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Pharma master class v5

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Presentation to DayOne accelerator on the opportunity and challenges of working with Big Pharma by Frank Kumli, BaselArea.swiss and DayOne

Published in: Health & Medicine
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Pharma master class v5

  1. 1. 1 An initiative managed by BaselArea.swiss in close collaboration with the Canton of Basel-Stadt Pharma Masterclass: The Digital Health opportunity at Big Pharma
  2. 2. It is time to wake up …also in Healthcare! 2
  3. 3. Agenda 3 Trends2 The opportunity3 Big Pharma1 Working with Big Pharma4
  4. 4. Big Pharma
  5. 5. Top 10 Pharma and global Pharma spending 5
  6. 6. Top 10 Leading Therapeutic Areas 6
  7. 7. Drug Development Process 7 https://spharm-inc.com/the-drug-review-and-approval-process-in-canada-an-eguide/
  8. 8. Pharma Cash flows 8
  9. 9. Trends
  10. 10. The health services landscape is in the midst of a massive shift 1 0 https://assets.ey.com/content/dam/ey-sites/ey-com/en_gl/topics/digital/ey-when-the-human-body-is-the-biggest-data- platform-who-will-capture-value.pdf
  11. 11. Pharma: a broken Business Model An industry that needs to reinvent itself 1 1 Source: https://www.technology<eview.com/s/609647/google-has-released-an-ai-tool-that-makes-sense-of-your-genome/©
  12. 12. Pharma sales reps Changing business model for Pharma 1 2 https://www.scoop.it/topic/pharmaguy-s-take-on-drug-industry-news/p/4041114978/2015/04/10/pharma-sales-reps-declined-denied
  13. 13. It is time to wake up …also in Healthcare! 13
  14. 14. Why? The Healthcare reality: Complexity Wasteful and not patient centric 1 4 Source: http://www.icosystem.com/simplifying-the-complexity-of-healthcare/
  15. 15. Why? The Healthcare opportunity: Efficiency Probably the biggest business opportunity around 1 5 Source: https://www-01.ibm.com/common/ssi/cgi-bin/ssialias?htmlfid=HLW03016USEN
  16. 16. Non traditional player 1: Tech Data, data, data…and trust 16 https://www.bloomberg.com/news/articles/2018-11-01/apple-watch-heart-study-with-stanford-signs-up-400-000-people/
  17. 17. Non traditional player 2: Platforms GAFA and BATX 17 https://www.mddionline.com/amazon%E2%80%99s-latest-move-medtech-big-deal https://www.pymnts.com/amazon-commerce/2017/amazon-prepares-to-sell-online-pharmaceuticals
  18. 18. Non traditional player 3: Retail In your community, outside of expensive care settings 18 Source: https://www.japantimes.co.jp/news/2017/03/06/business/lawson-offers-specialized-services-elderly-customers/#.Wk8wPLaZP-Z
  19. 19. Non traditional player 4: Insurance Pay-as-you live! https://www.digfingroup.com/muang-thai/ https://www.digfingroup.com/muang-thai/ https://www.scmp.com/tech/enterprises/article/2173657/ping-good-doctor-blazes-trail-developing-unstaffed-ai-assisted/
  20. 20. Non traditional player 5: THE PATIENT! Needs to be be at the center 20 Source: Source: https://www.pymnts.com/amazon-commerce/2017/amazon-prepares-to-sell-online-pharmaceuticals
  21. 21. Industry Convergence! Across all industries – Healthcare is next 21 https://www.weforum.org/agenda/2018/11/how-the-biological-century-will-transform-healthcare/
  22. 22. New tech and cost constraints shift power away from life sciences https://assets.ey.com/content/dam/ey-sites/ey-com/en_gl/topics/digital/ey-when-the-human-body-is-the-biggest-data- platform-who-will-capture-value.pdf
  23. 23. Impact on Big Pharma
  24. 24. What’s at stake? A unique desity of life sciences companies 2 4
  25. 25. What’s at stake for the region? A unique density of life sciences companies 2 5
  26. 26. What’s at stake? The Basel Region has a long standing tradition in reinventing itself! 2 6
