Successfully reported this slideshow.
We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. You can change your ad preferences anytime.
Last data updates: 12 November 2010
Huang, M.E., Ye, Y.C., Chen, S.R., Chai, J.R., Lu, J.X., Zhoa, L., Gu, L.J. and Wang, ...
2
15. Hughes, P.J., Marcinkowska, E., Gocek, E., Studzinski, G.P. and Brown, G. (2010), Vitamin
D-3-driven signals for mye...
3
32. Sugitani, M., Abe, R., Ikarashi, N., Ito, K., Muratake, H., Shudo, K. and Sugiyama, K. (2009),
Disposition of a New ...
4
Promyelocytic Leukemia with t(15;17): a Case Report and Review of the Literature. Puerto
Rico Health Sciences Journal, 2...
5
63. Fang, H., Wang, K. and Zhang, J. (2008), Transcriptome and Proteome Analyses of Drug
Interactions with Natural Produ...
6
81. Wall, M., Poortinga, G., Hannan, K.M., Pearson, R.B., Hannan, R.D. and McArthur, G.A.
(2008), Translational control ...
7
97. Wang, L., Zhou, G.B., Liu, P., Song, J.H., Liang, Y., Yan, X.J., Xu, F., Wang, B.S., Mao, J.H.,
Shen, Z.X., Chen, S....
8
116. Dilda, P.J. and Hogg, P.J. (2007), Arsenical-based cancer drugs. Cancer Treatment Reviews,
33 (6), 542-564.
117. Ho...
9
134. Si, J.T., Mueller, L. and Collins, S.J. (2007), CaMKII regulates retinoic acid receptor
transcriptional activity an...
10
150. Ohnuma-Ishikawa, K., Morio, T., Yamada, T., Sugawara, Y., Ono, M., Nagasawa, M., Yasuda,
A., Morimoto, C., Ohnuma,...
11
165. Kizaki, M., Xian, M.J., Sagawa, M. and Ikeda, Y. (2006), Induction of apoptosis via the
modulation of reactive oxy...
12
181. Kizaki, M. (2006), New therapeutic approach for myeloid leukemia: Induction of apoptosis via
modulation of reactiv...
13
197. Wang, Y.A., Shen, K., Ishida, Y., Wang, Y.L., Kakizuka, A. and Brooks, S.C. (2005),
Induction of murine leukemia a...
14
corepressor/coactivator exchange with retinoic acid receptor alpha and enhancing changes in
all-trans-retinoic acid-reg...
15
229. Kumagai, T., Shih, L.Y., Hughes, S.V., Desmond, J.C., O'Kelly, J., Hewison, M. and Koeffler,
H.P. (2005), 19-Nor-1...
16
245. Hu, L.D., Tang, X. and Cui, F.D. (2004), Solid lipid namoparticles (SLNs) to improve oral
bioavailability of poorl...
17
261. Lei, M. and de The, H. (2003), Retinoids and retinoic acid receptor in cancer. Ejc Supplements,
1 (2), 13-18.
262....
18
278. Jeong, Y.I., Kang, M.K., Sun, H.S., Kang, S.S., Kim, H.W., Moon, K.S., Lee, K.J., Kim, S.H.
and Jung, S. (2004), A...
19
296. Jing, Y.K. (2004), The PML-RAR alpha fusion protein and targeted therapy for acute
promyelocytic leukemia. Leukemi...
20
313. Lengfelder, E., Gnad, U., Buchner, T. and Hehlmann, R. (2003), Treatment of relapsed acute
promyelocytic leukemia....
21
330. Takahashi, N., Tamagawa, K., Shimizu, K., Fukui, T. and Maitani, Y. (2003), Effects on
M5076-hepatic metastasis of...
22
348. Lanvers, C., Reinhardt, D., Dubbers, A., Wagner-Bohn, A., Creutzig, U., Ritter, J. and Boos, J.
(2003), Pharmacolo...
23
364. Okuno, M., Kojima, S. and Moriwaki, H. (2001), Chemoprevention of hepatocellular
carcinoma: Concept, progress and ...
24
383. Muller, P., Kietz, S., Gustafsson, J.A. and Strom, A. (2002), The anti-estrogenic effect of
all-trans-retinoic aci...
25
398. Sakamoto, O., Yoshinari, M., Rikiishi, T., Fujiwara, I., Imaizumi, M., Tsuchiya, S. and Iinuma,
K. (2001), Hyperca...
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Times Cited - 08/22/2010 03:17:40 pm  0800 - iso-8859-1 - OpenWebMail
Upcoming SlideShare
Loading in …5
×

Times Cited - 08/22/2010 03:17:40 pm 0800 - iso-8859-1 - OpenWebMail

3,798 views

Published on

  • Be the first to comment

  • Be the first to like this

Times Cited - 08/22/2010 03:17:40 pm 0800 - iso-8859-1 - OpenWebMail

  1. 1. Last data updates: 12 November 2010 Huang, M.E., Ye, Y.C., Chen, S.R., Chai, J.R., Lu, J.X., Zhoa, L., Gu, L.J. and Wang, Z.Y. (1988), Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia. Blood, 72 (2), 567-572. Document type: Article Language: English Cited references: 25 Times cited: 1544 Times self cited: 47 Addresses: 1. Shanghai Med Univ 2, Shanghai Inst Hematol, 280 S Chong Qing Rd, Shanghai, Peoples R China 2. Shanghai Zhong Shan Hosp, Shanghai, Peoples R China 3. Shanghai Childrens Hosp, Shanghai, Peoples R China 1. de The, H. and Chen, Z. (2010), Acute promyelocytic leukaemia: novel insights into the mechanisms of cure. Nature Reviews Cancer, 10 (11), 775-783. 2. Jung, E.U., Yoon, J.H., Lee, Y.J., Lee, J.H., Kim, B.H., Yu, S.J., Myung, S.J., Kim, Y.J. and Lee, H.S. (2010), Hypoxia and retinoic acid-inducible NDRG1 expression is responsible for doxorubicin and retinoic acid resistance in hepatocellular carcinoma cells. Cancer Letters, 298 (1), 9-15. 3. David, K.A., Mongan, N.P., Smith, C., Gudas, L.J. and Nanus, D.M. (2010), Phase I trial of ATRA-IV and depakote in patients with advanced solid tumor malignancies. Cancer Biology & Therapy, 9 (9), 678-684. 4. Hofmann, A., Gerrits, B., Schmidt, A., Bock, T., Bausch-Fluck, D., Aebersold, R. and Wollscheid, B. (2010), Proteomic cell surface phenotyping of differentiating acute myeloid leukemia cells. Blood, 116 (13), E26-E34. 5. Nayak, S., Shen, M.Q., Bunaciu, R.P., Bloom, S.E., Varner, J.D. and Yen, A. (2010), Arsenic trioxide cooperates with all-trans retinoic acid to enhance mitogen-activated protein kinase activation and differentiation in PML-RAR alpha negative human myeloblastic leukemia cells. Leukemia & Lymphoma, 51 (9), 1734-1747. 6. Li, Y., Lu, H.M., Huang, Y.J., Xiao, R., Cai, X.F., He, S.M. and Yan, G.M. (2010), Glycogen synthase kinases-3 beta controls differentiation of malignant glioma cells. International Journal of Cancer, 127 (6), 1271-1282. 7. Pinkel, D. (2010), Mutation Analysis for Runx1, Mll-Ptd, Flt3-Itd, Npm1 and Nras in 269 Patients with Mds Or Secondary Aml Response. Leukemia, 24 (8), 1532-1533. 8. Thatcher, J.E., Zelter, A. and Isoherranen, N. (2010), The relative importance of CYP26A1 in hepatic clearance of all-trans retinoic acid. Biochemical Pharmacology, 80 (6), 903-912. 9. Lee, J.H., Yoon, J.H., Yu, S.J., Chung, G.E., Jung, E.U., Kim, H.Y., Kim, B.H., Choi, D.H., Myung, S.J., Kim, Y.J., Kim, C.Y. and Lee, H.S. (2010), Retinoic acid and its binding protein modulate apoptotic signals in hypoxic hepatocellular carcinoma cells. Cancer Letters, 295 (2), 229-235. 10. Zhao, J., Jiang, P. and Zhang, W.D. (2010), Molecular networks for the study of TCM Pharmacology. Briefings in Bioinformatics, 11 (4), 417-430. 11. Burda, P., Laslo, P. and Stopka, T. (2010), The role of PU.1 and GATA-1 transcription factors during normal and leukemogenic hematopoiesis. Leukemia, 24 (7), 1249-1257. 12. Nasr, R. and de The, H. (2010), Eradication of acute promyelocytic leukemia-initiating cells by PML/RARA-targeting. International Journal of Hematology, 91 (5), 742-747. 13. Song, X.M., Gong, S.L., Chen, J., Gao, L., Yang, J.M. and Wang, J.M. (2010), ATRA is effective to an acute promyelocytic leukemia patient without RARA gene rearrangement. Leukemia Research, 34 (8), E190-E193. 14. Pedersen, P.J., Adolph, S.K., Subramanian, A.K., Arouri, A., Andresen, T.L., Mouritsen, O.G., Madsen, R., Madsen, M.W., Peters, G.H. and Clausen, M.H. (2010), Liposomal Formulation of Retinoids Designed for Enzyme Triggered Release. Journal of Medicinal Chemistry, 53 (9), 3782-3792.
  2. 2. 2 15. Hughes, P.J., Marcinkowska, E., Gocek, E., Studzinski, G.P. and Brown, G. (2010), Vitamin D-3-driven signals for myeloid cell differentiation-Implications for differentiation therapy. Leukemia Research, 34 (5), 553-565. 16. Gocek, E., Kielbinski, M., Baurska, H., Haus, O., Kutner, A. and Marcinkowska, E. (2010), Different susceptibilities to 1,25-dihydroxyvitamin D-3-induced differentiation of AML cells carrying various mutations. Leukemia Research, 34 (5), 649-657. 17. Theodosiou, M., Laudet, V. and Schubert, M. (2010), From carrot to clinic: an overview of the retinoic acid signaling pathway. Cellular and Molecular Life Sciences, 67 (9), 1423-1445. 18. Zhang, X.W., Yan, X.J., Zhou, Z.R., Yang, F.F., Wu, Z.Y., Sun, H.B., Liang, W.X., Song, A.X., Lallemand-Breitenbach, V., Jeanne, M., Zhang, Q.Y., Yang, H.Y., Huang, Q.H., Zhou, G.B., Tong, J.H., Zhang, Y., Wu, J.H., Hu, H.Y., de The, H., Chen, S.J. and Chen, Z. (2010), Arsenic Trioxide Controls the Fate of the PML-RAR alpha Oncoprotein by Directly Binding PML. Science, 328 (5975), 240-243. 19. Karnaukhova, E. (2010), Interactions of alpha(1)-proteinase inhibitor with small ligands of therapeutic potential: binding with retinoic acid. Amino Acids, 38 (4), 1011-1020. 20. Takahashi, N. (2010), Vitamin A in Health. Journal of Health Science, 56 (2), 144-153. 21. Puppi, D., Piras, A.M., Detta, N., Dinucci, D. and Chiellini, F. (2010), Poly(lactic-co-glycolic acid) electrospun fibrous meshes for the controlled release of retinoic acid. Acta Biomaterialia, 6 (4), 1258-1268. 22. Li, Y., Lu, H.M., Li, G. and Yan, G.M. (2010), Glycogen synthase kinase-3 beta regulates astrocytic differentiation of U87-MG human glioblastoma cells. Acta Pharmacologica Sinica, 31 (3), 355-360. 23. Trinks, C., Djerf, E.A., Hallbeck, A.L., Jonsson, J.I. and Walz, T.M. (2010), The pan-ErbB receptor tyrosine kinase inhibitor canertinib induces ErbB-independent apoptosis in human leukemia (HL-60 and U-937) cells. Biochemical and Biophysical Research Communications, 393 (1), 6-10. 24. Ferrara, F. (2010), Acute promyelocytic leukemia: what are the treatment options? Expert Opinion on Pharmacotherapy, 11 (4), 587-596. 25. Miyoshi, T., Arai, T., Yamashita, K., Sasada, M. and Uchiyama, T. (2010), NB4 cells treated with all-trans retinoic acid generate toxic reactive oxygen species that cause endothelial hyperpermeability. Leukemia Research, 34 (3), 373-378. 26. Kinoshita, K., Kishimoto, K., Shimazu, H., Nozaki, Y., Sugiyama, M., Ikoma, S. and Funauchi, M. (2010), Successful Treatment With Retinoids in Patients With Lupus Nephritis. American Journal of Kidney Diseases, 55 (2), 344-347. 27. Chen, J.J., Odenike, O. and Rowley, J.D. (2010), Epigenetics and Genetics Leukaemogenesis: More Than Mutant Genes. Nature Reviews Cancer, 10 (1), 23-36. 28. Miyoshi, N., Ishii, H., Nagai, K., Hoshino, H., Mimori, K., Tanaka, F., Nagano, H., Sekimoto, M., Doki, Y. and Mori, M. (2010), Defined factors induce reprogramming of gastrointestinal cancer cells. Proceedings of the National Academy of Sciences of the United States of America, 107 (1), 40-45. 29. Chute, J.P., Ross, J.R. and McDonnell, D.P. (2010), Minireview: Nuclear Receptors, Hematopoiesis, and Stem Cells. Molecular Endocrinology, 24 (1), 1-10. 30. Watanabe, M., Chen, I.Y.J., Ishikura, Y., Nakagawa, T., Mochizuki, M., Nishimura, R., Sasaki, N. and Sugano, S. (2009), Tumor Cell Growth Inhibition and Cell Differentiation Analysis in a Canine Mammary Tumor Cell Line (MCM-B2) Treated with Four Chemical Reagents. Journal of Veterinary Medical Science, 71 (11), 1413-1417. 31. Trojanowicz, B., Winkler, A., Hammje, K., Chen, Z.X., Sekulla, C., Glanz, D., Schmutzler, C., Mentrup, B., Hombach-Klonisch, S., Klonisch, T., Finke, R., Kohrle, J., Dralle, H. and Hoang-Vu, C. (2009), Retinoic acid-mediated down-regulation of ENO1/MBP-1 gene products caused decreased invasiveness of the follicular thyroid carcinoma cell lines. Journal of Molecular Endocrinology, 42 (3-4), 249-260.
