li></ul></ul><ul><ul><li>Topic review </li></ul></ul><ul><li>Narrative reviews </li></ul>
    9. 9. <ul><li>Question </li></ul><ul><li>Database selection </li></ul><ul><ul><li>What : Content > Search > Result </li></ul></ul><ul><li>Search strategy </li></ul><ul><ul><li>How : Keywords + MeSH > Hedges > Filters </li></ul></ul>
    10. 10. Q4: Which database?
    11. 11. Q5: Differences between DBs <ul><li>Content </li></ul><ul><li>Search </li></ul><ul><li>Result </li></ul>
    12. 12. Q6: Database – content (5S)
    13. 13. Q7: Database – content (3) <ul><li>Type of Content </li></ul><ul><ul><li>Original </li></ul></ul><ul><ul><li>Review </li></ul></ul><ul><ul><ul><li>EBM review (topic or article) </li></ul></ul></ul><ul><ul><ul><li>narrative review </li></ul></ul></ul><ul><li>Primary or Secondary </li></ul>
    14. 14. Q8: how we search? <ul><li>Keywords </li></ul><ul><ul><li>truncation ($/*; Salmonell* or child$) </li></ul></ul><ul><ul><li>Related Terms </li></ul></ul><ul><li>indexed terms </li></ul><ul><ul><li>MeSH (Medline/Pubmed) </li></ul></ul><ul><ul><li>CINAHL Index Terms (CINAHL) </li></ul></ul><ul><ul><li>EMTAGs (EMBASE) </li></ul></ul><ul><li>automatic term mapping (ATM) </li></ul>
    15. 15. Q9: What is MeSH/index terms <ul><li>同義辭典 </li></ul>
    16. 16. Q10: more about MeSH <ul><li>Tree / Hierarchy </li></ul><ul><ul><li>Explode / Not Explode </li></ul></ul><ul><li>Major Topic / not Major Topic </li></ul><ul><ul><li>Focus / Not Focus </li></ul></ul>
    17. 17. Q11: Is the more the better? <ul><li>Quality --- Quantity </li></ul>
    18. 18. Q12: how the results order? <ul><li>Relevance </li></ul><ul><ul><li>Definition of relevance </li></ul></ul><ul><li>Publication year </li></ul><ul><li>Search refinement </li></ul><ul><ul><li>sub-population </li></ul></ul><ul><ul><li>category (Dx, Rx, Prognosis, Etiology) </li></ul></ul>
    19. 19. Q13: Medline & Medline-clone <ul><li>PubMed (Medline + 2% extra) </li></ul><ul><ul><li>Mechanism of ATM </li></ul></ul><ul><li>Medline </li></ul><ul><li>Other Medline brothers & sisters … </li></ul>
    20. 20. Q14: OVID families <ul><li>Medline @ OVID Journals @ OVID Books @ OVID [email_address] </li></ul><ul><li>Should we use All EBMR? </li></ul><ul><ul><li>Cochrane Systematic Review </li></ul></ul><ul><ul><li>DARE (Synoposis) </li></ul></ul><ul><ul><li>Cochrane Trial Register </li></ul></ul>
    21. 21. Q15: MD Consults
    22. 22. Q16: Cochrane Library <ul><li>Cochrane Database of Systematic Reviews (CDSR; Cochrane Reviews) </li></ul><ul><li>Database of Abstracts of Reviews of Effects (DARE; Other Reviews) </li></ul><ul><li>Cochrane Central Register of Controlled Trials (CENTRAL; Clinical Trials) </li></ul><ul><li>Cochrane Methodology Register (CMR; Methods Studies) </li></ul><ul><li>Health Technology Assessment Database (HTA; Technology Assessments) </li></ul><ul><li>NHS Economic Evaluation Database (NHSEED; Economic Evaluations) </li></ul>
    23. 23. Q16: other secondary sources <ul><li>What, Why, & what we should know before searching? </li></ul><ul><ul><li>EBM topic reviews (summaries) </li></ul></ul><ul><ul><li>EBM article reviews based on Case (Critical Appraisal Topics, CATs) </li></ul></ul><ul><ul><li>EBM article reviews (synopses) </li></ul></ul><ul><ul><li>EBM synthesis (systematic review) </li></ul></ul><ul><ul><li>Guidelines </li></ul></ul>
