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BioKnowledgy DP 2.1 Molecules to metabolism- bottom line

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BioKnowledgy DP 2.1 Molecules to metabolism- bottom line

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BioKnowledgy DP 2.1 Molecules to metabolism- bottom line

  1. 1. 2 Molecular biology – 2.1 Molecules to metabolism Name: http://www.bioknowledgy.info/ (Chris Paine) 2.1 Molecules to metabolism - the bottom line The learning Statements The can you statements tell you what you notes should enable you to do. They are guidance to a minimum expectation. The deeper your understanding the easier you will find it to respond to questions and communicate your understanding. 2.1.U1 Molecular biology explains living processes in terms of the chemical substances involved. Can you define molecular biology? Can you compare and contrast the reductionist and systems approach to molecular biology? 2.1.U2 Carbon atoms can form four covalent bonds allowing a diversity of stable compounds to exist. Can you state the number and type of bond carbon can form with other atoms? Can you explain why these two properties allow such a large diversity of molecules to be formed? 2.1.U3 Life is based on carbon compounds including carbohydrates, lipids proteins and nucleic acids. Can you list the four major groups of carbon compounds used by organisms? Can you for each group state the elements contained, outline the basic properties and give examples 2.1.S2 Identification of biochemicals such as sugars, lipids, or amino acids from molecular diagrams. Can you state the generalised formula of sugars and know that the monomers exist as ring shaped molecules Can you state the generalised formula of fatty acids and know that three acids can be joined by a glycerol to form a triglyceride Can you know the generalised amino acid structure (including the amine, acid and r-group)? Can you deduce the type of biochemical molecule shown in a diagram using your understanding from the prior points? 2.1.S1 Drawing molecular diagrams of glucose, ribose, a saturated fatty acid and a generalized amino acid. Can you draw a molecular diagram of ribose? Can you draw a molecular diagram of glucose (alpha or beta)? Can you draw a molecular diagram of a saturated fatty acid (identify the carboxyl/acid group)? Can you draw the generalised structure of an amino acid (Label the amine group, carboxyl group, and R group)? 2.1.U4 Metabolism is the web of all the enzyme-catalysed reactions in a cell or organism. Can you define metabolism and catalysis? Can you state the role of enzymes in metabolism? 2.1.U5 Anabolism is the synthesis of complex molecules from simpler molecules including the formation of macromolecules from monomers by condensation reactions. Can you Define anabolism, monomer, polymer and synthase Can you Describe condensation reactions, giving two examples. Can you draw a diagram of a condensation reaction using simple shapes to represent monomers? Can you give two examples of anabolism? 2.1.U6 Catabolism is the breakdown of complex molecules into simpler molecules including the hydrolysis of macromolecules into monomers. Can you Define catabolism and hydrolase. Can you Contrast anabolism and catabolism. Can you Describe hydrolysis reactions, giving two examples.
  2. 2. http://www.bioknowledgy.info/ (Chris Paine) Can you draw a diagram of a hydrolysis reaction using simple shapes to represent monomers? 2.1.A1 Urea as an example of a compound that is produced by living organisms but can also be artificially synthesized. Can you state that urea is a metabolic waste molecule normally produced by deamination of amino acids. Can you state that it is possible to artificially synthesise urea. Nature of science: Falsification of theories - the artificial synthesis of urea helped to falsify Vitalism. Can you define Vitalism? Can you explain how some regard the artificial synthesis of urea as a falsification of Vitalism? Recommended resources http://www.bioknowledgy.info/21-molecules-to-metabolism.html Allott, Andrew. Biology: Course Companion. S.l.: Oxford UP, 2014. Print.

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