  3. 3. 3 32. Sugitani, M., Abe, R., Ikarashi, N., Ito, K., Muratake, H., Shudo, K. and Sugiyama, K. (2009), Disposition of a New Tamibarotene Prodrug in Mice. Biological & Pharmaceutical Bulletin, 32 (12), 1997-2001. 33. Walter, M.J., Graubert, T.A., Dipersio, J.F., Mardis, E.R., Wilson, R.K. and Ley, T.J. (2009), Next-generation sequencing of cancer genomes: back to the future. Personalized Medicine, 6 (6), 653-662. 34. Chen, G.Q., Zhang, J. and Zhao, Q. (2009), Active compounds-based discoveries about the differentiation and apoptosis of leukemic cells. Chinese Science Bulletin, 54 (22), 4094-4101. 35. Xu, D., Huang, Y.J., Li, Y., Yin, W. and Yan, G.M. (2009), Orphan nuclear receptor Nur77 is required for the differentiation of C6 glioma cells induced by cholera toxin. Acta Pharmacologica Sinica, 30 (11), 1543-1549. 36. Takahashi, N. and Ohba, T. (2009), Demonstration of Basic Proteins That Bind Retinoic Acid in the Human Myeloid Leukemia Cell Line HL60. Biological & Pharmaceutical Bulletin, 32 (11), 1943-1946. 37. Togano, T., Sasaki, M., Watanabe, M., Nakashima, M., Tsuruo, T., Umezawa, K., Higashihara, M., Watanabe, T. and Horie, R. (2009), Induction of oncogene addiction shift to NF-kappa B by camptothecin in solid tumor cells. Biochemical and Biophysical Research Communications, 390 (1), 60-64. 38. Cellai, C., Laurenzana, A., Bianchi, E., Sdelci, S., Manfredini, R., Vannucchi, A.M., Caporale, R., Balliu, M., Mannelli, F., Ferrari, S., Bosi, A., Miniati, D., Cocco, P.L., Veronneau, S., Stankova, J. and Paoletti, F. (2009), Mechanistic insight into WEB-2170-induced apoptosis in human acute myelogenous leukemia cells: The crucial role of PTEN. Experimental Hematology, 37 (10), 1176-1185. 39. Krcmova, L., Urbanek, L., Solichova, D., Kasparova, M., Vlckova, H., Melichar, B., Sobotka, L. and Solich, P. (2009), HPLC method for simultaneous determination of retinoids and tocopherols in human serum for monitoring of anticancer therapy. Journal of Separation Science, 32 (15-16), 2804-2811. 40. Wang, W.J., Zhang, X.M., Deng, K.Y., Huang, S.F., Mao, X.Q., Fu, Y.R., Yi, Z.J., Yan, Y.R. and Qiu, Z.Y. (2009), ICAT as a potential enhancer of monocytic differentiation: implications from the comparative proteome analysis of the HL60 cell line stimulated by all-trans retinoic acid and NSC67657. Cell Biochemistry and Function, 27 (6), 329-337. 41. Ballard, J.O. (2009), More Things in Heaven and Earth. Jama-Journal of the American Medical Association, 302 (7), 723-724. 42. Thatcher, J.E. and Isoherranen, N. (2009), The role of CYP26 enzymes in retinoic acid clearance. Expert Opinion on Drug Metabolism & Toxicology, 5 (8), 875-886. 43. Ishiguro, K., Rice, A.M., Rice, K.P. and Sartorelli, A.C. (2009), Inhibition of all-trans retinoic acid-induced granulocytic differentiation of WEHI-3B D+ cells by forced expression of SCL (TAL1) and GATA-1. Leukemia Research, 33 (9), 1249-1254. 44. Burande, C.F., Heuze, M.L., Lamsoul, I., Monsarrat, B., Uttenweiler-Joseph, S. and Lutz, P.G. (2009), A Label-free Quantitative Proteomics Strategy to Identify E3 Ubiquitin Ligase Substrates Targeted to Proteasome Degradation. Molecular & Cellular Proteomics, 8 (7), 1719-1727. 45. Silberberg, Y.R., Yakubov, G.E., Horton, M.A. and Pelling, A.E. (2009), Cell nanomechanics and focal adhesions are regulated by retinol and conjugated linoleic acid in a dose-dependent manner. Nanotechnology, 20 (28. 46. Guo, Y.X., Zheng, G.H., Jin, X.Q., Xu, Y.H., Luo, Q., Liu, X.M., Zhao, Z.Z. and Chen, Y. (2009), HA117 gene increased the multidrug resistance of K562 cells in vitro: an investigation to the function of a novel gene related to drug resistance. Journal of Experimental & Clinical Cancer Research, 28. 47. Betancourt-Garcia, R.D., Castro, J., Fernandez, A.C., Lopez-Enriquez, A., Fradera, J. and Pacheco, E. (2009), Acquired Acute Myelogenous Leukemia after Therapy for Acute
  4. 4. 4 Promyelocytic Leukemia with t(15;17): a Case Report and Review of the Literature. Puerto Rico Health Sciences Journal, 28 (2), 146-150. 48. Montillo, M., Ricci, F., Tedeschi, A., Cafro, A.M., Nosari, A.M., Nichelatti, M., Marbello, L. and Morra, E. (2009), Twice daily fludarabine/Ara-C associated to idarubicin, G-CSF and ATRA is an effective salvage regimen in non-promyelocytic acute myeloid leukemia. Leukemia Research, 33 (8), 1072-1078. 49. Kelaidi, C., Chevret, S., De Botton, S., Raffoux, E., Guerci, A., Thomas, X., Pigneux, A., Lamy, T., Rigal-Huguet, F., Meyer-Monard, S., Chevallier, P., Maloisel, F., Deconinck, E., Ferrant, A., Fegueux, N., Ifrah, N., Sanz, M., Dombret, H., Fenaux, P. and Ades, L. (2009), Improved Outcome of Acute Promyelocytic Leukemia With High WBC Counts Over the Last 15 Years: The European APL Group Experience. Journal of Clinical Oncology, 27 (16), 2668-2676. 50. Barber, N., Gez, S., Belov, L., Mulligan, S.P., Woolfson, A. and Christopherson, R.I. (2009), Profiling CD antigens on leukaemias with an antibody microarray. Febs Letters, 583 (11), 1785-1791. 51. Baxter, S.S., Carlson, L.A., Mayer, A.M.S., Hall, M.L. and Fay, M.J. (2009), Granulocytic differentiation of HL-60 promyelocytic leukemia cells is associated with increased expression of Cul5. In Vitro Cellular & Developmental Biology-Animal, 45 (5-6), 264-274. 52. Zhang, X.Z., Li, X.J., Ji, H.F. and Zhang, H.Y. (2009), Impact of drug discovery on stem cell biology. Biochemical and Biophysical Research Communications, 383 (3), 275-279. 53. Stuart, D. and Sellers, W. (2009), Linking somatic genetic alterations in cancer to therapeutics. Current Opinion in Cell Biology, 21 (2), 304-310. 54. Wang, Y.L., Song, D.D., Li, Z.L., Yuan, T., Zhang, H.L., Pei, Y.H., Jing, Y.K. and Hua, H.M. (2009), Triterpenoids isolated from the aerial parts of Salvia chinensis. Phytochemistry Letters, 2 (2), 81-84. 55. Deville, L., Hillion, J. and Segal-Bendirdjian, E. (2009), Telomerase regulation in hematological cancers: A matter of stemness? Biochimica et Biophysica Acta-Molecular Basis of Disease, 1792 (4), 229-239. 56. Nowak, D., Stewart, D. and Koeffler, H.P. (2009), Differentiation therapy of leukemia: 3 decades of development. Blood, 113 (16), 3655-3665. 57. Tsumura, H., Akimoto, M., Kiyota, H., Ishii, Y., Ishikura, H. and Honma, Y. (2009), Gene expression profiles in differentiating leukemia cells induced by methyl jasmonate are similar to those of cytokinins and methyl jasmonate analogs induce the differentiation of human leukemia cells in primary culture. Leukemia, 23 (4), 753-760. 58. Raif, A., Marshall, G.M., Bell, J.L., Koach, J., Tan, O., D'andreti, C., Thomas, W., Sekyere, E., Norris, M., Haber, M., Kavallaris, M. and Cheung, B.B. (2009), The estrogen-responsive B box protein (EBBP) restores retinoid sensitivity in retinoid-resistant cancer cells via effects on histone acetylation. Cancer Letters, 277 (1), 82-90. 59. Dai, C.W., Zhang, G.S., Shen, J.K., Zheng, W.L., Pei, M.F., Xu, Y.X., Cao, Y.X., Yi, Y., Yang, J.J., Peng, H.L., Zhong, H.Y. and Li, R.J. (2009), Use of All-trans Retinoic Acid in Combination with Arsenic Trioxide for Remission Induction in Patients with Newly Diagnosed Acute Promyelocytic Leukemia and for Consolidation/Maintenance in CR Patients. Acta Haematologica, 121 (1), 1-8. 60. Petrie, K., Zelent, A. and Waxman, S. (2009), Differentiation therapy of acute myeloid leukemia: past, present and future. Current Opinion in Hematology, 16 (2), 84-91. 61. Hu, J., Liu, Y.F., Wu, C.F., Xu, F., Shen, Z.X., Zhu, Y.M., Li, J.M., Tang, W., Zhao, W.L., Wu, W., Sun, H.P., Chen, Q.S., Chen, B., Zhou, G.B., Zelent, A., Waxman, S., Wang, Z.Y., Chen, S.J. and Chen, Z. (2009), Long-term efficacy and safety of all-trans retinoic acid/arsenic trioxide-based therapy in newly diagnosed acute promyelocytic leukemia. Proceedings of the National Academy of Sciences of the United States of America, 106 (9), 3342-3347. 62. Telerman, A. and Amson, R. (2009), The molecular programme of tumour reversion: the steps beyond malignant transformation. Nature Reviews Cancer, 9 (3), 206-215.
  5. 5. 5 63. Fang, H., Wang, K. and Zhang, J. (2008), Transcriptome and Proteome Analyses of Drug Interactions with Natural Products. Current Drug Metabolism, 9 (10), 1038-1048. 64. Ravandi, F., Estey, E., Jones, D., Faderl, S., O'Brien, S., Fiorentino, J., Pierce, S., Blamble, D., Estrov, Z., Wierda, W., Ferrajoli, A., Verstovsek, S., Garcia-Manero, G., Cortes, J. and Kantarjian, H. (2009), Effective Treatment of Acute Promyelocytic Leukemia With All-Trans-Retinoic Acid, Arsenic Trioxide, and Gemtuzumab Ozogamicin. Journal of Clinical Oncology, 27 (4), 504-510. 65. Kumagai, T., Akagi, T., Desmond, J.C., Kawamata, N., Gery, S., Imai, Y., Song, J.H., Gui, D., Said, J. and Koeffler, H.P. (2009), Epigenetic regulation and molecular characterization of C/EBP alpha in pancreatic cancer cells. International Journal of Cancer, 124 (4), 827-833. 66. Jeong, Y.I., Kim, D.G., Jang, M.K., Nah, J.W. and Kim, Y.B. (2008), All-trans Retinoic Acid Release from Surfactant-free Nanoparticles of Poly(DL-lactide-co-glycolide). Macromolecular Research, 16 (8), 717-724. 67. Batty, E., Jensen, K. and Freemont, P. (2009), PML nuclear bodies and their spatial relationships in the mammalian cell nucleus. Frontiers in Bioscience, 14), 1182-11U7. 68. Brown, N.J.M., Ramalho, M., Pedersen, E.W., Moravcsik, E., Solomon, E. and Grimwade, D. (2009), PML nuclear bodies in the pathogenesis of acute promyelocytic leukemia: active players or innocent bystanders? Frontiers in Bioscience, 14), 1684-1707. 69. Tefferi, A. (2008), The history of myeloproliferative disorders: before and after Dameshek. Leukemia, 22), 3-13. 70. Iiizumi, M., Liu, W., Pai, S.K., Furuta, E. and Watabe, K. (2008), Drug development against metastasis-related genes and their pathways: A rationale for cancer therapy. Biochimica et Biophysica Acta-Reviews on Cancer, 1786 (2), 87-104. 71. Chow, J. and Feusner, J. (2009), Isolated Central Nervous System Recurrence of Acute Promyelocytic Leukemia in Children. Pediatric Blood & Cancer, 52 (1), 11-13. 72. Bobe, P. and Chelbi-Alix, M.K. (2008), New therapeutic perspectives for Arsenic: from acute promyelocytic leukemia to autoimmune diseases. M S-Medecine Sciences, 24 (11), 967-971. 73. Lien, J.C., Jiang, Y.D., Chen, C.J., Kuo, S.C. and Huang, L.J. (2008), Effect of Indole-3-acetic Acid Analogs on the Differentiation of HL-60 Cells. Journal of the Chinese Chemical Society, 55 (5), 1160-1165. 74. Asou, N. (2007), All-trans Retinoic Acid in the Treatment of Acute Promyelocytic Leukemia. Internal Medicine, 46 (2), 91-93. 75. Guan, L.Y., Huang, F., Li, Z.S., Han, B.S., Fiang, Q., Ren, Y., Yang, Y. and Xu, C.M. (2008), P53 transcription-independent activity mediates selenite-induced acute promyelocytic leukemia NB4 cell apoptosis. Bmb Reports, 41 (10), 745-750. 76. Yin, C., Lin, Y., Zhang, X., Chen, Y.X., Zeng, X., Yue, H.Y., Hou, J.L., Deng, X., Zhang, J.P., Han, Z.G. and Xie, W.F. (2008), Differentiation Therapy of Hepatocellular Carcinoma in Mice with Recombinant Adenovirus Carrying Hepatocyte Nuclear Factor-4 alpha Gene. Hepatology, 48 (5), 1528-1539. 77. Kim, S.H., Danilenko, M. and Kim, T.S. (2008), Differential enhancement of leukaemia cell differentiation without elevation of intracellular calcium by plant-derived sesquiterpene lactone compounds. British Journal of Pharmacology, 155 (6), 814-825. 78. Uchida, H., Inokuchi, K., Watanabe, R., Tokuhira, M. and Kizaki, M. (2008), New therapeutic approaches to acute myeloid leukemia. Expert Opinion on Drug Discovery, 3 (6), 689-706. 79. Kubo, Y., Ohba, T. and Takahashi, N. (2008), Proteins in human myeloid leukemia cell line HL60 reacting with retinoic acid monoclonal antibodies. Journal of Biochemistry, 144 (3), 349-355. 80. Zhang, H.W., Yang, Y., Zhang, K., Qiang, L., Yang, L., Yang, L., Hu, Y., Wang, X.T., You, Q.D. and Guo, Q.L. (2008), Wogonin induced differentiation and G1 phase arrest of human U-937 leukemia cells via PKC delta phosphorylation. European Journal of Pharmacology, 591 (1-3), 7-12.
