Cardiovascular function and disorders (1)

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Cardiovascular function and disorders (1)

  1. 1. NURS 315/501 Bootcamp Lecture: Cardiovascular Function and Disorders
  2. 2. Cardiovascular Function <ul><li>Compare and contrast the pulmonary versus the systemic vascular system. </li></ul>
  3. 3. Cardiovascular Function <ul><li>Describe the determinants of blood pressure. </li></ul><ul><li>Compare and contrast the differences in diastole and systole in relation to volume, electrical activity, and heart sounds. </li></ul>
  4. 4. W I G G E R S D I A G R A M
  5. 5. Cardiovascular Function <ul><li>Define Cardiac Output ( CO). </li></ul><ul><li>Describe the Frank Starling Law mechanism to optimize preload. </li></ul><ul><li>What are the major determinants of afterload? </li></ul><ul><li>Describe the relationship between cardiac output and afterload. </li></ul><ul><li>Name and describe the determinants of contractility. </li></ul>
  6. 6. Autoregulation <ul><li>Explain the short-term regulatory influence of: </li></ul><ul><ul><li>Local tissue </li></ul></ul><ul><ul><li>ANS </li></ul></ul><ul><ul><li>Baroreceptors/chemoreceptors </li></ul></ul><ul><ul><li>Humoral mechanism </li></ul></ul><ul><ul><li>On blood pressure </li></ul></ul>
  7. 7. Hypertension <ul><li>Discuss the long term manisfestations of HTN on: </li></ul><ul><ul><li>Heart </li></ul></ul><ul><ul><li>Kidneys </li></ul></ul><ul><ul><li>Brain </li></ul></ul><ul><ul><li>Peripheral vasculature </li></ul></ul><ul><ul><li>Retina </li></ul></ul><ul><li>Describe the treatment algorithm for HTN. </li></ul>
  8. 8. Orthostatic Hypotension <ul><li>Explain the physiological mechanism for orthostatic hypotension. </li></ul>
  9. 9. Pharmacotherapy for HTN <ul><li>Diuretics </li></ul><ul><ul><li>Draw a nephron </li></ul></ul><ul><ul><li>Describe the sites of action of the different types of diuretics </li></ul></ul><ul><ul><li>Describe their MOA. </li></ul></ul><ul><ul><li>Name potential drug interactions with the use of diuretics. </li></ul></ul><ul><li>ACE Inhibitors </li></ul><ul><ul><li>Describe their MOA </li></ul></ul><ul><ul><li>Describe common adverse effects. </li></ul></ul><ul><ul><li>Identify potential drug interactions. </li></ul></ul>
  10. 10. Pharmacotherapy for HTN <ul><li>Angiotensin II Receptor blocker </li></ul><ul><ul><li>Describe the MOA </li></ul></ul><ul><ul><li>Describe adverse effects. </li></ul></ul><ul><ul><li>Identify potential drug interactions. </li></ul></ul><ul><li>Beta-Blockers </li></ul><ul><ul><li>Describe their MOA </li></ul></ul><ul><ul><li>Compare and contrast their effects on: </li></ul></ul><ul><ul><ul><li>Peripheral tissue </li></ul></ul></ul><ul><ul><ul><li>Heart </li></ul></ul></ul><ul><ul><ul><li>Lungs </li></ul></ul></ul>
  11. 11. Pharmacotherapy for HTN <ul><li>Calcium Channel Blockers </li></ul><ul><ul><li>Describe their MOA </li></ul></ul><ul><ul><li>Identify potential drug interactions. </li></ul></ul><ul><ul><li>Discuss relevant patient teaching points. </li></ul></ul><ul><li>Alpha-1 Antagonists </li></ul><ul><ul><li>Describe their MOA </li></ul></ul><ul><ul><li>Compare and contrast their effects on: </li></ul></ul><ul><ul><ul><li>Peripheral tissue </li></ul></ul></ul><ul><ul><ul><li>Heart </li></ul></ul></ul><ul><ul><ul><li>Lungs </li></ul></ul></ul><ul><ul><li>Describe common adverse effects. </li></ul></ul>
  12. 12. Pharmacotherapy for HTN <ul><li>Centrally Acting Alpha-2 Agonists </li></ul><ul><ul><li>Describe their MOA </li></ul></ul><ul><ul><li>Identify alternative pharmacotherapeutic uses. </li></ul></ul><ul><ul><li>Name common adverse effects </li></ul></ul><ul><ul><li>Discuss relevant patient teaching points. </li></ul></ul>
  13. 13. Pharmacotherapy for HTN <ul><li>Name 3 direct acting vasodilators. </li></ul><ul><li>What conditions are they used for? </li></ul><ul><li>What characterizes HTN emergency </li></ul>
  14. 14. Disorders of Arterial Circulation <ul><li>Describe the metabolism of lipoproteins: </li></ul><ul><ul><li>VLDL </li></ul></ul><ul><ul><li>LDL </li></ul></ul><ul><ul><li>HDL </li></ul></ul><ul><li>Identify the different types of anti-hyperlipidemic agents. </li></ul>
  15. 15. Disorders of Arterial Circulation <ul><li>Describe the MOA, common adverse effects, and potential drug interactions for the following: </li></ul><ul><ul><li>Statins </li></ul></ul><ul><ul><li>Fibric acid derivatives </li></ul></ul><ul><ul><li>Ezetimibe (Zetia) </li></ul></ul><ul><ul><li>Nicotinic acids </li></ul></ul><ul><ul><li>Bile acid sequestrants </li></ul></ul>

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