Università degli Studi di Napoli Facoltà di Medicina e Chirurgia Corso di Laurea per Tecnico della Prevenzione nell’Ambien...
Three detective stories: <ul><li>A double case of acute chemical poisoning </li></ul><ul><li>An unusual epidemics: the sho...
A double case of acute chemical poisoning Two workers were found dead in a well where they were burying barrels containing...
brain
lung
lung
<ul><li>kidney </li></ul>
<ul><li>liver </li></ul>
 
 
 
 
An unusual winter epidemics:  the shoemakers’ polyneuropathy
 
 
 
 
 
 
 
 
 
 
 
 
Two interesting cases of selective acute hepato-nephrotoxicity
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
<ul><li>In the 20’s carbon </li></ul><ul><li>tetrachloride was  </li></ul><ul><li>used to treat </li></ul><ul><li>anchilos...
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
CONCLUSIONS 1. Understanding mechanisms of toxicity may help to clarify the causes and the clinical features of human pois...
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Tossicologia ambientale e occupazionale

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Tossicologia ambientale e occupazionale

  1. 1. Università degli Studi di Napoli Facoltà di Medicina e Chirurgia Corso di Laurea per Tecnico della Prevenzione nell’Ambiente e nei Luoghi di Lavoro Corso di Medicina del Lavoro 4 Tossicologia Ambientale ed Occupazionale Docente: Prof. Maurizio Manno
  2. 2. Three detective stories: <ul><li>A double case of acute chemical poisoning </li></ul><ul><li>An unusual epidemics: the shoemakers’ polyneuropathy </li></ul><ul><li>Two interesting cases of selective acute hepato-nephrotoxicity </li></ul>
  3. 3. A double case of acute chemical poisoning Two workers were found dead in a well where they were burying barrels containing solvents and solid chemical waste from a nearby chemical plant.
  4. 4. brain
  5. 5. lung
  6. 6. lung
  7. 7. <ul><li>kidney </li></ul>
  8. 8. <ul><li>liver </li></ul>
  9. 13. An unusual winter epidemics: the shoemakers’ polyneuropathy
  10. 26. Two interesting cases of selective acute hepato-nephrotoxicity
  11. 46. <ul><li>In the 20’s carbon </li></ul><ul><li>tetrachloride was </li></ul><ul><li>used to treat </li></ul><ul><li>anchilostomiasis </li></ul><ul><li>infection </li></ul>
  12. 62. CONCLUSIONS 1. Understanding mechanisms of toxicity may help to clarify the causes and the clinical features of human poisoning. 2. Cases of human poisoning may help to validate mechanistic hypotheses developed in animal models.

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