  27. 27. What’s at stake? Taking the next step forward 2 7
  28. 28. Industry transformation in Basel An acceleration of business transformation! 2 8 https://www.bloomberg.com/news/articles/2018-10-09/sneaking-into-patients-pockets-one-medical-app-at-a-time/ https://www.mobihealthnews.com/content/pear-therapeutics-novartis-announce-commercial-launch-reset
  29. 29. Life Sciences 4.0: From blockbuster products to data-driven platforms 2 9 https://assets.ey.com/content/dam/ey-sites/ey-com/en_gl/topics/digital/ey-when-the-human-body-is-the-biggest-data- platform-who-will-capture-value.pdf
  30. 30. Business Models https://consulting.ey.com/better-with-age-the-silver-opportunity/
  31. 31. The opportunity
  32. 32. Pain points across the Pharma value chain 3 2 Research ► Costs ► Patient recruitment, retention maintenance and efficiency ► RWE requirements ► Patient data management Manufacturing ► Efficiency ► Agility ► Smaller, personalized batches ► Gene therapy manufacturing Supply Chain ► Forecasting and planning ► Medical supply tracking ► Counterfeit avoidance ► Cold chain M&S Access ► Changing Physician, Payor and Patient behaviour ► Digitalization ► Regulatory requirements ► Demonstratio n of value (RWE) ► Risk sharing agreements ► Unhealthy lifestyles ► Pressure for pharma to engage beyond treatment ► Lack of awareness ► Poor patient data management ► Treatment complexity ► Poor care transition ► Late diagnosis • Complex diagnosis ► treatment ► Lack of awareness Patient Experience Prevention Diagnosis Follow-upTreatment ► Remote care ► Discharge management ► Health care management solutions ► Personalized health management ► Lack of adherence (Concordance + compliance) ► Treatment complexity Healthcare Systems - Hospitals ► Cost ► Productivity ► Translationa- bility ► Rigidity of research organizations Development
  33. 33. Examples of Digital disruption is occurring across the value chain 3 3 Research ► Virtual trials / centralized monitoring ► Enrolment prediction; Recruitment platforms ► Real-world data collection and analysis ► Digital biomarkers ► Robotic Process Optimization Manufacturing ► Automation ► Preventive maintenance ► Simulation ► Continuous manufacturing ► 3D printing ► Gene and personalized drugs manufacturing Supply Chain ► Digital supply chain management ► Inventory and asset management enabled by connected software ► Autonomous mobile robot enabled supply management ► Medical supply tracking M&S Access ► Digital supply chain management ► Supply chain simulation ► Inventory and asset management enabled by connected software ► Automation, Autonomous mobile robot enabled supply management ► Patient engagement ► Behavioural change ► Consumer genomics ► Digiceuticals ► Electronic health and medical records ► Clinical Decision Support ► Patient and physician engagement solutions ► Lean, agile trainings ► New approaches to (companion) diagnostics ► Clinical Decision Support ► Consumer diagnostics Patient Experience Prevention Diagnosis Follow-upTreatment ► Remote care ► Discharge management ► Health care management solutions ► Personalized health management ► Clinical Decision Support ► Beyond the pill solutions ► Treatment management solutions Healthcare Systems - Hospitals ► Predictive modelling ► R&C controlling Development
  34. 34. Working with big Pharma
  35. 35. 10 commandments 3 5 https://www.healthxl.com/blog/12-commandments-for-startup-and-corporate-relationships?utm_source=twitter&utm_medium=social&utm_campaign=always-on+- +12+commandments+for+digital+health&utm_content=post+-+blog+infograph
  36. 36. www.dayone.swiss #dayonebasel LinkedIn Groups: „DayOne – Innovation Hub for Precision Medicine“

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