  6. 6. 6 81. Wall, M., Poortinga, G., Hannan, K.M., Pearson, R.B., Hannan, R.D. and McArthur, G.A. (2008), Translational control of c-MYC by rapamycin promotes terminal myeloid differentiation. Blood, 112 (6), 2305-2317. 82. Park, J.S., Koh, Y.S., Bang, J.Y., Jeong, Y.I. and Lee, J.J. (2008), Antitumor effect of all-trans retinoic acid-encapsulated nanoparticles of methoxy poly(ethylene glycol)-conjugated chitosan against CT-26 colon carcinoma in vitro. Journal of Pharmaceutical Sciences, 97 (9), 4011-4019. 83. Bench, B.J., Tichy, S.E., Perez, L.M., Benson, J. and Watanabe, C.M.H. (2008), Synthesis and cellular effects of cycloterpenals: Cyclohexadienal-based activators of neurite outgrowth. Bioorganic & Medicinal Chemistry, 16 (16), 7573-7581. 84. Pezo, R.C. and Singer, R.H. (2008), Nuclear microenvironments in cancer diagnosis and treatment. Journal of Cellular Biochemistry, 104 (6), 1953-1963. 85. Lubbert, M., Muller-Tidow, C., Hofmann, W.K. and Koeffler, H.P. (2008), Advances in the treatment of acute myeloid leukemia: From chromosomal aberrations to biologically targeted therapy. Journal of Cellular Biochemistry, 104 (6), 2059-2070. 86. Kafka, E.L., Braden, A. and Vishwanatha, J.K. (2008), Characterization of nanoparticle-mediated drug delivery to NB4: Feasibility of nanoparticle use for cells in suspension and blood diseases. Journal of Biomedical Nanotechnology, 4 (2), 196-202. 87. Mollinedo, F., Lopez-Perez, R. and Gajate, C. (2008), Differential gene expression patterns coupled to commitment and acquisition of phenotypic hallmarks during neutrophil differentiation of human leukaemia HL-60 cells. Gene, 419 (1-2), 16-26. 88. Litzow, M.R. (2008), Arsenic trioxide. Expert Opinion on Pharmacotherapy, 9 (10), 1773-1785. 89. Park, S.J., Kim, M., Kim, N.H., Oh, M.K., Cho, J.K., Jin, J.Y. and Kim, I.S. (2008), Auranofin promotes retinoic acid- or dihydroxyvitamin D-3-mediated cell differentiation of promyelocytic leukaemia cells by increasing histone acetylation. British Journal of Pharmacology, 154 (6), 1196-1205. 90. Ozpolat, B., Akar, U., Zorrilla-Calancha, I., Vivas-Mejia, P., cevedo-Alvarez, M. and Lopez-Berestein, G. (2008), Death-associated protein 5 (DAP5/p97/NAT1) contributes to retinoic acid-induced granulocytic differentiation and arsenic trioxide-induced apoptosis in acute promyelocytic leukemia. Apoptosis, 13 (7), 915-928. 91. Scholl, S., Bondeva, T., Liu, Y., Clement, J.H., Hoffken, K. and Wetzker, R. (2008), Additive effects of PI3-kinase and MAPK activities on NB4 cell granulocyte differentiation: potential role of phosphatidylinositol 3-kinase gamma. Journal of Cancer Research and Clinical Oncology, 134 (8), 861-872. 92. Zimber, A. and Gespach, C. (2008), Bile acids and derivatives, their nuclear receptors FXR, PXR and ligands: Role in health and disease and their therapeutic potential. Anti-Cancer Agents in Medicinal Chemistry, 8 (5), 540-563. 93. Horie, A., Akimoto, M., Tsumura, H., Makishima, M., Taketani, T., Yamaguchi, S. and Honma, Y. (2008), Induction of differentiation of myeloid leukemia cells in primary culture in response to lithocholic acid acetate, a bile acid derivative, and cooperative effects with another differentiation inducer, cotylenin A. Leukemia Research, 32 (7), 1112-1123. 94. Tsai, W.H., Shih, C.H., Lin, C.C., Ho, C.K., Hsu, F.C. and Hsu, H.C. (2008), Monocyte chemotactic protein-1 in the migration of differentiated leukaemic cells toward alveolar epithelial cells. European Respiratory Journal, 31 (5), 957-962. 95. Moraes, C.A.D., Trompieri, N.M. and Cavalcante, F.H. (2008), Pediatric acute promyelocytic leukemia: All-transretinoic acid therapy in a Brazilian pediatric hospital. Journal of Pediatric Hematology Oncology, 30 (5), 387-390. 96. Hung, C.Y., Hsu, M.H., Huang, L.J., Hwang, C.S., Lee, O., Wu, C.Y., Chen, C.H. and Kuo, S.C. (2008), Synthesis of 1-substituted 3-pyridinylmethylidenylindolin-2-ones and 1-substituted 3-quinolinylmethylidenylindolin-2-ones as the enhancers of ATRA-induced differentiation in HL-60 cells. Bioorganic & Medicinal Chemistry, 16 (8), 4222-4232.
  7. 7. 7 97. Wang, L., Zhou, G.B., Liu, P., Song, J.H., Liang, Y., Yan, X.J., Xu, F., Wang, B.S., Mao, J.H., Shen, Z.X., Chen, S.J. and Chen, Z. (2008), Dissection of mechanisms of Chinese medicinal formula Realgar-Indigo naturalis as an effective treatment for promyelocytic leukemia. Proceedings of the National Academy of Sciences of the United States of America, 105 (12), 4826-4831. 98. Mantadakis, E., Samonis, G. and Kalmanti, M. (2008), A comprehensive review of acute promyelocytic leukemia in children. Acta Haematologica, 119 (2), 73-82. 99. Ohnishi, K. (2007), PML-RAR alpha inhibitors (ATRA, tamibaroten, arsenic troxide) for acute promyelocytic leukemia. International Journal of Clinical Oncology, 12 (5), 313-317. 100. Zhang, K., Guo, Q.L., You, Q.D., Yang, Y., Zhang, H.W., Yang, L., Gu, H.Y., Qi, Q., Tan, Z. and Wang, X.T. (2008), Wogonin induces the granulocytic differentiation of human NB4 promyelocytic leukemia cells and up-regulates phospholipid scramblase 1 gene expression. Cancer Science, 99 (4), 689-695. 101. Kannan-Thulasiraman, P., Dolniak, B., Kaur, S., Sassano, A., Kalvakolanu, D.V., Hay, N. and Platanias, L.C. (2008), Role of the translational repressor 4E-BP1 in the regulation of p21(Waf1/Cip1) expression by retinoids. Biochemical and Biophysical Research Communications, 368 (4), 983-989. 102. Wang, Z.Y. and Chen, Z. (2008), Acute promyelocytic leukemia: from highly fatal to highly curable. Blood, 111 (5), 2505-2515. 103. Jiang, G.S., Albihn, A., Tang, T.H., Tian, Z.G. and Henriksson, M. (2008), Role of Myc in differentiation and apoptosis in HL60 cells after exposure to arsenic trioxide or all-trans retinoic acid. Leukemia Research, 32 (2), 297-307. 104. Tefferi, A. (2008), The history of myeloproliferative disorders: before and after Dameshek. Leukemia, 22 (1), 3-13. 105. Tsiftsoglou, A.S. (2008), Multiple exploitable molecular targets for differentiation therapy of leukemias. Leukemia Research , 32 (1), 1-2. 106. Ishiguro, K. and Sartorelli, A.C. (2008), Relationship between the induction of leukemia cell differentiation and the enhancement of reporter gene expression in 3T3 Swiss cells. Leukemia Research, 32 (1), 89-96. 107. Delaune, A., Corbiere, C., Benjelloun, F.D., Legrand, E., Vannier, J.P., Ripoll, C. and Vasse, M. (2008), Promyelocytic leukemia-nuclear body formation is an early event leading to retinoic acid-induced differentiation of neuroblastoma cells. Journal of Neurochemistry, 104 (1), 89-99. 108. Horie, R. (2007), NF-kappa B in pathogenesis and treatment of adult T-cell leukemia/lymphoma. International Reviews of Immunology, 26 (5-6), 269-281. 109. Samochatova, E.V., Moschan, A.A., Aleinikova, O.V., Bespalova, A.V., Baidildina, D.D., Dubrovina, M.E., Fleishman, E.V., Nasedkina, T.V., Rumyantsev, S.A. and Rumyantsev, A.G. (2007), Long-term results of combined treatment of acute promyelocytic leukemia in children and adolescents with gene therapy. Terapevticheskii Arkhiv, 79 (7), 26-30. 110. Plevova, P., Bouchal, J., Fiuraskova, M., Papezova, M., Krepelova, A., Curik, R., Foretova, L., Navratilova, M., Zapletalova, J., Posolda, T. and Kolar, Z. (2007), PML and TRF2 protein expression in hereditary and sporadic colon cancer. Neoplasma, 54 (4), 269-277. 111. Huston, A. and Lyman, G.H. (2007), Agents under investigation for the treatment and prevention of neutropenia. Expert Opinion on Investigational Drugs, 16 (11), 1831-1840. 112. Mongan, N.P. and Gudas, L.J. (2007), Diverse actions of retinoid receptors in cancer prevention and treatment. Differentiation, 75 (9), 853-870. 113. King, M.E. and Rowe, J.M. (2007), Recent developments in acute myelogenous leukemia therapy. Oncologist, 12), 14-21. 114. Fields, A.L., Soprano, D.R. and Soprano, K.J. (2007), Retinoids in biological control and cancer. Journal of Cellular Biochemistry, 102 (4), 886-898. 115. Miwako, I. and Kagechika, H. (2007), Tamibarotene. Drugs of Today, 43 (8), 563-568.
  8. 8. 8 116. Dilda, P.J. and Hogg, P.J. (2007), Arsenical-based cancer drugs. Cancer Treatment Reviews, 33 (6), 542-564. 117. Honma, Y. and Akimoto, M. (2007), Therapeutic strategy using phenotypic modulation of cancer cells by differentiation-inducing agents. Cancer Science, 98 (11), 1643-1651. 118. Yu, Y., Wang, L.S., Shen, S.M., Xia, L., Zhang, L., Zhu, Y.S. and Chen, G.Q. (2007), Subcellular proteome analysis of camptothecin analogue NSC606985-treated acute myeloid leukemic cells. Journal of Proteome Research, 6 (9), 3808-3818. 119. Kharfan-Dabaja, M.A., bou Mourad, Y.R., Fernandez, H.F., Pasquini, M.C. and Santos, E.S. (2007), Hematopoietic cell transplantation in acute promyelocytic leukemia: A comprehensive review. Biology of Blood and Marrow Transplantation, 13 (9), 997-1004. 120. Panda, N., Banerjee, S., Mandal, N.B. and Sahu, N.P. (2006), Pregnane glycosides. Natural Product Communications, 1 (8), 665-695. 121. Chen, G.Q., Wang, L.S., Wu, Y.L. and Yu, Y. (2007), Leukemia, an effective model for chemical biology and target therapy. Acta Pharmacologica Sinica, 28 (9), 1316-1324. 122. Zhou, G.B., Li, G., Chen, J. and Chen, Z. (2007), From dissection of disease pathogenesis to elucidation of mechanisms of targeted therapies: leukemia research in the genomic era. Acta Pharmacologica Sinica, 28 (9), 1434-1449. 123. Li, Y., Yin, W., Wang, X., Zhu, W.B., Huang, Y.J. and Yan, G.M. (2007), Cholera toxin induces malignant glioma cell differentiation via the PKA/CREB pathway. Proceedings of the National Academy of Sciences of the United States of America, 104 (33), 13438-13443. 124. Karagianni, P. and Wong, J. (2007), HDAC3: taking the SMRT-N-CoRrect road to repression. Oncogene, 26 (37), 5439-5449. 125. Kim, D.G., Jeong, Y.I. and Nah, J.W. (2007), All-trans retinoic acid release from polyion-complex micelles of methoxy poly(ethylene glycol) grafted chitosan. Journal of Applied Polymer Science, 105 (6), 3246-3254. 126. Jimi, S., Mashima, K., Matsumoto, T., Hara, S., Suzumiya, J. and Tamura, K. (2007), RAR alpha is a regulatory factor for Am-80-induced cell growth inhibition of hematologic malignant cells. International Journal of Oncology, 31 (2), 397-404. 127. Asou, N., Kishimoto, Y., Kiyoi, H., Okada, M., Kawai, Y., Tsuzuki, M., Horikawa, K., Matsuda, M., Shinagawa, K., Kobayashi, T., Ohtake, S., Nishimura, M., Takahashi, M., Yagasaki, F., Takeshita, A., Kimura, Y., Lwanaga, M., Naoe, T. and Ohno, R. (2007), A randomized study with or without intensified maintenance chemotherapy in patients with acute promyelocytic leukemia who have become negative for PML-RAR alpha transcript after consolidation therapy: The Japan Adult Leukemia Study Group (JALSG) APL97 study. Blood, 110 (1), 59-66. 128. Zhou, G.B., Zhang, J., Wang, Z.Y., Chen, S.J. and Chen, Z. (2007), Treatment of acute promyelocytic leukaemia with all-trans retinoic acid and arsenic trioxide: a paradigm of synergistic molecular targeting therapy. Philosophical Transactions of the Royal Society B-Biological Sciences, 362 (1482), 959-971. 129. Garattini, E., Gianni, M. and Terao, M. (2007), Retinoids as differentiating agents in oncology: A network of interactions with intracellular pathways as the basis for rational therapeutic combinations. Current Pharmaceutical Design, 13 (13), 1375-1400. 130. Edsjo, A., Holmquist, L. and Pahlman, S. (2007), Neuroblastoma as an experimental model for neuronal differentiation and hypoxia-induced tumor cell dedifferentiation. Seminars in Cancer Biology, 17 (3), 248-256. 131. Sastre, A., Gago, E., Banos, M. and Gomez, E. (2007), Acute renal failure in the transretinoic syndrome. Nefrologia, 27 (2), 184-190. 132. Schuler, A.D., Si, J.T., Mueller, L., Simon, J.A. and Collins, S.J. (2007), KN-62 analogues as potent differentiating agents of HL-60 cells. Leukemia Research, 31 (5), 683-689. 133. Zhou, G.B., Chen, S.J., Wang, Z.Y. and Chen, Z. (2007), Back to the future of oridonin: again, compound from medicinal herb shows potent antileukernia efficacies in vitro and in vivo. Cell Research, 17 (4), 274-276.
