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Development of the Face                  Dr.Dashrath Kafle
Face At the end of the 4th week, facial prominences consisting  primarily of neural crest-derived mesenchyme appear Maxi...
Face contd... Frontonasal prominence - proliferation of mesenchyme  ventral to the brain vesicles On both sides, local t...
Face contd... During the 5th week, the nasal placodes invaginate to  form nasal pits Lateral nasal prominences Medial n...
Face contd...                7
Formation of lip The maxillary prominences grow medially, compressing medial nasal prominences towards midline, two fuse ...
Development of nose Maxillary prominences enlarge to form the cheeks and  maxilla Nose is formed from five facial promin...
Intermaxillary Segment Two medial nasal prominences merge at a deeper level  forming the intermaxillary segment Composed...
Intermaxillary Segment contd...                                  12
Secondary Palate Formed by two palatine shelves (6th week of  development) –maxillary process Directed obliquely downwar...
Secondary Palate contd...                    Nasal septum: derivative of                    Frontonasal process           ...
Secondary Palate contd... Anteriorly, the palatine shelves fuse with the primary  palate                                 ...
Development of Tongue Appear at 4 weeks As two lateral lingual swellings and one medial swelling,  the tuberculum impar ...
Tongue contd...                  19
Tongue contd... Lateral lingual swellings increase in size, overgrow the  tuberculum impar and merge, forming the anterio...
Tongue contd... A third median swelling, formed by the posterior part of  the fourth arch, marks development of the epigl...
Development contd....                        23
Tongue contd... The mucosa covering the body of the tongue originates  from the first pharyngeal arch Sensory innervatio...
Tongue contd... The epiglottis and the extreme posterior part of the tongue  are innervated by the superior laryngeal ner...
Tongue contd... Special sensory innervation (taste) to the anterior two  thirds of the tongue is provided by the chorda t...
Development contd.......•Circumvallate papilla-  - months• Fungiform -      weeks•Filliform – after birth•Gustatory cells-...
Development of the face
Development of the face
Development of the face
Development of the face
Development of the face
Development of the face
Development of the face
Development of the face
Development of the face
Development of the face
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Development of the face

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Development of the face

  1. 1. Development of the Face Dr.Dashrath Kafle
  2. 2. Face At the end of the 4th week, facial prominences consisting primarily of neural crest-derived mesenchyme appear Maxillary prominences- lateral to the stomodeum mandibular prominences- caudal to stomodeum 2
  3. 3. Face contd... Frontonasal prominence - proliferation of mesenchyme ventral to the brain vesicles On both sides, local thickenings of the surface ectoderm, the nasal placodes originate 3
  4. 4. Face contd... During the 5th week, the nasal placodes invaginate to form nasal pits Lateral nasal prominences Medial nasal prominences 5
  5. 5. Face contd... 7
  6. 6. Formation of lip The maxillary prominences grow medially, compressing medial nasal prominences towards midline, two fuse forming upper lip by two medial nasal prominences and two maxillary prominences 8
  7. 7. Development of nose Maxillary prominences enlarge to form the cheeks and maxilla Nose is formed from five facial prominences: - frontal prominence gives rise to bridge - merged medial nasal prominences provide the crest and tip - lateral nasal prominences form the alae 10
  8. 8. Intermaxillary Segment Two medial nasal prominences merge at a deeper level forming the intermaxillary segment Composed of (a) philtrum of the upper lip (b) upper jaw component- carries the four incisor teeth (c) primary palate 11
  9. 9. Intermaxillary Segment contd... 12
  10. 10. Secondary Palate Formed by two palatine shelves (6th week of development) –maxillary process Directed obliquely downward on each side of the tongue In the 7th week, the palatine shelves ascend to attain a horizontal position above the tongue and fuse, forming the secondary palate 13
  11. 11. Secondary Palate contd... Nasal septum: derivative of Frontonasal process 14
  12. 12. Secondary Palate contd... Anteriorly, the palatine shelves fuse with the primary palate 15
  13. 13. Development of Tongue Appear at 4 weeks As two lateral lingual swellings and one medial swelling, the tuberculum impar (all originate from the first pharyngeal arch) A second median swelling, the copula, formed by mesoderm of the second, third, and part of the fourth arch 18
  14. 14. Tongue contd... 19
  15. 15. Tongue contd... Lateral lingual swellings increase in size, overgrow the tuberculum impar and merge, forming the anterior two- thirds, or body, of the tongue The body of the tongue is separated from the posterior third by a V-shaped groove, the terminal sulcus 20
  16. 16. Tongue contd... A third median swelling, formed by the posterior part of the fourth arch, marks development of the epiglottis 22
  17. 17. Development contd.... 23
  18. 18. Tongue contd... The mucosa covering the body of the tongue originates from the first pharyngeal arch Sensory innervation to the posterior part, or root part of the tongue is supplied by the glossopharyngeal nerve 24
  19. 19. Tongue contd... The epiglottis and the extreme posterior part of the tongue are innervated by the superior laryngeal nerve, reflecting their development from the fourth arch Most tongue muscles are derived from myoblasts originating in occipital somites. So innervated by the hypoglossal nerve 25
  20. 20. Tongue contd... Special sensory innervation (taste) to the anterior two thirds of the tongue is provided by the chorda tympani branch of the facial nerve, while the posterior third is supplied by the glossopharyngeal nerve 26
  21. 21. Development contd.......•Circumvallate papilla- - months• Fungiform - weeks•Filliform – after birth•Gustatory cells- starts th week•All taste bud present atbirth except- taste bud(circumvallate papilla) 27

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