Scientific Curation: Untangling research data

49,877 views

Published on

These slides are from a presentation given by Dr Jackie MacArthur as part of the 2015 season of Careers After Biological Science at the University of Leicester (UK)

Published in: Career
0 Comments
0 Likes
Statistics
Notes
  • Be the first to comment

  • Be the first to like this

No Downloads
Views
Total views
49,877
On SlideShare
0
From Embeds
0
Number of Embeds
44,596
Actions
Shares
0
Downloads
0
Comments
0
Likes
0
Embeds 0
No embeds

No notes for slide

Scientific Curation: Untangling research data

  1. 1. Scientific curation Untangling research data Jackie MacArthur Project Leader (GWAS Catalog) www.ebi.ac.uk
  2. 2. Summary •  Current role •  Scientific Curator •  Project Leader (GWAS Catalog) •  Career path •  PhD •  Postdoctoral research •  Advice
  3. 3. GWAS Catalog scientific curator/project leader •  Scientific curator – 3 years •  Project leader – from September 2014 •  European Bioinformatics Institute (EMBL-EBI) •  Hinxton, 10 miles south of Cambridge
  4. 4. What is a scientific curator? •  Curator •  a keeper or custodian of a museum or other collection •  Scientific curator •  “museum catalogers of the Internet age”* (* Bourne et al., 2006; Burge et al., 2012)
  5. 5. GWAS Catalog •  The GWAS Catalog is a manually curated, literature-derived collection of all genome wide association studies and significant associations (http://www.genome.gov/gwastudies/) •  As of January 2015 the Catalog includes 2,100 publications and 15,257 SNPs
  6. 6. http://www.ebi.ac.uk/fgpt/gwas/
  7. 7. http://www.ebi.ac.uk/fgpt/gwas/
  8. 8. http://www.ebi.ac.uk/fgpt/gwas/
  9. 9. Scientific curator •  Identification of GWAS publications •  Reading publications and extraction of data into curation interface •  Study design and methods •  Association results •  Checking and public release of data •  Working collaboratively as part of an International team of scientists
  10. 10. GWAS Project Leader •  Improving availability of data for users •  User interface •  Scientific content •  Preparing scientific reports, publications and presentations •  GWAS Catalog outreach and promotion •  Answering queries from GWAS Catalog users and other curators •  Organising and chairing meetings •  Training curation staff •  Managing curation workload
  11. 11. Scientific curator – person requirements •  MSc or PhD in life sciences or genetics •  In depth understanding of genetic variation and genomics •  Enjoy reading scientific papers •  Attention to detail •  Good organisation and time management skills •  Self motivation
  12. 12. BSc to scientific curator BSc Biological Sciences (Genetics) Leicester UniversityPhD Nottingham University Postdoc 1 Newcastle University Postdoc 2 University California San Francisco Postdoc 3 Sanger Institute Scientific Curator EBI Project Leader (GWAS Catalog) EBI
  13. 13. PhD •  “Evolution and population genetics of the H-ras minisatellite” •  Develop research skills and scientific knowledge •  Experience managing a project •  Experience working in academic environment •  Needs to be the right project!
  14. 14. Postdoctoral academia •  Newcastle University •  Genetic alterations involved in medulloblastoma development •  University of California, San Francisco •  Using array CGH to analyse copy number variation •  Wellcome Trust Sanger Institute •  Mechanisms of chromosomal rearrangement leading to genomic disorders
  15. 15. Why do a Postdoc if you don’t want to stay in academia? •  Experience working in research/science •  Project management skills •  Networking – getting to know more people in science •  Transferrable skills •  Problem solving •  Analytical skills •  Opportunities to develop additional skills depending on your interests/career goals
  16. 16. Leaving research •  It was never my goal to stay in research/academia •  I wanted an interesting job in science that fitted in with my personal life Was this a good choice? •  Using scientific expertise and experience •  Looking at the bigger picture •  Benefitting the scientific community •  Still get to publish and present work at conferences •  Still not a permanent position
  17. 17. Advice – jobs in science outside research •  Get a PhD •  Build up a network •  Do what you find interesting •  Think about what your skills are/what you enjoy and try to match these to a job •  Keep an open mind – the job you are suited to may not exist yet •  Think about the priorities in your life
  18. 18. Questions?

×