  9. 9. 9 134. Si, J.T., Mueller, L. and Collins, S.J. (2007), CaMKII regulates retinoic acid receptor transcriptional activity and the differentiation of myeloid leukemia cells. Journal of Clinical Investigation, 117 (5), 1412-1421. 135. Suzuki, R., Rao, P. and Sasaguri, S. (2007), Current status and future of target-based therapeutics. Current Cancer Drug Targets, 7 (3), 273-284. 136. Hu, J., Zhou, G.B., Wang, Z.Y., Chen, S.J. and Chen, Z. (2007), Mutant transcription factors and tyrosine kinases as therapeutic targets for leukemias: From acute promyelocytic leukemia to chronic myeloid leukemia and beyond. Advances in Cancer Research, Vol 98, 98), 191-220. 137. Nishikiori, N., Osanai, M., Chiba, H., Kojima, T., Ohguro, H. and Sawada, N. (2007), Inhibitory effects of retinoic acid receptor alpha stimulants on murine cataractogenesis through suppression of deregulated calpains. Investigative Ophthalmology & Visual Science, 48 (5), 2224-2229. 138. Garattini, E., Gianni, M. and Terao, M. (2007), Cytodifferentiation by retinoids, a novel therapeutic option in oncology: Rational combinations with other therapeutic agents. Vitamin A, 75), 301-354. 139. Zhou, G.B., Kang, H., Wang, L., Gao, L., Liu, P., Xie, J., Zhang, F.X., Weng, X.Q., Shen, Z.X., Chen, J., Gu, L.J., Yan, M., Zhang, D.E., Chen, S.J., Wang, Z.Y. and Chen, Z. (2007), Oridonin, a diterpenoid extracted from medicinal herbs, targets AML1-ETO fusion protein and shows potent antitumor activity with low adverse effects on t(8;21) leukemia in vitro and in vivo. Blood, 109 (8), 3441-3450. 140. Rossi, E., Picozzi, P., Bodega, B., Lavazza, C., Carlo-Stella, C., Marozzi, A. and Ginelli, E. (2007), Forced expression of RDH10 gene retards growth of HepG2 cells. Cancer Biology & Therapy, 6 (2), 238-245. 141. Aribi, A., Kantarjian, H.M., Estey, E.H., Koller, C.A., Thomas, D.A., Kornblau, S.M., Faderl, S.H., Laddie, N.M., Garcia-Manero, G. and Cortes, J.E. (2007), Combination therapy with arsenic trioxide, all-trans retinoic acid, and gemtuzumab ozogamicin in recurrent acute promyelocytic leukemia. Cancer, 109 (7), 1355-1359. 142. Zhang, Y.F., Jia, S.Q., Liu, Y., Li, B., Wang, Z.H., Lu, H. and Zhu, C.M. (2007), A clinical study of all-trans-retinoid-induced differentiation therapy of advanced thyroid cancer. Nuclear Medicine Communications, 28 (4), 251-255. 143. Gao, Y., Camacho, L.H. and Mehta, K. (2007), Retinoic acid-induced CD38 antigen promotes leukemia cells attachment and interferon-gamma/interleukin-1 beta-dependent apoptosis of endothelial cells: Implications in the etiology of retinoic acid syndrome. Leukemia Research, 31 (4), 455-463. 144. Rowe, J.M. (2007), The true impact of new targeted therapies for AML. Best Practice & Research Clinical Haematology, 20 (1), 1-4. 145. Herbert, K.E., Walkley, C.R., Winkler, I.G., Hendy, J., Olsen, G.H., Yuan, Y.D., Chandraratna, R.A.S., Prince, H.M., Levesque, J.P. and Purton, L.E. (2007), Granulocyte colony-stimulating factor and an RARa specific agonist, VTP195183, synergize to enhance the mobilization of hematopoietic progenitor cells. Transplantation, 83 (4), 375-384. 146. Fenaux, P., Wang, Z.Z. and Degos, L. (2007), Treatment of acute promyelocytic leukemia by retinoids. ), 101-128. 147. Maslak, P.G., Jurcic, J.G. and Scheinberg, D.A. (2007), Monoclonal antibody therapy of APL. ), 205-219. 148. Jing, Y. and Waxman, S. (2007), The design of selective and non-selective combination therapy for acute promyelocytic leukemia. Acute Promyelocytic Leukemia: Molecular Genetics, Mouse Models and Targeted Therapy, 313), 245-269. 149. Tsai, W.H., Hsu, H.C., Lin, C.C., Ho, C.K. and Kou, Y.R. (2007), Role of inteyleukin-8 and growth-regulated oncogene-alpha in the chemotactic migration of all-trans retinoic acid-treated promyelocytic leukemic cells toward alveolar epithelial cells. Critical Care Medicine, 35 (3), 879-885.
  10. 10. 10 150. Ohnuma-Ishikawa, K., Morio, T., Yamada, T., Sugawara, Y., Ono, M., Nagasawa, M., Yasuda, A., Morimoto, C., Ohnuma, K., Dang, N.H., Hosoi, H., Verdin, E. and Mizutani, S. (2007), Knockdown of XAB2 enhances all-trans retinoic acid-induced cellular differentiation in all-trans retinoic acid-sensitive and -resistant cancer cells. Cancer Research, 67 (3), 1019-1029. 151. Taschner, S., Koesters, C., Platzer, B., Jorgl, A., Ellmeier, W., Benesch, T. and Strobl, H. (2007), Down-regulation of RXR alpha expression is essential for neutrophil development from granulocyte/monocyte progenitors. Blood, 109 (3), 971-979. 152. Brandts, C.H., Berdel, W.E. and Serve, H. (2007), Oncogenic signaling in acute myeloid leukemia. Current Drug Targets, 8 (2), 237-246. 153. Kleger, A., Busch, T., Liebau, S., Prelle, K., Paschke, S., Beil, M., Rolletschek, A., Wobus, A., Wolf, E., Adler, G. and Seufferlein, T. (2007), The bioactive lipid sphingosylphosphorylcholine induces differentiation of mouse embryonic stem cells and human promyelocytic leukaemia cells. Cellular Signalling, 19 (2), 367-377. 154. Yang, G., Thompson, M.A., Brandt, S.J. and Hiebert, S.W. (2007), Histone deacetylase inhibitors induce the degradation of the t(8;21) fusion oncoprotein. Oncogene, 26 (1), 91-101. 155. Shimizu, T., Esaki, L., Mizuno, H. and Takeda, K. (2006), Granulocyte macrophage colony-stimulating factor enhances retinoic acid-induced gene expression. Journal of Leukocyte Biology, 80 (4), 889-896. 156. Ades, L., Chevret, S., Raffoux, E., de Botton, S., Guerci, A., Pigneux, A., Stoppa, A.M., Lamy, T., Rigal-Huguet, F., Vekhoff, A., Meyer-Monard, S., Maloisel, F., Deconinck, E., Ferrant, A., Thomas, X., Fegueux, N., Chomienne, C., Dombret, H., Degos, L. and Fenaux, P. (2006), Is cytarabine useful in the treatment of acute promyelocytic leukemia? Results of a randomized trial from the European Acute Promyelocytic Leukemia Group. Journal of Clinical Oncology, 24 (36), 5703-5710. 157. Tabata, C., Kadokawa, Y., Tabata, R., Takahashi, M., Okoshi, K., Sakai, Y., Mishima, M. and Kubo, H. (2006), All-trans-retinoic acid prevents radiation- or bleomycin-induced pulmonary fibrosis. American Journal of Respiratory and Critical Care Medicine, 174 (12), 1352-1360. 158. Wu, N., Zhang, W., Yang, Y., Liang, Y.L., Wang, L.Y., Jin, J.W., Cai, X.M. and Zha, X.L. (2006), Profilin 1 obtained by proteomic analysis in all-trans retinoic acid-treated hepatocarcinorna cell lines is involved in inhibition of cell proliferation and migration. Proteomics, 6 (22), 6095-6106. 159. Tsimberidou, A.M., Kantarjian, H., Keating, M.J. and Estey, E. (2006), Optimizing treatment for elderly patients with acute promyelocytic leukemia: is it time to replace chemotherapy with all-trans retinoic acid and arsenic trioxide? Leukemia & Lymphoma, 47 (11), 2282-2288. 160. Schulenburg, A., Ulrich-Pur, H., Thurnher, D., Erovic, B., Florian, S., Sperr, W.R., Kalhs, P., Marian, B., Wrba, F., Zielinski, C.C. and Valent, P. (2006), Neoplastic stem cells: A novel therapeutic target in clinical oncology. Cancer, 107 (10), 2512-2520. 161. Jeong, Y.I., Kim, S.H., Jung, T.Y., Kim, I.Y., Kang, S.S., Jin, Y.H., Ryu, H.H., Sun, H.S., Jin, S.G., Kim, K.K., Ahn, K.Y. and Jung, S. (2006), Polyion complex micelles composed of all-trans retinoic acid and poly (ethylene glycol)-grafted-citosan. Journal of Pharmaceutical Sciences , 95 (11), 2348-2360. 162. Milligan, D.W., Grimwade, D., Cullis, J.O., Bond, L., Swirsky, D., Craddock, C., Kell, J., Homewood, J., Campbell, K., McGinley, S., Wheatley, K. and Jackson, G. (2006), Guidelines on the management of acute myeloid leukaemia in adults. British Journal of Haematology, 135 (4), 450-474. 163. Lee, Y.J., Jones, L.C., Timchenko, N.A., Perrotti, D., Tenen, D.G. and Kogan, S.C. (2006), CCAAT/enhancer binding proteins alpha and epsilon cooperate with all-trans retinoic acid in therapy but differ in their antileukernic activities. Blood, 108 (7), 2416-2419. 164. Zhang, Y.M. and Rowley, J.D. (2006), Chromatin structural elements and chromosomal translocations in leukemia. Dna Repair, 5 (9-10), 1282-1297.
