15. pasamba alopecia


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15. pasamba alopecia

  1. 1. ALOPECIAPasamba, Angillete Domirene P. DMD 2D
  2. 2. A. Definition ALOPECIAAlso known as “Baldness.” Refers to hair loss in areas of skinthat normally have hair.There are two forms of alopecia: scarringand non-scarring. • Scarring • Non-scarring
  3. 3. Hair Loss
  4. 4. B. SIGNS AND SYMPTOMSALOPECIA SYMPTOMS DEPEND ON THE TYPE OF HAIR LOSS. SOME OF THE MORE COMMON SYMPTOMS INCLUDE: Male-pattern baldness: Female-pattern baldness:•Hair recedes •Hair thins over the entire head•Hair falls out at the top of the head •Hair comes out when brushing Fungal infections:•Affects men and women •Patches of hair loss Alopecia areata: •Black dots in the patches•Rapid hair loss •Itching•Round or oval patches of hair loss •Scaling•Sometimes tiny hairs are visible in •Inflammation (such as redness)the patches Stress-related:•Fingernails and toenails with pits •Gradual shedding •Hairs come out with gentle pulling
  5. 5. C. DENTAL CORRELATION OF THE DISEASE IN DENTAL TREATMENT There is a close relationship between dental disease and hair loss, according to researchers from the Department of Stomatology at the University of Granada, (UGR) Spain. Professors José Antonio Gil Montoya and Antonio Cutando Soriano. They explained, We have found that bald patchescaused by tooth infection are not always in the same place. Theynormally appear on a line projected from the dental infection and canthus can be located on the face at the level of the maxillary teeth,above a line through the lip-angle to the scalp, beard, or even to theeyebrow. Nevertheless, they can also be located far from infectionoutbreak.
  6. 6. PRECAUTIONS• Patients with alopecia are advised to visit their dentists in order to receive a careful examination of their oral health. • If you want to minimize your hair loss, the two nutrients that you have to make sure you have plenty of every day. These nutrients are Vitamin A and Vitamin B.
  7. 7. D. CLASSIFICATION OF THE DISEASE MULTIFACTORIAL Martinez-Mir et al. (2007) suggested that alopecia fits the paradigm of a complex or multifactorial genetic trait based on several lines of evidence: its prevalence in the population of approximately 2%; concordance in twins of 55% (Jackow et al., 1998); a Gaussian distribution of severity; a 10-fold increased risk for first-degree relatives of affected individuals; and the aggregation of affected individuals in families with no clear mendelian pattern of inheritance.MappingLinkage to Chromosome 18In an effort to define a genetic basis of alopecia, Martinez-Mir et al. (2007) performed a genomewidesearch for linkage to 20 families with 102 affected and 118 unaffected individuals from the UnitedStates and Israel. The analysis revealed evidence of at least 4 susceptibility loci on chromosome 6, 10,16, and 18 using several different statistical approaches. Fine-mapping analysis with additional familiesyielded a maximum multipoint lod score of 3.93 on chromosome 18 at marker D18S967 (AA1), a 2-point affected sib pair (ASP) lod score of 3.11 on chromosome 16 (AA2; 610753), several ASP lodscores greater than 2.00 on chromosome 6q, and a haplotype-based relative risk lod of 2.00 onchromosome 6p, in the major histocompatibility complex locus.