Church apr2013

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Talk to high school students visiting NIH.

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  • What exactly do we mean by ‘The Human Genome’
  • This is a picture of one person’s genome
  • Church apr2013

    1. 1. Human Genomes
    2. 2. The Human Genome Project
    3. 3. Figure 1. Identification of recombination events.Chowdhury R, Bois PRJ, Feingold E, Sherman SL, et al. (2009) Genetic Analysis of Variation in Human Meiotic Recombination. PLoS Genet 5(9):e1000648. doi:10.1371/journal.pgen.1000648http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000648
    4. 4. color colourweek weakweek wlek
    5. 5. Figure 1. Sequence Structure of Structural Variant and Genotyping Assay DesignKidd JM, Newman TL, Tuzun E, Kaul R, et al. (2007) Population Stratification of a Common APOBEC Gene Deletion Polymorphism. PLoS Genet3(4): e63. doi:10.1371/journal.pgen.0030063http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.0030063
    6. 6. ClonesClonesIHGSC, Nature 2004
    7. 7. RP11-34P13 64E8 RP4-669L17 RP5-857K21 RP11-206L10 RP11-54O7Gaps
    8. 8. http://theamazingios6maps.tumblr.com/
    9. 9. Preview of GRCh38 (scheduled Fall 2013)TEX28 TKTL1LOC101060233(opsin related)LOC101060234(TEX28 related)GRCh37 (current reference assembly)chrX
    10. 10. 23andMe
    11. 11. NOT
    12. 12. Matsunaga (1962)

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