  11. 11. 11 165. Kizaki, M., Xian, M.J., Sagawa, M. and Ikeda, Y. (2006), Induction of apoptosis via the modulation of reactive oxygen species (ROS) production in the treatment of myeloid leukemia. Current Pharmaceutical Biotechnology, 7 (5), 323-329. 166. Glienke, W., Chow, K.U., Bauer, N. and Bergmann, L. (2006), Down-regulation of wt1 expression in leukemia cell lines as part of apoptotic effect in arsenic treatment using two compounds. Leukemia & Lymphoma, 47 (8), 1629-1638. 167. Balajthy, Z., Csomos, K., Vamosi, G., Szanto, A., Lanotte, M. and Fesus, L. (2006), Tissue-transglutaminase contributes to neutrophil granulocyte differentiation and functions. Blood, 108 (6), 2045-2054. 168. Ko, J., Yun, C.Y., Lee, J.S., Kim, D.H., Yuk, J.E. and Kim, I.S. (2006), Differential regulation of CC chemokine receptors by 9-cis retinoic acid in the human mast cell line, HMC-1. Life Sciences, 79 (13), 1293-1300. 169. Horie, R., Watanabe, T. and Umezawa, K. (2006), Blocking NF-kappa B as a potential strategy to treat adult T-cell leukemia/lymphoma. Drug News & Perspectives, 19 (4), 201-209. 170. Gu, M.Y., Wang, Z.W., Yu, H.X. and Li, G.Z. (2006), Microemulsion of Tween-80/n-butylalcohol/H2O system and its entrapment efficiency of ATRA. Journal of Dispersion Science and Technology, 27 (7), 949-954. 171. Sjoholt, G., Bedringaas, S.L., Doskeland, A.P. and Gjertsen, B.T. (2006), Proteomic strategies for individualizing therapy of acute myeloid leukemia (AML). Current Pharmaceutical Biotechnology, 7 (3), 159-170. 172. Liu, Y.F., Zhu, Y.M., Shen, S.H., Shen, Z.X., Li, J.M., Chen, S.J., Chen, Z. and Jiong, H.U. (2006), Molecular response in acute promyelocytic leukemia: a direct comparison of regular and real-time RT-PCR. Leukemia, 20 (8), 1393-1399. 173. Rush, E.A., Schlesinger, K.W., Watkins, S.C. and Redner, R.L. (2006), The NPM-RAR fusion protein associated with the t(5;17) variant of APL does not interact with PML. Leukemia Research, 30 (8), 979-986. 174. Tsimberidou, A.M., Tirado-Gomez, M., Andreeff, M., O'Brien, S., Kantarjian, H., Keating, M., Lopez-Berestein, G. and Estey, E. (2006), Single-agent liposomal all-trans retinoic acid can cure some patients with untreated acute promyelocytic leukemia: an update of The University of Texas M. D. Anderson Cancer Center Series. Leukemia & Lymphoma, 47 (6), 1062-1068. 175. Chim, C.S. and Kwong, Y.L. (2006), Adverse prognostic impact of CDKN2B hyper-methylation in acute promyelocytic leukemia. Leukemia & Lymphoma, 47 (5), 815-825. 176. Jiang, G.S., Bi, K.H., Tang, T.H., Wang, J.W., Zhang, Y.K., Zhang, W., Ren, H.Q., Bai, H.Q. and Wang, Y.S. (2006), Down-regulation of TRRAP-dependent hTERT and TRRAP-independent CAD activation by Myc/Max contributes to the differentiation of HL60 cells after exposure to DMSO. International Immunopharmacology, 6 (7), 1204-1213. 177. Eifert, C., Sangster-Guity, N., Yu, L.M., Chittur, S.V., Perez, A.V., Tine, J.A. and McCormick, P.J. (2006), Global gene expression profiles associated with retinoic acid-induced differentiation of embryonal carcinoma cells. Molecular Reproduction and Development, 73 (7), 796-824. 178. Qi, H.L. and Ratnam, M. (2006), Synergistic induction of folate receptor beta by all-trans retinoic acid and histone deacetylase inhibitors in acute myelogenous leukemia cells: Mechanism and utility in enhancing selective growth inhibition by antifolates. Cancer Research, 66 (11), 5875-5882. 179. Xia, L., Wurmbach, E., Waxman, S. and Jing, Y. (2006), Upregulation of Bfl-1/A1 in leukemia cells undergoing differentiation by all-trans retinoic acid treatment attenuates chemotherapeutic agent-induced apoptosis. Leukemia, 20 (6), 1009-1016. 180. Purton, L.E., Dworkin, S., Olsen, G.H., Walkley, C.R., Fabb, S.A., Collins, S.J. and Chambon, P. (2006), RAR gamma is critical for maintaining a balance between hematopoietic stem cell self-renewal and differentiation. Journal of Experimental Medicine, 203 (5), 1283-1293.
  12. 12. 12 181. Kizaki, M. (2006), New therapeutic approach for myeloid leukemia: Induction of apoptosis via modulation of reactive oxygen species production by natural compounds. International Journal of Hematology, 83 (4), 283-288. 182. Nozaki, Y., Yamagata, T., Sugiyam, M., Ikoma, S., Kinoshita, K. and Funauchi, M. (2006), Anti-inflammatory effect of all-trans-retinoic acid in inflammatory arthritis. Clinical Immunology, 119 (3), 272-279. 183. Pendino, F., Hillion, J., Dudognon, C., Delaunay, J., Mourah, S., Podgorniak, M.P., Lafon, I., Chomienne, C., Lanotte, M., Dombret, H., Rousselot, P. and Segal-Bendirdjian, E. (2006), Telomerase targeting by retinoids in cells from patients with myeloid leukemias of various subtypes, not only APL. Leukemia, 20 (4), 599-603. 184. Horie, R., Watanabe, M., Okamura, T., Taira, M., Shoda, M., Motoji, T., Utsunomiya, A., Watanabe, T., Higashihara, M. and Umezawa, K. (2006), DHMEQ, a new NF-kappa B inhibitor, induces apoptosis and enhances fludarabine effects on chronic lymphocytic leukemia cells. Leukemia, 20 (5), 800-806. 185. Yasugi, E., Horiuchi, A., Uemura, I., Okuma, E., Nakatsu, M., Saeki, K., Kamisaka, Y., Kagechika, H., Yasuda, K. and Yuo, A. (2006), Peroxisome proliferator-activated receptor gamma ligands stimulate myeloid differentiation and lipogenensis in human leukemia NB4 cells. Development Growth & Differentiation, 48 (3), 177-188. 186. Kim, D.G., Choi, C.Y., Jeong, Y.I., Jang, M.K., Nah, J.W., Kang, S.K. and Bang, M.S. (2006), All-trans retinoic acid-associated low molecular weight water-soluble chitosan nanoparticles based on ion complex. Macromolecular Research, 14 (1), 66-72. 187. Kawakami, S., Suzuki, S., Yamashita, F. and Hashida, M. (2006), Induction of apoptosis in A549 human lung cancer cells by all-trans retinoic acid incorporated in DOTAP/cholesterol liposomes. Journal of Controlled Release, 110 (3), 514-521. 188. Inche, A.G. and La Thangue, N.B. (2006), Keynote review: Chromation control and cancer-drug discovery: realizing the promise. Drug Discovery Today, 11 (3-4), 97-109. 189. Huynh, C.K., Brodie, A.M.H. and Njar, V.C.O. (2006), Inhibitory effects of retinoic acid metabolism blocking agents (RAMBAs) on the growth of human prostate cancer cells and LNCaP prostate tumour xenografts in SCID mice. British Journal of Cancer, 94 (4), 513-523. 190. Cirpanli, Y., Unlu, N., Calis, S. and Hincal, A.A. (2005), Formulation and in-vitro characterization of retinoic acid loaded poly (lactic-co-glycolic acid) microspheres. Journal of Microencapsulation, 22 (8), 877-889. 191. Liu, W., Guo, M., Xu, Y.B., Li, D., Zhou, Z.N., Wu, Y.L., Chen, Z., Kogan, S.C. and Chen, G.Q. (2006), Induction of tumor arrest and differentiation with prolonged survival by intermittent hypoxia in a mouse model of acute myeloid leukemia. Blood, 107 (2), 698-707. 192. Kawamata, H., Tachibana, M., Fujimori, T. and Imai, Y. (2006), Differentiation-inducing therapy for solid tumors. Current Pharmaceutical Design, 12 (3), 379-385. 193. Ghavamzadeh, A., Alimoghaddam, K., Ghaffari, S.H., Rostami, S., Jahani, M., Hosseini, R., Mossavi, A., Baybordi, E., Khodabadeh, A., Iravani, M., Bahar, B., Mortazavi, Y., Totonchi, M. and Aghdami, N. (2006), Treatment of acute promyelocytic leukemia with arsenic trioxide without ATRA and/or chemotherapy. Annals of Oncology, 17 (1), 131-134. 194. Haga, N., Fujita, N. and Tsuruo, T. (2005), Involvement of mitochondrial aggregation in arsenic trioxide (As2O3)-induced apoptosis in human glioblastoma cells. Cancer Science, 96 (11), 825-833. 195. Hicsonmez, G. (2006), The effect of steroid on myeloid leukemic cells: The potential of short-course high-dose methylprednisolone treatment in inducing differentiation, apoptosis and in stimulating myelopoiesis. Leukemia Research, 30 (1), 60-68. 196. Yan, H., Peng, Z.G., Wu, Y.L., Jiang, Y., Yu, Y., Huang, Y., Zhu, Y.S., Zhao, Q. and Chen, G.Q. (2005), Hypoxia-simulating agents and selective stimulation of arsenic trioxide-induced growth arrest and cell differentiation in acute promyelocytic leukemic cells. Haematologica-the Hematology Journal, 90 (12), 1607-1616.
  13. 13. 13 197. Wang, Y.A., Shen, K., Ishida, Y., Wang, Y.L., Kakizuka, A. and Brooks, S.C. (2005), Induction of murine leukemia and lymphoma by dominant negative retinoic acid receptor alpha. Molecular Carcinogenesis, 44 (4), 252-261. 198. Kawakami, S., Opanasopit, P., Yokoyama, M., Chansri, N., Yamamoto, T., Okano, T., Yamashita, F. and Hashida, M. (2005), Biodistribution characteristics of all-trans retinoic acid incorporated in liposomes and polymeric micelles following intravenous administration. Journal of Pharmaceutical Sciences, 94 (12), 2606-2615. 199. Lengfelder, E., Saussele, S., Weisser, A., Buchner, T. and Hehlmann, R. (2005), Treatment concepts of acute promyelocytic leukemia. Critical Reviews in Oncology Hematology, 56 (2), 261-274. 200. Kubo, Y., Wada, M., Ohba, T. and Takahashi, N. (2005), Formation of retinoylated proteins from retinoyl-CoA in rat tissues. Journal of Biochemistry, 138 (4), 493-500. 201. Chan, K.H., Yuen, S.L.S. and Joshua, D. (2005), A case of all-trans retinoic acid-induced myositis in the treatment of acute promyelocytic leukaemia. Clinical and Laboratory Haematology, 27 (6), 399-401. 202. Mathieu, J., Giraudier, S., Lanotte, M. and Besancon, F. (2005), Retinoid-induced activation of NF-kappa B in APL cells is not essential for granulocytic differentiation, but prolongs the life span of mature cells. Oncogene, 24 (48), 7145-7155. 203. Shigeno, K., Naito, K., Sahara, N., Kobayashi, M., Nakamura, S., Fujisawa, S., Shinjo, K., Takeshita, A., Ohno, R. and Ohnishi, K. (2005), Arsenic trioxide therapy in relapsed or refractory Japanese patients with acute promyelocytic leukemia: Updated outcomes of the phase II study and postremission therapies. International Journal of Hematology, 82 (3), 224-229. 204. Zheng, R. and Small, D. (2005), Mutant FLT3 signaling contributes to a block in myeloid differentiation. Leukemia & Lymphoma , 46 (12), 1679-1687. 205. Zhou, G.B., Chen, S.J. and Chen, Z. (2005), Acute promyclocytic leukemia: A model of molecular target based therapy. Hematology, 10), 270-280. 206. Dao, C.T. and Zhang, D.E. (2005), ISG15: A ubiquitin-like enigma. Frontiers in Bioscience, 10), 2701-2722. 207. Evans, T. (2005), Regulation of hematopoiesis by retinoid signaling. Experimental Hematology, 33 (9), 1055-1061. 208. Mann, K.K., Padovani, A.M.S., Guo, Q., Colosimo, A.L., Lee, H.Y., Kurie, J.M. and Miller, W.H. (2005), Arsenic trioxide inhibits nuclear receptor function via SEK1/JNK-mediated RXR alpha phosphorylation. Journal of Clinical Investigation, 115 (10), 2924-2933. 209. Sharma, R.A. and Browning, M.J. (2005), Mechanisms of the self/non-self-survey in the defense against cancer: Potential for chemoprevention? Critical Reviews in Oncology Hematology, 56 (1), 5-22. 210. Wang, Q., Harrison, J.S., Uskokovic, M., Kutner, A. and Studzinski, G.P. (2005), Translational study of vitamin D differentiation therapy of myeloid leukemia: effects of the combination with a p38 MAPK inhibitor and an antioxidant. Leukemia, 19 (10), 1812-1817. 211. Kagechika, H. and Shudo, K. (2005), Synthetic retinoids: Recent developments concerning structure and clinical utility. Journal of Medicinal Chemistry, 48 (19), 5875-5883. 212. Shinjo, K., Takeshita, A., Sahara, N., Kobayashi, M., Nakamura, S., Shigeno, K., Naito, K., Maekawa, M., Ohnishi, K. and Ohno, R. (2005), Delayed recovery of normal hematopoiesis in arsenic trioxide treatment of acute promyelocytic leukemia: A comparison to all-trans retinoic acid treatment. Internal Medicine, 44 (8), 818-824. 213. Jing, Y.K., Hellinger, N., Xia, L.J., Monks, A., Sausville, E.A., Zelent, A. and Waxman, S. (2005), Benzodithiophenes induce differentiation and apoptosis in human leukemia cells. Cancer Research, 65 (17), 7847-7855. 214. Xu, K., Guidez, F., Glasow, A., Chung, D., Petrie, K., Stegmaier, K., Wang, K.K., Zhang, J., Jing, Y., Zelent, A. and Waxman, S. (2005), Benzodithiophenes potentiate differentiation of acute promyelocytic leukemia cells by lowering the threshold for ligand-mediated
  14. 14. 14 corepressor/coactivator exchange with retinoic acid receptor alpha and enhancing changes in all-trans-retinoic acid-regulated gene expression. Cancer Research, 65 (17), 7856-7865. 215. Wang, Q., Salman, H., Danilenko, M. and Studzinski, G.P. (2005), Cooperation between antioxidants and 1,25-dihydroxyvitamin D-3 in induction of leukemia HL60 cell differentiation through the JNK/AP-1/Egr-1 pathway. Journal of Cellular Physiology, 204 (3), 962-972. 216. Takahashi, N. and Ohba, T. (2005), Regulation of cytodifferentiation by retinoylation. Seikagaku, 77 (6), 527-536. 217. Gehrmann, M., Schonberger, J., Zilch, T., Rossbacher, L., Thonigs, G., Eilles, C. and Multhoff, G. (2005), Retinoid- and sodium-butyrate-induced decrease in heat shock protein 70 membrane-positive tumor cells is associated with reduced sensitivity to natural killer cell lysis, growth delay, and altered growth morphology. Cell Stress & Chaperones, 10 (2), 136-146. 218. Dally, N., Hoffman, R., Haddad, N., Sarig, G., Rowe, J.M. and Brenner, B. (2005), Predictive factors of bleeding and thrombosis during induction therapy in acute promyelocytic leukemia - a single center experience in 34 patients. Thrombosis Research, 116 (2), 109-114. 219. Lu, M., Lopez, R., Nakajo, S., Nakaya, K. and Jing, Y.K. (2005), Expression of estrogen receptor alpha, retinoic acid receptor alpha and cellular retinoic acid binding protein II genes is coordinately regulated in human breast cancer cells. Oncogene, 24 (27), 4362-4369. 220. Xue, Z.H., Jiang, Y., Yu, Y., Wang, L.S., Chen, G.Q. and Zhao, Q. (2005), Metavanadate suppresses desferrioxamine-induced leukemic cell differentiation with reduced hypoxia-inducible factor-1 alpha protein. Biochemical and Biophysical Research Communications, 332 (4), 1140-1145. 221. Liu, M.J., Wang, Z., Sun, S.Q. and Wu, Q.Y. (2005), Monitoring all-trans-retinoic acid-induced differentiation of HL-60 cells by Fourier-transform infrared spectroscopy. Spectroscopy and Spectral Analysis , 25 (5), 688-692. 222. Zheng, P.Z., Wang, K.K., Zhang, Q.Y., Huang, Q.H., Du, Y.Z., Zhang, Q.H., Xiao, D.K., Shen, S.H., Imbeaud, S., Eveno, E., Zhao, C.J., Chen, Y.L., Fan, H.Y., Waxman, S., Auffray, C., Jin, G., Chen, S.J., Chen, Z. and Zhang, J. (2005), Systems analysis of transcriptome and proteome in retinoic acid/arsenic trioxide-induced cell differentiation/apoptosis of promyelocytic leukemia. Proceedings of the National Academy of Sciences of the United States of America, 102 (21), 7653-7658. 223. Schlenk, R.F., Germing, U., Hartmann, F., Glasmacher, A., Fischer, J.T., Fuentes, F.D.Y., Gotze, K., Pralle, H., Nerl, C., Salwender, H., Grimminger, W., Petzer, A., Hensel, M., Benner, A., Zick, L., Dohner, K., Frohling, S. and Dohner, H. (2005), High-dose cytarabine and mitoxantrone in consolidation therapy for acute promyelocytic leukemia. Leukemia, 19 (6), 978-983. 224. Meani, N., Minardi, S., Licciulli, S., Gelmetti, V., Lo Coco, F., Nervi, C., Pelicci, P.G., Muller, H. and Alcalay, M. (2005), Molecular signature of retinoic acid treatment in acute promyelocytic leukemia. Oncogene, 24 (20), 3358-3368. 225. Scolnik, M.P., Aranguren, P.N., Cuello, M.T., Palacios, M.F., Sanjurjo, J., Giunta, M., Bracco, M.M.E. and Acevedo, S. (2005), Biphenotypic acute leukemia with t(15;17). Leukemia & Lymphoma, 46 (4), 607-610. 226. Osanai, M. and Petkovich, M. (2005), Expression of the retinoic acid-metabolizing enzyme CYP26A1 limits programmed cell death. Molecular Pharmacology, 67 (5), 1808-1817. 227. Ishibe, T., Nakayama, T., Okamoto, T., Aoyama, T., Nishijo, K., Shibata, K.R., Shima, Y., Nagayama, S., Katagiri, T., Nakamura, Y., Nakamura, T. and Toguchida, J. (2005), Disruption of fibroblast growth factor signal pathway inhibits the growth of synovial sarcomas: Potential application of signal inhibitors to molecular target therapy. Clinical Cancer Research, 11 (7), 2702-2712. 228. Debier, C. and Larondelle, Y. (2005), Vitamins A and E: metabolism, roles and transfer to offspring. British Journal of Nutrition, 93 (2), 153-174.
