Lancefield 2011 poster Virtual Tour

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Virtual Tour of Poster presented at Lancefield 2011.

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Lancefield 2011 poster Virtual Tour

  1. 1. Bioluminescent Imaging of Streptococcus pyogenes in nasopharyngeal infection<br />Faraz Alam1, Colin Bateman1, Claire Turner1, Ken Smith2, Siouxsie Wiles1,3 & Shiranee Sriskandan1<br />1 Dept. of Infectious Diseases & Immunity, Imperial College London, London W12 0NN, UK. 2Dept. of Pathology & Infectious Diseases, Royal Veterinary College, Hertfordshire AL9 7TA , UK. <br />3 Dept. of Molecular Medicine & Pathology, University of Auckland, 1142, New Zealand.<br />The Virtual Tour<br />
  2. 2. Current Models<br />Live Mouse<br />
  3. 3. Current Models<br />Cull<br />Organs<br />Live Mouse<br />
  4. 4. Current Models<br />Cull<br />Plate<br />Organs<br />Bacteria<br />Live Mouse<br />
  5. 5. Current Models<br />Cull<br />Plate<br />Organs<br />Bacteria<br />Live Mouse<br />
  6. 6. Current Models<br />Cull<br />Plate<br />Organs<br />Bacteria<br />Live Mouse<br />Single Time Point<br />Bacteria / gram of tissue<br />Time<br />
  7. 7. Direct Culture <br />
  8. 8. Direct Culture <br />
  9. 9. Infection Longevity <br />
  10. 10. Inflammation in the Nasopharynx<br />
  11. 11. Inflammation in the Nasopharynx<br />
  12. 12. Impact of covRS on carriage<br />Turner & Sriskandan, 2007<br />
  13. 13. Impact of covRS on carriage<br />
  14. 14. Airborne Transmission<br />
  15. 15. Airborne Transmission<br />
  16. 16. Airborne Transmission<br />
  17. 17. Bioluminescence Imaging<br />Photorhabdusluminescens<br />
  18. 18. Bioluminescence Imaging<br />Camera<br />Light<br />
  19. 19. Bioluminescence Imaging<br />Camera<br />Light<br />
  20. 20. Bioluminescence Imaging<br />Camera<br />Light<br />
  21. 21. Growth Kinetics<br />
  22. 22. Growth Kinetics<br />
  23. 23. In vivo Growth Kinetics<br />
  24. 24. In vivo Growth Kinetics<br />
  25. 25. In vivo Growth Kinetics<br />
  26. 26. In vivo Growth Kinetics<br />
  27. 27. In vivo Growth Kinetics<br />
  28. 28. Bioluminescence in the nasopharynx<br />
  29. 29. Longitudinal imaging<br />
  30. 30. Longitudinal imaging<br />
  31. 31. Vaccination Study<br />Day 1<br />Day 14<br />Day 28<br />Day 35<br />PBS Vaccinated<br />Heat Killed Bacteria<br />
  32. 32. Vaccination Study<br />Day 2<br />Day 3<br />Day 4<br />Day 1<br />PBS Vaccinated<br />Heat Killed Bacteria<br />
  33. 33. Vaccination Study<br />
  34. 34. Mucosal Transmission<br />
  35. 35. Summary<br />
  36. 36. Summary<br />
  37. 37. Summary<br />Photograph/ Nasal Sample<br />Single Time Point<br />Bacteria / gram of tissue<br />Time<br />

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