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Super Avana (Avanafil and Dapoxetine Tablets)

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Super Avana (Avanafil and Dapoxetine Tablets)

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Super Avana Tablets, a combination of Avanafil 100 mg and Dapoxetine Hydrochloride 60 mg, is a new medication used for the treatment of male erectile dysfunction when at the same time treatment of premature ejaculation is also desirable.

Super Avana Tablets, a combination of Avanafil 100 mg and Dapoxetine Hydrochloride 60 mg, is a new medication used for the treatment of male erectile dysfunction when at the same time treatment of premature ejaculation is also desirable.

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Super Avana (Avanafil and Dapoxetine Tablets)

  1. 1. Super Avana Tablets © Clearsky Pharmacy Super Avana Tablets, a combination of Avanafil 100 mg and Dapoxetine Hydrochloride 60 mg, is a new medication used for the treatment of male erectile dysfunction when at the same time treatment of premature ejaculation is also desirable.
  2. 2. Super Avana Tablets © Clearsky Pharmacy Super Avana Tablets are manufactured by Sunrise Remedies Pvt. Ltd., India. In the strength of 160 mg (100 mg of Avanafil and 60 mg of Dapoxetine Hydrochloride) (Website: www.sunriseremedies.in)
  3. 3. Avanafil and Dapoxetine Tablets – Brand Names © Clearsky Pharmacy Avanafil and Dapoxetine combination tablets are available as Super Avana tablets.
  4. 4. Active Ingredients © Clearsky Pharmacy The active ingredients contained in Super Avana Tablets are Dapoxetine Hydrochloride and Avanafil. Each Super Avana tablet contains 60 mg of Dapoxetine Hydrochloride and 100 mg of Avanafil.
  5. 5. Chemical Structure © Clearsky Pharmacy The structure of Avanafil is given below:
  6. 6. Chemical Structure © Clearsky Pharmacy The structure of Dapoxetine HCl is given below:
  7. 7. Super Avana Tablets Dosage © Clearsky Pharmacy ➢The dosage of Super Avana is one tablet once a day. Take the tablet approximately half an hour before any sexual activity with at least one full glass of water. ➢Do not take more than 1 tablet in any 24 hour period. At least 24 hours must pass since your last dose. The dosage of Super Avana Tablets (Avanafil and Dapoxetine Hydrochloride) is given below:
  8. 8. Uses of Super Avana Tablets © Clearsky Pharmacy Super Avana is used for the treatment of male erectile dysfunction as well as treatment of premature ejaculation simultaneously in men. Avanafil, an oral medicine for erectile dysfunction, is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 and is the latest medicine to treat ED. Dapoxetine Hydrochloride, is a selective serotonin reuptake inhibitor (SSRI) which is used to treat persistent or recurrent ejaculation with minimal sexual stimulation before, on, or immediately after penetration and before the patient wishes.
  9. 9. Storage Instructions © Clearsky Pharmacy Super Avana Tablets has to be stored at controlled room temperature i.e. from 20°C to 25°C (68°F to 77°F) with excursions permitted between 15° to 30°C (59° to 86°F). Keep this as well as all other medicines away from children and pets.
  10. 10. Super Avana Tablets Warnings © Clearsky Pharmacy Super Avana Tablets (Avanafil and Dapoxetine Tablets) must not be used by patients if sexual activity is NOT advisable for them due to their cardiovascular status. Patients should seek emergency treatment if an erection lasts for more than 4 hours. Use Super Avana Tablets with caution in patients that are predisposed to priapism. Patients should stop Super Avana Tablets and seek medical care if a sudden loss of vision occurs in one or both eyes, which could be a sign of non arteritic anterior ischemic optic neuropathy (NAION). Patients should stop Super Avana Tablets and seek immediate medical attention in the event of sudden decrease or loss of hearing.