  15. 15. 15 229. Kumagai, T., Shih, L.Y., Hughes, S.V., Desmond, J.C., O'Kelly, J., Hewison, M. and Koeffler, H.P. (2005), 19-Nor-1,25(OH)(2)D-2 (a novel, noncalcemic vitamin D analogue), combined with arsenic trioxide, has potent antitumor activity against myeloid leukemia. Cancer Research, 65 (6), 2488-2497. 230. Zhou, G.B., Zhao, W.L., Wang, Z.Y., Chen, S.J. and Chen, Z. (2005), Retinoic acid and arsenic for treating acute promyelocytic leukemia. Plos Medicine, 2 (1), 33-38. 231. Matsui, W., Smith, B.D., Vala, M., Beal, N., Huff, C.A., Diehl, L.F. and Jones, R.J. (2005), Requirement for myeloid growth factors in the differentiation of acute promyelocytic leukaemia. British Journal of Haematology, 128 (6), 853-862. 232. Sellers, W.R. and Meyerson, M. (2005), EGFR gene mutations: A call for global x global views of cancer. Journal of the National Cancer Institute, 97 (5), 326-328. 233. Laurenzana, A., Cellai, C., Vannucchi, A.M., Pancrazzi, A., Romanelli, M.N. and Paoletti, F. (2005), WEB-2086 and WEB-2170 trigger apoptosis in both ATRA-sensitive and -resistant promyelocytic leukemia cells and greatly enhance ATRA differentiation potential. Leukemia, 19 (3), 390-395. 234. Heuze, M.L., Guibal, F.C., Banks, C.A., Conaway, J.W., Conaway, R.C., Cayre, Y.E., Benecke, A. and Lutz, P.G. (2005), ASB2 is an elongin BC-interacting protein that can assemble with cullin 5 and Rbx1 to reconstitute an E3 ubiquitin ligase complex. Journal of Biological Chemistry, 280 (7), 5468-5474. 235. Rosmarin, A.G., Yang, Z.F. and Resendes, K.K. (2005), Transcriptional regulation in myelopoiesis: Hematopoietic fate choice, myeloid differentiation, and leukemogenesis. Experimental Hematology, 33 (2), 131-143. 236. Toma, S., Emionite, L., Scaramuccia, A., Ravera, G. and Scarabelli, L. (2005), Retinoids and human breast cancer: in vivo effects of an antagonist for RAR-alpha. Cancer Letters, 219 (1), 27-31. 237. Lal, L., Li, Y.Z., Smith, J., Sassano, A., Uddin, S., Parmar, S., Tallman, M.S., Minucci, S., Hay, N. and Platanias, L.C. (2005), Activation of the p70 S6 kinase by all-trans-retinoic acid in acute promyelocytic leukemia cells. Blood, 105 (4), 1669-1677. 238. Hu, J., Fang, J., Dong, Y., Chen, S.J. and Chen, Z. (2005), Arsenic in cancer therapy. Anti-Cancer Drugs, 16 (2), 119-127. 239. Arsenou, E.S., Papadimitriou, E.P., Kliafa, E., Hountala, M. and Nikolaropoulos, S.S. (2005), Effects of retinoic acid steroidal analogs on human leukemic HL60 cell proliferation in vitro and on angiogenesis in vivo. Anti-Cancer Drugs, 16 (2), 151-158. 240. Watanabe, M., Dewan, Z., Okamura, T., Sasaki, M., Itoh, K., Higashihara, M., Mizoguchi, H., Honda, M., Sata, T., Watanabe, T., Yamamoto, N., Umezawa, K. and Horie, R. (2005), A novel NF-kappa B inhibitor DHMEQ selectively targets constitutive NF-kappa B activity and induces apoptosis of multiple myeloma cells in vitro and in vivo. International Journal of Cancer , 114 (1), 32-38. 241. Gando, S., Wada, H., Asakura, H., Iba, T., Eguchi, Y., Okamoto, K., Ohtomo, Y., Kawasugi, K., Koga, S., Koseki, A., Tsuji, H., Mayumi, T., Murata, A. and Nakagawa, M. (2005), Evaluation of new Japanese diagnostic criteria for disseminated intravascular coagulation in critically ill patients. Clinical and Applied Thrombosis-Hemostasis, 11 (1), 71-76. 242. Michael, M. and Doherty, M.M. (2005), Tumoral drug metabolism: Overview and its implications for cancer therapy. Journal of Clinical Oncology, 23 (1), 205-229. 243. Dutcher, J.P., Lee, S., Gallagher, R.E., Makary, A.Z., Hines, J.D., Londer, H., Farnen, J.P., Bennett, J.M., Paietta, E., Rowe, J.M., Goloubeva, O. and Wiernik, P.H. (2004), Phase II study of all-trans retinoic acid in the accelerated phase or early blastic phase of chronic myeloid leukemia: A study of the Eastern Cooperative Oncology Group (E1993). Leukemia & Lymphoma, 46 (3), 377-385. 244. Cosenza, M., Civallero, M., Sacchi, S., Marcheselli, R. and Pozzi, S. (2005), Biological effects of Atra and Arsenic Trioxide on short term cultures of non-M3 leukemic blasts. Leukemia & Lymphoma, 46 (2), 257-263.
  16. 16. 16 245. Hu, L.D., Tang, X. and Cui, F.D. (2004), Solid lipid namoparticles (SLNs) to improve oral bioavailability of poorly soluble drugs. Journal of Pharmacy and Pharmacology, 56 (12), 1527-1535. 246. Nozaki, Y., Yamagata, T., Yoo, B.S., Sugiyama, M., Ikoma, S., Kinoshita, K., Funauchi, M. and Kanamaru, A. (2005), The beneficial effects of treatment with all-trans-retinoic acid plus corticosteroid on autoimmune nephritis in NZB/WF1 mice. Clinical and Experimental Immunology, 139 (1), 74-83. 247. Zhao, K.W., Li, X., Zhao, Q., Huang, Y., Li, D., Peng, Z.G., Shen, W.Z., Zhao, J., Zhou, Q.S., Chen, Z., Sims, P.J., Wiedmer, T. and Chen, G.Q. (2004), Protein kinase C delta mediates retinoic acid and phorbol myristate acetate-induced phospholipid scramblase 1 gene expression: its role in leukemic cell differentiation. Blood, 104 (12), 3731-3738. 248. Elmazar, M.M.A. and Nau, H. (2004), Potentiation of the teratogenic effects induced by coadministration of retinoic acid or phytanic acid/phytol with synthetic retinoid receptor ligands. Archives of Toxicology, 78 (11), 660-668. 249. Niles, R.M. (2004), Signaling pathways in retinoid chemoprevention and treatment of cancer. Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis, 555 (1-2), 81-96. 250. Kambhampati, S., Verma, A., Li, Y.Z., Parmar, S., Sassano, A. and Platanias, L.C. (2004), Signalling pathways activated by all-trans-retinoic acid in acute promyelocytic leukemia cells. Leukemia & Lymphoma, 45 (11), 2175-2185. 251. Rice, A.M., Holtz, K.M., Karp, J., Rollins, S. and Sartorelli, A.C. (2004), Analysis of the relationship between Scl transcription factor complex protein expression patterns and the effects of LiCl on ATRA-induced differentiation in blast cells from patients with acute myeloid leukemia. Leukemia Research, 28 (11), 1227-1237. 252. Suzuki, N., Aoki, D., Oie, S., Horiuchi, M., Hasegawa, Y., Ezawa, S., Suzuki, A., Susumu, N., Hosoi, F., Kitazato, K. and Nozawa, S. (2004), A novel retinoid, 4-[3,5-bis (trimethylsilyl) benzamido] benzoic acid (TAC-101), induces apoptosis of human ovarian carcinoma cells and shows potential as a new antitumor agent for clear cell adenocarcinoma. Gynecologic Oncology, 94 (3), 643-649. 253. Kawamata, H., Fujimori, T. and Imai, Y. (2004), TSC-22 (TGF-beta stimulated clone-22): A novel molecular target for differentiation-inducing therapy in salivary gland cancer. Current Cancer Drug Targets, 4 (6), 521-529. 254. Zink, D., Fischer, A.H. and Nickerson, J.A. (2004), Nuclear structure in cancer cells. Nature Reviews Cancer, 4 (9), 677-687. 255. Chow, S.K.Y., Chan, J.Y.W. and Fung, K.P. (2004), Suppression of cell proliferation and regulation of estrogen receptor alpha signaling pathway by arsenic trioxide on human breast cancer MCF-7 cells. Journal of Endocrinology, 182 (2), 325-337. 256. Liu, L., Berletch, J.B., Green, J.G., Pate, M.S., Andrews, L.G. and Tollefsbol, T.O. (2004), Telomerase inhibition by retinoids precedes cytodifferentiation of leukemia cells and may contribute to terminal differentiation. Molecular Cancer Therapeutics, 3 (8), 1003-1009. 257. Tallman, M.S., Lefebvre, P., Baine, R.M., Shoji, M., Cohen, I., Green, D., Kwaan, H.C., Paietta, E. and Rickles, F.R. (2004), Effects of all-trans retinoic acid or chemotherapy on the molecular regulation of systemic blood coagulation and fibrinolysis in patients with acute promyelocytic leukemia. Journal of Thrombosis and Haemostasis, 2 (8), 1341-1350. 258. Kim, I.S., Kim, Y.S., Jang, S.W., Sung, H.J., Han, K.H., Na, D.S. and Ko, J. (2004), Differential effects of 9-cis retinoic acid on expression of CC chemokine receptors in human monocytes. Biochemical Pharmacology, 68 (4), 611-620. 259. Ishii, Y., Kiyota, H., Sakai, S. and Honma, Y. (2004), Induction of differentiation of human myeloid leukemia cells by jasmonates, plant hormones. Leukemia, 18 (8), 1413-1419. 260. Soprano, D.R., Qin, P. and Soprano, K.J. (2004), Retinoic acid receptors and cancers. Annual Review of Nutrition, 24), 201-221.
