We have created a pipeline of recently enhanced open source components for extracting chemical reactions from full text chemical literature. OSCAR4 is used to recognise chemical entities and resolve to structures where appropriate. OPSIN is used to resolve systematic chemical names to structures. Chemical Tagger performs part of speech tagging allowing the interpretation of phrases in chemical syntheses. The final output is a semantic representation (chemical components and their roles, reaction conditions, actions including workup, yield and properties of the product). We then attempt to map all atoms in the product(s) to reactants. If successful we also attempt to calculate the stoichiometry of the reaction. The system has been deployed on over 56,000 USPTO patents published since 2008. The level of recall is useful and most extracted reactions make chemical sense. The pipeline is generally applicable to reactions in chemical literature including journals and theses.