Ch 5: Integumentary SystemYou gotta have skin;All you really need is skin.Skins the thing, that if youve got itoutside,It ...
   Cutaneous Membrane,    i.e. skin       Epidermis       Dermis       Hypodermis   Accessory Structures       Excre...
   Type of Epithelium?   Avascular   Different layers    (= strata)       4 layers in thin skin       5 layers in thi...
A Concept Map (from Histo, Part 1                                     Epithelial                                      tiss...
Cell types:    Stem cells (basal cells)    Melanocytes    Merkel cells (touch receptors in hairless skin only) = stratu...
   Stem cell daughter cells (some can still divide)       Establishment of Desmosomes           The desmosomes create t...
   Cells displaced from stratum spinosum  Keratinocytes      Production of keratohyalin and keratin fibers      Cells ...
    In “thick skin” only, i.e., palms of hands and soles of feet    Cells do not stain well  clear (lucid) looking    M...
   Many layers of flattened, dead cells, filled with keratin   Continually sloughed   Water-resistant but not water pro...
Refers to epidermis   Average 0.08 mm          Up to 1.5 mm   Most of body             Where??
c
Depends on 3 pigments:     Hemoglobin (dermal blood supply)         Reddish tones         Pale, due to?         Bluish...
Function ? UV protection?Number ofmelanocytes samein all people,production levelsdiffer !
Albinism           Vitiligo
1. Papillary layer   Areolar (loose)   c.t.2. Reticular layer   dense irregular   c.t.
Review of Connective Tissue•Loose (areolar)   •Irregular          •Hyaline    •Compact      •Reticular   •Regular         ...
   Dermal papillae         project between         epidermal ridges.     Consist of        Loose c.t.M      Capillarie...
Consist of   Dense irregular c.t.   Accessory    Structures       Hair       Glands       Nerves       Blood Supply
   2 other names       Subcutaneous Layer        (subcutis)       Superficial fascia   Indistinct boundary (c.t.    fi...
   Hair follicles and hair   Glands       1. Sebaceous Glands       2. Apocrine glands       3. Eccrine sweat glands...
   5 million    hairs/human body.    (98% not on top of    head)   Three hair types    (vellus – intermediate –    termi...
Skin Glands
Sebum discharged mostly into hair   follicles   (lubrication & bactericidal)                                  Sebaceous fo...
   Empty into hair follicle   Location: armpits, groin, nipples   Viscous, cloudy secretion  good nutrient source for ...
   Merocrine secretion   Empty directly onto skin surface   Location: most all over body (esp.    abundant on palms & s...
Other integumentary Glands:   Mammary glands: Modified apocrine    sweat glands   Ceruminous glands: Modified sweat    g...
1. Basal Cell Carcinoma (Epithelioma)   BCC    1. Most common, not malignant 2. Squamous Cell CA    1. Stratum spinosum 3....
Skin and Aging Process
Chapter5 integumentarymarieb
Chapter5 integumentarymarieb
Chapter5 integumentarymarieb
Chapter5 integumentarymarieb
Chapter5 integumentarymarieb
Chapter5 integumentarymarieb
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Chapter5 integumentarymarieb

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Chapter5 integumentarymarieb