  17. 17. 17 261. Lei, M. and de The, H. (2003), Retinoids and retinoic acid receptor in cancer. Ejc Supplements, 1 (2), 13-18. 262. Nakaya, K. (2004), Basic studies for the development of anticancer, antidementia, and taste modifier drugs. Yakugaku Zasshi-Journal of the Pharmaceutical Society of Japan, 124 (7), 371-396. 263. Okuno, M., Kojima, S., Matsushima-Nishiwaki, R., Tsurumi, H., Muto, Y., Friedman, S.L. and Moriwaki, H. (2004), Retinoids in cancer chemoprevention. Current Cancer Drug Targets, 4 (3), 285-298. 264. Horie, N., Mori, T., Asada, H., Ishikawa, A., Johnston, P.G. and Takeshi, K. (2004), Implication of CDK inhibitors p21 and p27 in the differentiation of HL-60 cells. Biological & Pharmaceutical Bulletin, 27 (7), 992-997. 265. Martinez-Mancilla, M., Zafra, G., Reynoso-Gomez, E., Martinez-Avalos, A., Rivera-Luna, R. and Gariglio, P. (2004), A closer look at specific therapeutic strategies in leukemia. Leukemia & Lymphoma, 45 (9), 1767-1773. 266. Puccetti, E. and Ruthardt, M. (2004), Acute promyelocytic leukemia: PML/RAR alpha and the leukemic stem cell. Leukemia, 18 (7), 1169-1175. 267. Chen, Q.Y. and Ross, A.C. (2004), Retinoic acid regulates cell cycle progression and cell differentiation in human monocytic THP-1 cells. Experimental Cell Research, 297 (1), 68-81. 268. Murrin, R.J.A., Adjetey, V., Harrison, P. and Warwick, A. (2004), Acute promyelocytic leukaemia presenting as postpartum haemorrhage. Clinical and Laboratory Haematology, 26 (3), 233-237. 269. Kuo, M.C., Dunn, P., Wu, J.H. and Shih, L.Y. (2004), All-trans-retinoic acid-induced erythema nodosum in patients with acute promyelocytic leukemia. Annals of Hematology, 83 (6), 376-380. 270. Yang, M.J., Chen, T.Y., Han, C.F., Li, N., Wan, T. and Cao, X.T. (2004), Rab7b, a novel lysosome-associated small GTPase, is involved in monocytic differentiation of human acute promyelocytic leukemia cells. Biochemical and Biophysical Research Communications, 318 (3), 792-799. 271. Witcher, M. and Miller, W.H. (2004), Cytokines and retinoic acid therapy for APL: new tricks from an old combination. Leukemia Research, 28 (5), 447-448. 272. Pitha-Rowe, I., Hassel, B.A. and Dmitrovsky, E. (2004), Involvement of UBE1L in ISG15 conjugation during retinoid-induced differentiation of acute promyelocytic leukemia. Journal of Biological Chemistry, 279 (18), 18178-18187. 273. Bradley, D. (2004), Biography of Zhu Chen. Proceedings of the National Academy of Sciences of the United States of America, 101 (15), 5325-5327. 274. Shen, Z.X., Shi, Z.Z., Fang, J., Gu, B.W., Li, J.M., Zhu, Y.M., Shi, J.Y., Zheng, P.Z., Yan, H., Liu, Y.F., Chen, Y., Shen, Y., Wu, W., Tang, W., Waxman, S., de The, H., Wang, Z.Y., Chen, S.J. and Chen, Z. (2004), All-trans retinoic acid/AS(2)O(3) combination yields a high quality remission and survival in newly diagnosed acute promyelocytic leukemia. Proceedings of the National Academy of Sciences of the United States of America, 101 (15), 5328-5335. 275. de Botton, S., Coiteux, V., Chevret, S., Rayon, C., Vilmer, E., Sanz, M., de La Serna, J., Philippe, N., Baruchel, A., Leverger, G., Robert, A., Miguel, J.S., Conde, E., Sotto, J.J., Bordessoule, D., Fegueux, N., Fey, M., Parry, A., Chomienne, C., Degos, L. and Fenaux, P. (2004), Outcome of childhood acute promyelocytic leukemia with all-trans-retinoic acid and chemotherapy. Journal of Clinical Oncology, 22 (8), 1404-1412. 276. Navakauskiene, R., Treigyte, G., Gineitis, A. and Magnusson, K.E. (2004), Identification of apoptotic tyrosine-phosphorylated proteins after etoposide or retinoic acid treatment of HL-60 cells. Proteomics , 4 (4), 1029-1041. 277. Zhang, H.J., Wang, Z. and Zhou, J.B. (2004), Cytoplasm prepared from all-trans retinoic acid (ATRA)-treated human hematopoietic progenitor cells induces differentiation of both ATRA sensitive and ATRA resistant leukemia cells. Biological & Pharmaceutical Bulletin, 27 (4), 570-573.
  18. 18. 18 278. Jeong, Y.I., Kang, M.K., Sun, H.S., Kang, S.S., Kim, H.W., Moon, K.S., Lee, K.J., Kim, S.H. and Jung, S. (2004), All-trans-retinoic acid release from core-shell type nanoparticles of poly (epsilon-caprolactone)/poly (ethylene glycol) diblock copolymer. International Journal of Pharmaceutics, 273 (1-2), 95-107. 279. Kojima, S., Okuno, M., Matsushima-Nishiwaki, R., Friedman, S.L. and Moriwaki, H. (2004), Acyclic retinoid in the chemoprevention of hepatocellular carcinoma (Review). International Journal of Oncology, 24 (4), 797-805. 280. Cuendet, M., Gills, J.J. and Pezzuto, J.M. (2004), Brusatol-induced HL-60 cell differentiation involves NF-kappa B activation. Cancer Letters, 206 (1), 43-50. 281. Wang, J.R. and Yen, A. (2004), A novel retinoic acid-responsive element regulates retinoic acid-induced BLR1 expression. Molecular and Cellular Biology, 24 (6), 2423-2443. 282. Prus, E., Chandraratna, R.A.S. and Fibach, E. (2004), Retinoic acid receptor antagonist inhibits CD38 antigen expression on human hematopoietic cells in vitro. Leukemia & Lymphoma, 45 (5), 1025-1035. 283. Cuendet, M. and Pezzuto, J.M. (2004), Antitumor activity of bruceantin: An old drug with new promise. Journal of Natural Products, 67 (2), 269-272. 284. Takamura, K., Nasuhara, Y., Kobayashi, M., Betsuyaku, T., Tanino, Y., Kinoshita, I., Yamaguchi, E., Matsukura, S., Schleimer, R.P. and Nishimura, M. (2004), Retinoic acid inhibits interleukin-4-induced eotaxin production in a human bronchial epithelial cell line. American Journal of Physiology-Lung Cellular and Molecular Physiology, 286 (4), L777-L785. 285. Evans, W.E. and Guy, R.K. (2004), Gene expression as a drug discovery tool. Nature Genetics, 36 (3), 214-215. 286. Stegmaier, K., Ross, K.N., Colavito, S.A., O'Malley, S., Stockwell, B.R. and Golub, T.R. (2004), Gene expression-based high-throughput screening (GE-HTS) and application to leukemia differentiation. Nature Genetics, 36 (3), 257-263. 287. Consoli, U., Figuera, A., Milone, G., Meli, C.R., Guido, G., Indelicato, F., Moschetti, G., Leotta, S., Tornello, A., Poidomani, M., Murgano, P., Pinto, V. and Giustolisi, R. (2004), Acute promyelocytic leukemia during pregnancy: Report of 3 cases. International Journal of Hematology , 79 (1), 31-36. 288. Gomez-Vidal, J.A., Campos, J., Marchal, J.A., Boulaiz, H., Gallo, M.A., Carrillo, E., Espinosa, A. and Aranega, A. (2004), Actual targets in cytodifferentiation cancer therapy. Current Topics in Medicinal Chemistry, 4 (2), 175-202. 289. Ji, Y. and Studzinski, G.P. (2004), Retinoblastoma protein and CCAAT/enhancer-binding protein beta are required for 1,25-dihydroxyvitamin D-3-induced monocytic differentiation of HL60 cells. Cancer Research, 64 (1), 370-377. 290. Zhao, Q., Tao, J., Zhu, Q., Jia, P.M., Dou, A.X., Li, X., Cheng, F., Waxman, S., Chen, G.Q., Chen, S.J., Lanotte, M., Chen, Z. and Tong, J.H. (2004), Rapid induction of cAMP/PKA pathway during retinoic acid-induced acute promyelocytic leukemia cell differentiation. Leukemia, 18 (2), 285-292. 291. Mizukami, Y., Sumimoto, H. and Takeshige, K. (2004), Induction of cytochrome CYP4F3A in all-trans-retinoic acid-treated HL60 cells. Biochemical and Biophysical Research Communications, 314 (1), 104-109. 292. Lazar, M.A. (2004), East meets West: an herbal tea finds a receptor. Journal of Clinical Investigation, 113 (1), 23-25. 293. Han, Z.G., Zhao, G.P. and Chen, Z. (2003), Transcriptome study in China. Comptes Rendus Biologies, 326 (10-11), 949-957. 294. Guirgis, M.F. and Lueder, G.T. (2003), Intracranial hypertension secondary to all-trans retinoic acid treatment for leukemia: Diagnosis and management. Journal of Aapos, 7 (6), 432-434. 295. Vorobyev, A.I., Vorobyev, I.A., Gretsov, E.M., Kremenetskaya, A.M., Korneva, A.M., Magomedova, A.U., Kharazishvili, D.V., Khudoleeva, O.A. and Chernova, N.G. (2003), Problems of theoretical hematology. Terapevticheskii Arkhiv, 75 (9), 22-29.
  19. 19. 19 296. Jing, Y.K. (2004), The PML-RAR alpha fusion protein and targeted therapy for acute promyelocytic leukemia. Leukemia & Lymphoma, 45 (4), 639-648. 297. Kempf, W., Kettelhack, N., Duvic, M. and Burg, G. (2003), Topical and systemic retinoid therapy for cutaneous T-cell lymphoma. Hematology-Oncology Clinics of North America, 17 (6), 1405-+. 298. Avvisati, G. and Tallman, M.S. (2003), All-trans retinoic acid in acute promyelocytic leukaemia. Best Practice & Research Clinical Haematology, 16 (3), 419-432. 299. Sanz, M.A., Martin, G. and Lo Coco, F. (2003), Choice of chemotherapy in induction, consolidation and maintenance in acute promyelocytic leukaemia. Best Practice & Research Clinical Haematology, 16 (3), 433-451. 300. Inagaki, T., Suzuki, S., Miyamoto, T., Takeda, T., Yamashita, K., Komatsu, A., Yamauchi, K. and Hashizume, K. (2003), The retinoic acid-responsive proline-rich protein is identified in promyeloleukemic HL-60 cells. Journal of Biological Chemistry, 278 (51), 51685-51692. 301. Baranova, O.Y., Frenkel, M.A., Volkova, M.A. and Tupitsyn, N.N. (2003), Acute promyelocytic leukemia: Problems of diagnosis and current therapeutic opportunities. Gematologiya I Transfuziologiya, 48 (4), 3-10. 302. Adachi, S., Leoni, L.M., Carson, D.A. and Nakahata, T. (2003), Apoptosis induced by molecular targeting therapy in hematological malignancies. Acta Haematologica, 111 (1-2), 107-123. 303. Nakagawa, S., Fujii, T., Yokoyama, G., Kazanietz, M.G., Yamana, H. and Shirouzu, K. (2003), Cell growth inhibition by all-trans retinoic acid in SKBR-3 breast cancer cells: Involvement of protein kinase C alpha and extracellular signal-regulated kinase mitogen-activated protein kinase. Molecular Carcinogenesis, 38 (3), 106-116. 304. Malone, W., Perloff, M., Crowell, J., Sigman, C. and Higley, H. (2003), Fenretinide: a prototype cancer prevention drug. Expert Opinion on Investigational Drugs, 12 (11), 1829-1842. 305. Yang, L.J., Zhao, H.S., Li, S.W., Ahrens, K., Collins, C., Eckenrode, S., Ruan, Q.G., McIndoe, R.A. and She, J.X. (2003), Gene expression profiling during all-trans retinoic acid-induced cell differentiation of acute promyelocytic leukemia cells. Journal of Molecular Diagnostics, 5 (4), 212-221. 306. Moog-Lutz, C., Cave-Riant, F., Guibal, F.C., Breau, M.A., Di Gioia, Y., Couraud, P.O., Cayre, Y.E., Bourdoulous, S. and Lutz, P.G. (2003), JAML, a novel protein with characteristics of a junctional adhesion molecule, is induced during differentiation of myeloid leukemia cells. Blood, 102 (9), 3371-3378. 307. Galsky, M. and Kelly, W.K. (2003), The development of differentiation agents for the treatment of prostate cancer. Seminars in Oncology, 30 (5), 689-697. 308. Mann, K.K., Rephaeli, A., Colosimo, A.L., Diaz, Z., Nudelman, A., Levovich, I., Jing, H.K., Waxman, S. and Miller, W.H. (2003), A retinoid/butyric acid prodrug overcomes retinoic acid resistance in leukemias by induction of apoptosis. Molecular Cancer Research, 1 (12), 903-912. 309. Dong, S., Chen, S.J. and Tweardy, D.J. (2003), Cross-talk between retinoic acid and Stat3 signaling pathways in acute promyelocytic leukemia. Leukemia & Lymphoma, 44 (12), 2023-2029. 310. Ikezoe, T., Chen, S., Saito, T., Asou, H., Kyo, T., Tanosaki, S., Heber, D., Taguchi, H. and Koeffler, H.P. (2003), PC-SPES decreases proliferation and induces differentiation and apoptosis of human acute myeloid leukemia cells. International Journal of Oncology, 23 (4), 1203-1211. 311. Oren, T., Sher, J.A. and Evans, T. (2003), Hematopoiesis and retinoids: Development and disease. Leukemia & Lymphoma, 44 (11), 1881-1891. 312. Barbey, J.T., Pezzullo, J.C. and Soignet, S.L. (2003), Effect of arsenic trioxide on QT interval in patients with advanced malignancies. Journal of Clinical Oncology, 21 (19), 3609-3615.
