In today’s vibrant environment of the modern society, developers of process-aware information systems need novel methods for modeling business processes. These methods should have capabilities that could address challenges such as improved reusability of the existing process designs, reduced time-to-market, or run-time business logic change. Recognizing these challenges, the topics of variability and configurability of business process have recently received significant research attention. Although there have been many promising proposals, some important challenges still remained to be address: i) there is no clear consensus on the two key notions – variability and configurability – and their implications on business process affairs such as flexibility, dynamicity, or agility; and ii) (software) development method that can consider different aspects of variability and configurability at different stages of the development lifecycle. In this talk, we will attempt to position variability and configurability of business processes in terms of the well-adopted terminology used in (software) quality engineering. We will then make a distinction between design and run-time variability, and then explain needs for managing both types of variability, so that configurability of business process can systematically be supported. During the talk, we will reflect on the experience in the work on a rule-enhanced business process modeling language (rBPMN) and families of business processes developed by borrowing from software product lines. The talk will be finished by discussing open research challenges among which cross-community and empirical research are emphasized.