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AAAS talk: Bioinformatics for Biologists

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Our bioinformatics course at Austin Community College is designed for biotechnology and life sciences students who will be using bioinformatics in the workplace.

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AAAS talk: Bioinformatics for Biologists

  1. 1. Bioinformatics for Biologists www.Digital-World-Biology.com Sandra Porter Digital World Biology [email_address] Bio-Link www.bio-link.org
  2. 2. Bioinformatics = databases & software for working with biological information <ul><li>Acquire </li></ul>www.Digital-World-Biology.com Analyze Visualize Store
  3. 3. www.Digital-World-Biology.com
  4. 4. www.Digital-World-Biology.com Who are most programs designed to serve?
  5. 5. www.Digital-World-Biology.com Who uses bioinformatics?
  6. 6. Biology is an information-rich science
  7. 7. www.Digital-World-Biology.com Bioinformatics in industry Did you hear about that paper? Instrument Run Search PubMed download paper Go to GenBank download sequences Align sequences with company data Try to clone gene Design PCR primers Sequence cloned gene Make constructs for expression, sequence constructs Use microarrays / transcriptome sequencing to look at effects of construct & ligand look at structures, ligand binding
  8. 8. General <ul><li>Find information - in databases (>1300) </li></ul><ul><li>Analyze data </li></ul><ul><li>Prepare and interpret graphs </li></ul><ul><li>Use multiple kinds of software </li></ul><ul><li>Work with databases </li></ul><ul><li>Need practical skills for working with computers and the internet </li></ul>www.Digital-World-Biology.com
  9. 9. www.Digital-World-Biology.com
  10. 10. www.Digital-World-Biology.com Begin with molecular structures
  11. 11. Investigating Influenza: How might antigenic drift affect immunity? Ab Hemagglutinin Which residues contact the Ab?
  12. 12. Genetic variation & pharmacogenomics www.Digital-World-Biology.com
  13. 13. www.Digital-World-Biology.com
  14. 14. Our course at ACC www.Digital-World-Biology.com Structures Sequences Variation Gene expression

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