  1. 1. Ch 5: Integumentary SystemYou gotta have skin;All you really need is skin.Skins the thing, that if youve got itoutside,It helps keep your insides in. Alan Sherman (1924-1973) Developed by John Gallagher, MS, DVM
  2. 2.  Cutaneous Membrane, i.e. skin  Epidermis  Dermis  Hypodermis Accessory Structures  Excretory glands (?)  Hair  Nails
  3. 3.  Type of Epithelium? Avascular Different layers (= strata)  4 layers in thin skin  5 layers in thick skin
  4. 4. A Concept Map (from Histo, Part 1 Epithelial tissues Squamous Columnar CuboidalSimple Stratified Simple Simple Keratinized Pseudostratified Stratified Nonkeratinized Transitional
  5. 5. Cell types:  Stem cells (basal cells)  Melanocytes  Merkel cells (touch receptors in hairless skin only) = stratum Stratum basale germinativumInnermost,single layer
  6. 6.  Stem cell daughter cells (some can still divide)  Establishment of Desmosomes  The desmosomes create the “spines” as artifact pulls the cells apartSeveral cellsthick
  7. 7.  Cells displaced from stratum spinosum  Keratinocytes  Production of keratohyalin and keratin fibers  Cells start to die. Dehydration leaves interlocked layers of keratin and keratohyalinSmall Stratumgranules of granulosumkeratin
  8. 8.  In “thick skin” only, i.e., palms of hands and soles of feet Cells do not stain well  clear (lucid) looking Mostly Stratum keratin lucidum
  9. 9.  Many layers of flattened, dead cells, filled with keratin Continually sloughed Water-resistant but not water proof ( insensible perspiration) Relatively dry - advantage? Keratinization occurs everywhere except for anterior surface of eye 15-30 layers (much thicker in thick skin)
  10. 10. Refers to epidermis Average 0.08 mm  Up to 1.5 mm Most of body  Where??
  11. 11. c
  12. 12. Depends on 3 pigments:  Hemoglobin (dermal blood supply)  Reddish tones  Pale, due to?  Bluish (=?), due to?  Melanin  Produced by melanocytes of stratum basale  Carotene  Obtained from plant foods
  13. 13. Function ? UV protection?Number ofmelanocytes samein all people,production levelsdiffer !
  14. 14. Albinism Vitiligo
  15. 15. 1. Papillary layer Areolar (loose) c.t.2. Reticular layer dense irregular c.t.
  16. 16. Review of Connective Tissue•Loose (areolar) •Irregular •Hyaline •Compact •Reticular •Regular •Elastic •Spongy •Adipose •Elastic •Fibrocartilage This is similar to Table 4.2
  17. 17.  Dermal papillae project between epidermal ridges. Consist of  Loose c.t.M  Capillaries  Tactile receptors
  18. 18. Consist of Dense irregular c.t. Accessory Structures  Hair  Glands  Nerves  Blood Supply
  19. 19.  2 other names  Subcutaneous Layer (subcutis)  Superficial fascia Indistinct boundary (c.t. fibers interwoven)  Loose c.t.Function  Stabilization of skin while allowing for independent movement
  20. 20.  Hair follicles and hair Glands  1. Sebaceous Glands  2. Apocrine glands  3. Eccrine sweat glands Nails
  21. 21.  5 million hairs/human body. (98% not on top of head) Three hair types (vellus – intermediate – terminal) Function ? Hair color Growth cycle
  22. 22. Skin Glands
  23. 23. Sebum discharged mostly into hair follicles (lubrication & bactericidal) Sebaceous follicles, = Large sebaceous glands, discharge directly to epidermis Folliculitis; furuncle (boil); acne
  24. 24.  Empty into hair follicle Location: armpits, groin, nipples Viscous, cloudy secretion  good nutrient source for bacteria (odor !!) Secretion may contain Pheromones Secretion begins at puberty and is stimulated during emotional distress (cold sweat)
  25. 25.  Merocrine secretion Empty directly onto skin surface Location: most all over body (esp. abundant on palms & soles: ~ 500/cm2) Clear, watery secretion (99% H2O; rest NaCl + some waste products) Sensible perspiration; Function: ?
  26. 26. Other integumentary Glands: Mammary glands: Modified apocrine sweat glands Ceruminous glands: Modified sweat glands in ears
  27. 27. 1. Basal Cell Carcinoma (Epithelioma) BCC 1. Most common, not malignant 2. Squamous Cell CA 1. Stratum spinosum 3. Melanoma SCCIris Melanoma Dermal Melanoma
  28. 28. Skin and Aging Process

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