This document outlines an intervention called Healthy Start designed to improve physical activity and healthy eating in 3-5 year olds. It discusses key challenges in bridging research, policy, and practice. It provides three examples of innovative opportunities to overcome challenges: 1) collaboration with health regions on nutrition guidelines, 2) revising implementation manuals with public health nutritionists, and 3) implementing Healthy Start at a daycare by appointing staff, creating active spaces, and improving menus. The knowledge mobilization approach emphasizes reuse of existing knowledge, networks, multiple levels of engagement from frontline to policy, and continual revision based on feedback.