Diuretics

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Diuretics

  1. 1. Drugs Affecting Urinary System Diuretics
  2. 2. Outlines: 1- Diuretics A-Loop Diuretics → Furesmide (Lasix®) B- Thiazides → Chlorothiazide (Diuril®) C- Potassium Sparing Diuretics → Spironolactone (Aldactone®) D- Osmotic Diuretics → Mannitol (Osmitrol®) C- Carbonic Anhydrase Inhibitors → Acetazolamide (Diamox®) 2- Urinary antiseptics - Ciprofluxacine HCl (Cipro®) - Nitrofurantoin (Macrodantin®) 3- Urinary analgesic Phenazopyredine
  3. 3. References: • Catherine Paradiso.1998 , Pharmacology. Lippincott’s. USA. • Bruce D. Clayton., Yvonne N. Stock.1997, Basic pharmacology for nurses. 11th Ed, Mosby.USA. • Ben Greenstein., 2004 , Trounce’s Clinical Pharmacology for Nurses. 17th Ed, Churchill Livingstone.USA. • Brunner & Suddarth., 2004 , Medical-Surgical Nursing. 10th Ed, Lippincott’s. USA. • http://en.wikipedia.org/wiki/Adenosine • Amy M. Karch., 2003 , Nursing Drug Guide. Lippincott’s. USA.
  4. 4. Diuretics Cortex Medulla Loop of Henle Thiazides Inhibit active exchange of Cl-Na in the cortical diluting segment of the ascending loop of Henle K-sparing Inhibit reabsorption of Na in the distal convoluted and collecting tubule Loop diuretics Inhibit exchange of Cl-Na-K in the thick segment of the ascending loop of Henle Collecting tubule
  5. 5. Study Questions 1. Which of the following Diuretics is the first line used to Glaucoma? a. Lasix® b. Aldactone ® c. Diuril® d. Diamox®
  6. 6. 2. Which of the following Diuretics is the first line used to Hypertension with Hyperkalemia ? a. Lasix® b. Osmitrol® c. Aldactone® d. Diamox®
  7. 7. 3. Which of the following Diuretics is the first line used in cases of Hyperaldosteronism ? a. Lasix® b. Aldactone ® c. Diuril® d. Diamox®
  8. 8. 4. Which of the following Diuretics is the first line used to Hypertention? a. Lasix® b. Aldactone® c. Diuril® d. Diamox®
  9. 9. 5. Which of the following Diuretics is the first line used in cases of edema ? a. Lasix® b. Aldactone® c. Diuril® d. Diamox®
  10. 10. 6. Which of the following Diuretics is the Second line used to Hypertension? a. Lasix® b. Aldactone® c. Diuril® d. Diamox®
  11. 11. 2. Complete the following Table with an appropriate diuretics below -Loop Diuretic -Osmotic Diuretics -Potassium Sparing diuretics -Thiazides -Carbonic Anhydrase Inhibitors Diuretic Site of Action Loop of Henle Distal Convoluted Tubule Collecting Tubule Proximal Convoluted tubule Entire Tubule Abdulqadir Nashwan

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