  11. 11. Super Avana Tablets Warnings © Clearsky Pharmacy Caution is advised when Super Avana tablets are co- administered with alpha-blockers or anti-hypertensives. Concomitant use can lead to hypotension. Decreased blood pressure, syncope, and prolonged erection may occur at higher Avanafil exposures. In patients taking strong CYP inhibitors, such as ritonavir, Avanafil exposure is increased and hence these patients should not use this medicine. Dizziness, disturbance in attention, syncope, blurred vision and somnolence have been reported in subjects receiving Dapoxetine, a constituent of Super Avana tablets. Patients must be advised not to use Super Avana in combination with recreational drugs such as Amyl Nitrate and Butyl Nitrate. Recreational drugs with serotonergic activity such as ketamine, methylenedioxy-methamphetamine (MDMA) and lysergic acid diethylamide (LSD) can lead to potentially serious reactions if combined with Super Avana tablets.
  12. 12. Super Avana Tablets Warnings © Clearsky Pharmacy Combining Super Avana with substantial amounts of alcohol (greater than 3 units) may lead to hypotension, increase alcohol-related neurocognitive effects and may also enhance neurocardiogenic adverse events such as syncope, thereby increasing the risk of accidental injury; therefore, patients must be advised to avoid drinking alcohol while taking Super Avana tablets. Possibly prodromal symptoms such as nausea, dizziness/lightheadedness, and diaphoresis were observed more frequently among patients treated with Dapoxetine compared to placebo. An orthostatic test should be performed before starting therapy. In case of a history of documented or suspected orthostatic reaction, treatment with Super Avana (Avanafil and Dapoxetine Tablets) MUST be avoided.
  13. 13. Super Avana Tablets Warnings © Clearsky Pharmacy Super Avana (Avanafil and Dapoxetine Tablets) must not be administered to patients with a history of mania / hypomania or bipolar disorder and should be stopped immediately in any patient who develops ANY symptoms of these disorders. Super Avana therapy should be stopped in any patient who develops seizures and avoided in patients with unstable epilepsy.
  14. 14. Super Avana Tablets © Clearsky Pharmacy Contraindications Super Avana Tablets is contraindicated in patients with a hypersensitivity to Avanafil, Dapoxetine Hydrochloride or any other component of this medication. Administration of Super Avana Tablets to patients using nitric oxide donors, such as organic nitrates or organic nitrites in any form is contraindicated. Super Avana Tablets is also contraindicated in patients with significant cardiac conditions as well as in patients for whom sexual intercourse is NOT advisable due to cardiovascular risk factors. This medication is contraindicated in men with severe hepatic impairment (decreased liver function)
  15. 15. Super Avana Tablets Side Effects © Clearsky Pharmacy ➢The most common side effects caused by Dapoxetine with an incidence rate of 5% or more are headache, dizziness, nausea, dry mouth, diarrhoea, insomnia and fatigue. ➢Most common side effects with an incidence rate of 2% or more caused by Avanafil include headache, flushing, nasal congestion, nasopharyngitis, and back pain.
  16. 16. Super Avana Overdose © Clearsky Pharmacy The overdose effects of Super Avana are a sum of the effects of both it's constituents. The overdose effects due to Avanafil include dizziness, nausea, and high blood pressure. Symptoms of overdose with Dapoxetine are somnolence, gastrointestinal disturbances such as nausea and vomiting, tachycardia, tremor, agitation and dizziness.
  17. 17. Super Avana Tablets Overdose © Clearsky Pharmacy In cases of Super Avana overdose, standard supportive measures must be adopted as required. Due to high protein binding and large volume of distribution of Dapoxetine Hydrochloride, forced diuresis, dialysis, hemoperfusion and exchange transfusion are unlikely to be of benefit. Similarly renal dialysis is not expected to accelerate clearance as Avanafil is highly bound to plasma proteins and it is not eliminated in the urine.
  18. 18. Super Avana Tablets During Pregnancy © Clearsky Pharmacy Avanafil has been classified by the US FDA as Pregnancy Category C. Dapoxetine Hydrochloride has been classified by the US FDA as Pregnancy Category C. Super Avana (Avanafil and Dapoxetine Tablets) is not indicated for use by women. There are no adequate and well-controlled studies of Avanafil or Dapoxetine conducted in pregnant women.
  19. 19. Super Avana Tablets For more details on Super Avana Tablets click here © Clearsky Pharmacy Super Avana (Avanafil and Dapoxetine Tablets) by Sunrise Remedies Pvt. Limited, India.

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