    24. 24. Appraise <ul><li>Appraised by yourself … </li></ul><ul><ul><li>Time consuming </li></ul></ul><ul><ul><li>Original articles </li></ul></ul><ul><li>Appraised by authorized specialists </li></ul><ul><ul><li>Systems, Synopses, Synthesis </li></ul></ul><ul><ul><li>Review articles (narrative, systematic, EBM review) </li></ul></ul><ul><ul><ul><li>topic or article review </li></ul></ul></ul>Dave Sackett
    25. 25. Step 2 – Select Database <ul><li>Which & Why? </li></ul><ul><ul><li>Contents </li></ul></ul><ul><ul><li>How to search? </li></ul></ul><ul><ul><li>Results of search? </li></ul></ul>
    26. 26. <ul><li>Question </li></ul><ul><li>Database selection </li></ul><ul><ul><li>What : Content > Search > Result </li></ul></ul><ul><li>Search strategy </li></ul><ul><ul><li>How : Keywords + MeSH > Hedges > Filters </li></ul></ul>
    27. 27. Prepare for search <ul><li>Keywords + MeSH </li></ul><ul><li>Hedges / Strategy </li></ul><ul><li>Filters </li></ul>
    28. 28. Q17: Best keywords / MeSH? <ul><li>Based on search result. </li></ul>
    29. 29. Q17: Best keywords / MeSH? <ul><li>Based on search result. </li></ul>
    30. 30. Q19: Abbreviation ok? <ul><li>No. </li></ul>
    31. 31. <ul><li>決定 Keywords </li></ul><ul><ul><li>縮寫 </li></ul></ul><ul><ul><ul><li>AMI, BPH, CAP , CAD </li></ul></ul></ul><ul><ul><ul><li>DM , IDA , MM , SLE </li></ul></ul></ul><ul><ul><li>中文 > 英文 </li></ul></ul><ul><ul><ul><li>漢英字典(非醫學 & 醫學) </li></ul></ul></ul><ul><ul><li>Results from searches </li></ul></ul><ul><ul><ul><li>Medline, Google, … </li></ul></ul></ul>Step 3.1 - Keywords
    32. 32. Step 3.2 - Hedges <ul><li>1 concept or keyword a line (an entry) </li></ul><ul><li>P & I more important, use C & O to narrow down results </li></ul><ul><li>OR & AND </li></ul><ul><li>NEAR, ADJ … </li></ul><ul><li>! NOT </li></ul>
    33. 33. Q20: few results <ul><li>Check the spelling of your keywords </li></ul><ul><ul><li>Don’t use abbreviations. </li></ul></ul><ul><li>Use the more common words in your first result. </li></ul><ul><li>Fewer combination. </li></ul>
    34. 34. Q21: many results <ul><li>Refine </li></ul><ul><li>Filters </li></ul>
    35. 35. Type of filters <ul><li>最佳解決方案 </li></ul><ul><li>Quality filters & Limit </li></ul><ul><ul><li>clinical query </li></ul></ul><ul><ul><li>methodology (publication type) filters </li></ul></ul><ul><ul><li>x English, full text, review </li></ul></ul>
    36. 36. Q22: Best DBs for different Q?
    37. 37. Q23: Best strategie for different Q?
    38. 38. Summary
    39. 39. Acquire / 查 <ul><li>Question </li></ul><ul><li>Database selection </li></ul><ul><ul><li>What </li></ul></ul><ul><ul><li>Content > Search > Result </li></ul></ul><ul><li>Search strategy </li></ul><ul><ul><li>How </li></ul></ul><ul><ul><li>Keywords + MeSH > Hedges > Filters </li></ul></ul>
    40. 40. Current Best Evidence
    41. 43. Databases <ul><li>Background questions </li></ul><ul><ul><li>Reviews </li></ul></ul><ul><ul><ul><li>Uptodate, MD Consult (Textbooks, Clinics) </li></ul></ul></ul><ul><ul><ul><li>Ovid (Books@Ovid, Journals@Ovid) </li></ul></ul></ul><ul><li>Foreground questions </li></ul><ul><ul><li>First Consult, Clin-eguide (Ovid), ACP PIER, Dynamed, InfoPOEMs </li></ul></ul><ul><ul><li>Guidelines, or EBM-style review or CATs, Bandolier </li></ul></ul><ul><ul><li>Hand searches PubMed (clinical queries, methodological filters) </li></ul></ul>

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