  20. 20. 20 313. Lengfelder, E., Gnad, U., Buchner, T. and Hehlmann, R. (2003), Treatment of relapsed acute promyelocytic leukemia. Onkologie , 26 (4), 373-379. 314. Pitha-Rowe, I., Petty, W.J., Kitareewan, S. and Dmitrovsky, E. (2003), Retinoid target genes in acute promyelocytic leukemia. Leukemia, 17 (9), 1723-1730. 315. Honma, Y., Ishii, Y., Sassa, T. and Asahi, K. (2003), Treatment of human promyelocytic leukemia in the SLID mouse model with cotylenin A, an inducer of myelomonocytic differentiation of leukemia cells. Leukemia Research, 27 (11), 1019-1025. 316. Kambhampati, S., Li, Y.Z., Verma, A., Sassano, A., Majchrzak, B., Deb, D.K., Parmar, S., Giafis, N., Kalvakolanu, D.V., Rahman, A., Uddin, S., Minucci, S., Tallman, M.S., Fish, E.N. and Platanias, L.C. (2003), Activation of protein kinase C delta by all-trans-retinoic acid. Journal of Biological Chemistry, 278 (35), 32544-32551. 317. Rishi, A.K., Zhang, L.Y., Boyanapalli, M., Wali, A., Mohammad, R.M., Yu, Y.J., Fontana, J.A., Hatfield, J.S., Dawson, M.I., Majumdar, A.P.N. and Reichert, U. (2003), Identification and characterization of a cell cycle and apoptosis regulatory protein-1 as a novel mediator of apoptosis signaling by retinoid CD437. Journal of Biological Chemistry, 278 (35), 33422-33435. 318. Yuasa, Y. (2003), Control of gut differentiation and intestinal-type gastric carcinogenesis. Nature Reviews Cancer, 3 (8), 592-600. 319. Casillas, J.N., Woods, W.G., Hunger, S.P., McGavran, L., Alonzo, T.A. and Feig, S.A. (2003), Prognostic implications of t(10;11) translocations in childhood acute myelogenous leukemia: A report from the Children's Cancer Group. Journal of Pediatric Hematology Oncology, 25 (8), 594-600. 320. Moller, A., Sirma, H., Hofmann, T.G., Rueffer, S., Klimczak, E., Droge, W., Will, H. and Schmitz, M.L. (2003), PML is required for homeodomain-interacting protein kinase 2 (HIPK2)-mediated p53 phosphorylation and cell cycle arrest but is dispensable for the formation of HIPK domains. Cancer Research, 63 (15), 4310-4314. 321. Degos, L. (2003), The history of acute promyelocytic leukaemia. British Journal of Haematology, 122 (4), 539-553. 322. Kawamata, H., Ornotehara, F., Nakashiro, K., Uchida, D., Hino, S. and Fujimori, T. (2003), Vesnarinone: a differentiation-inducing anti-cancer drug. Anti-Cancer Drugs, 14 (6), 391-395. 323. Ohno, R., Asou, N. and Ohnishi, K. (2003), Treatment of acute promyelocytic leukemia: strategy toward further increase of cure rate. Leukemia, 17 (8), 1454-1463. 324. Savickiene, J. and Gineitis, A. (2003), 3-Deazauridine triggers dose-dependent apoptosis in myeloid leukemia cells and enhances retinoic acid-induced granulocytic differentiation of HL-60 cells. International Journal of Biochemistry & Cell Biology, 35 (10), 1482-1494. 325. Parmar, S. and Tallman, M.S. (2003), Acute promyelocytic leukaemia: a review. Expert Opinion on Pharmacotherapy, 4 (8), 1379-1392. 326. Yamamoto-Yamaguchi, Y., Okabe-Kado, J., Kasukabe, T. and Honma, Y. (2003), Induction of apoptosis by combined treatment with differentiation-inducing agents and interferon-alpha in human lung cancer cells. Anticancer Research, 23 (3B), 2537-2547. 327. Ivanova, D., Vassileva, M., Vassileva, N., Pashkuleva, I. and Koleva, R. (2003), Stereoselective synthesis of new coumarin and N-methylcarbazole retinoic acid analogs. Journal of the Indian Chemical Society, 80 (6), 650-653. 328. Ratnam, M., Hao, H., Zhen, X., Wang, H., Qi, H.L., Lee, R. and Pan, X. (2003), Receptor induction and targeted drug delivery: a new antileukaemia strategy. Expert Opinion on Biological Therapy, 3 (4), 563-574. 329. Weinzweig, J., Tattini, C., Lynch, S., Zienowicz, R., Weinzweig, N., Spangenberger, A. and Edstrom, L. (2003), Investigation of the growth and metastasis of malignant melanoma in a murine model: The role of supplemental vitamin A. Plastic and Reconstructive Surgery, 112 (1), 152-158.
  21. 21. 21 330. Takahashi, N., Tamagawa, K., Shimizu, K., Fukui, T. and Maitani, Y. (2003), Effects on M5076-hepatic metastasis of retinoic acid and N-(4-hydroxyphenyl) retinamide, fenretinide entrapped in SG-liposomes. Biological & Pharmaceutical Bulletin, 26 (7), 1060-1063. 331. Jing, Y., Xia, L.J., Lu, M. and Waxman, S. (2003), The cleavage product Delta PML-RAR alpha contributes to all-trans retinoic acid-mediated differentiation in acute promyelocytic leukemia cells. Oncogene, 22 (26), 4083-4091. 332. Clarkson, B., Strife, A., Wisniewski, D., Lambek, C.L. and Liu, C. (2003), Chronic myelogenous leukemia as a paradigm of early cancer and possible curative strategies. Leukemia, 17 (7), 1211-1262. 333. Cai, X., Yu, Y., Huang, Y., Zhang, L., Jia, P.M., Zhao, Q., Chen, Z., Tong, J.H., Dai, W. and Chen, G.Q. (2003), Arsenic trioxide-induced mitotic arrest and apoptosis in acute promyelocytic leukemia cells. Leukemia, 17 (7), 1333-1337. 334. Raffoux, E., Rousselot, P., Poupon, J., Daniel, M.T., Cassinat, B., Delarue, R., Taksin, A.L., Rea, D., Buzyn, A., Tibi, A., Lebbe, G., Cimerman, P., Chomienne, C., Fermand, J.P., de The, H., Degos, L., Hermine, O. and Dombret, H. (2003), Combined treatment with arsenic trioxide and all-trans-retinoic acid in patients with relapsed acute promyelocytic leukemia. Journal of Clinical Oncology, 21 (12), 2326-2334. 335. Young, J.I., Song, J.G., Kang, S.S., Ryu, H.H., Lee, Y.H., Choi, C., Shin, B.A., Kim, K.K., Ahn, K.Y. and Jung, S. (2003), Preparation of poly(DL-lactide-co-glycolide) microspheres encapsulating all-trans retinoic acid. International Journal of Pharmaceutics, 259 (1-2), 79-91. 336. Honma, Y. (2003), Adenine analogs as potential differentiation therapy agents for acute myeloid leukemia. Drug Development Research, 59 (1), 14-22. 337. Flanagan, S.A. and Meckling, K.A. (2003), All-trans-retinoic acid increases cytotoxicity of 1-beta-D-arabinofuranosylcytosine in NB4 cells. Cancer Chemotherapy and Pharmacology, 51 (5), 363-375. 338. Iwata, K., Ogata, S., Okumura, K. and Taguchi, H. (2003), Induction of differentiation in human promyelocytic leukemia HL-60 cell line by niacin-related compounds. Bioscience Biotechnology and Biochemistry, 67 (5), 1132-1135. 339. Oduncu, F.S., Kimmig, R., Hepp, H. and Emmerich, B. (2003), Cancer in pregnancy: maternal-fetal conflict. Journal of Cancer Research and Clinical Oncology, 129 (3), 133-146. 340. Felsher, D.W. (2003), Cancer revoked: oncogenes as therapeutic targets. Nature Reviews Cancer, 3 (5), 375-380. 341. Kinoshita, K., Yoo, B.S., Nozaki, Y., Sugiyama, M., Ikoma, S., Ohno, M., Funauchi, M. and Kanamaru, A. (2003), Retinoic acid reduces autoimmune renal injury and increases survival in NZB/W F-1 mice. Journal of Immunology, 170 (11), 5793-5798. 342. Gaines, P. and Berliner, N. (2003), Retinoids in myelopolesis. Journal of Biological Regulators and Homeostatic Agents, 17 (1), 46-65. 343. Novitzky, N., Thomas, V. and Stubbings, H. (2003), Intensified myeloablative therapy and autologous stem-cell transplantation for patients with AML: single center experience. Cytotherapy, 5 (2), 139-146. 344. Kao, H.W., Chen, H.C., Wu, C.W. and Lin, W.C. (2003), Tyrosine-kinase expression profiles in human gastric cancer cell lines and their modulations with retinoic acids. British Journal of Cancer, 88 (7), 1058-1064. 345. Lazo, G., Kantarjian, H., Estey, E., Thomas, D., O'Brien, S. and Cortes, J. (2003), Use of arsenic trioxide (AS(2)O(3)) in the treatment of patients with acute promyelocytic leukemia - The M. D. Anderson experience. Cancer, 97 (9), 2218-2224. 346. Douer, D., Hu, W., Giralt, S., Lill, M. and DiPersio, J. (2003), Arsenic trioxide (Trisenox (R)) therapy for acute promyelocytic leukemia in the setting of hematopoietic stem cell transplantation. Oncologist, 8 (2), 132-140. 347. Doherty, M.M. and Michael, M. (2003), Tumoral drug metabolism: Perspectives and therapeutic implications. Current Drug Metabolism, 4 (2), 131-149.
  22. 22. 22 348. Lanvers, C., Reinhardt, D., Dubbers, A., Wagner-Bohn, A., Creutzig, U., Ritter, J. and Boos, J. (2003), Pharmacology of all-trans-retinoic acid in children with acute promyelocytic leukemia. Medical and Pediatric Oncology, 40 (5), 293-301. 349. Esteva, F.J., Glaspy, J., Baidas, S., Laufman, L., Hutchins, L., Dickler, M., Tripathy, D., Cohen, R., DeMichele, A., Yocum, R.C., Osborne, C.K., Hayes, D.F., Hortobagyi, G.N., Winer, E. and Demetri, G.D. (2003), Multicenter phase II study of oral bexarotene for patients with metastatic breast cancer. Journal of Clinical Oncology, 21 (6), 999-1006. 350. Ichiishi, E., Yoshikawa, T., Takai, T., Tokuda, H., Yoshida, Y., Hanashiro, K., Kaminuma, T., Yoshida, N. and Nishino, H. (2001), Effect of retinoic acid on cell proliferation-related gene expression in Raji cells induced by 12-O-tetra-decanoylphorbol-13-acetate. Journal of Clinical Biochemistry and Nutrition, 30), 21-31. 351. Ponthan, F., Johnsen, J.I., Klevenvall, L., Castro, J. and Kogner, P. (2003), The synthetic retinoid Ro 13-6307 induces neuroblastoma differentiation in vitro and inhibits neuroblastoma tumour growth in vivo. International Journal of Cancer, 104 (4), 418-424. 352. Chung, C.Y., Hsu, N.C., Horng, H.C. and Chang, C.S. (2003), Successful treatment for multiple cerebral hemorrhage in a newly diagnosed patient with acute promyelocytic leukemia. Leukemia & Lymphoma, 44 (6), 1059-1061. 353. Asou, N. (2003), The role of a Runt domain transcription factor AML1/RUNX1 in leukemogenesis and its clinical implications. Critical Reviews in Oncology Hematology, 45 (2), 129-150. 354. Prus, E. and Fibach, E. (2003), Retinoic acid induction of CD38 antigen expression on normal and leukemic human myeloid cells: Relationship with cell differentiation. Leukemia & Lymphoma, 44 (4), 691-698. 355. Teraishi, F., Kadowaki, Y., Tango, Y., Kawashima, T., Umeoka, T., Kagawa, S., Tanaka, N. and Fujiwara, T. (2003), Ectopic p21(sdi1) gene transfer induces retinoic acid receptor beta expression and sensitizes human cancer cells to retinoid treatment. International Journal of Cancer, 103 (6), 833-839. 356. Moreno, I., Martin, G., Bolufer, P., Barragan, E., Rueda, E., Roman, J., Fernandez, P., Leon, P., Mena, A., Cervera, J., Torres, A. and Sanz, M.A. (2003), Incidence and prognostic value of FLT3 internal tandem duplication and D835 mutations in acute myeloid leukemia. Haematologica, 88 (1), 19-24. 357. Truong, B.T.H., Lee, Y.J., Lodie, T.A., Park, D.J., Perrotti, D., Watanabe, N., Koeffler, H.P., Nakajima, H., Tenen, D.G. and Kogan, S.C. (2003), CCAAT/enhancer binding proteins repress the leukemic phenotype of acute myeloid leukemia. Blood, 101 (3), 1141-1148. 358. Rowley, J.D. (2001), Chromosome translocations: dangerous liaisons revisited. Nature Reviews Cancer, 1 (3), 245-250. 359. Zhu, J., Chen, Z., Lallemand-Breitenbach, V. and de The, H. (2002), How acute promyelocytic leukaemia revived arsenic. Nature Reviews Cancer, 2 (9), 705-713. 360. Lee, D.S., Lee, Y.S., Kim, Y.R., Han, K.S., Park, K.U., She, C.J., Kim, E.C., Park, S.Y. and Cho, H.I. (2002), RARA fluorescence in situ hybridization overcomes the drawback of PML/RARA fluorescence in situ hybridization in follow-up of acute promyelocytic leukemia. Cancer Genetics and Cytogenetics, 139 (2), 104-108. 361. Soprano, K.J. and Soprano, D.R. (2002), Retinoic acid receptors and cancer. Journal of Nutrition, 132 (12), 3809S-3813S. 362. Hirano, T., Kizaki, M., Kato, K., Abe, F., Masuda, N. and Umezawa, K. (2002), Enhancement of sensitivity by bestatin of acute promyelocytic leukemia NB4 cells to all-trans retinoic acid. Leukemia Research , 26 (12), 1097-1103. 363. Okuno, M., Moriwaki, H., Matsushima-Nishiwaki, R., Sano, T., Adachi, S., Akita, K. and Kojima, S. (2002), Retinoid-induced apoptosis in hepatocellular carcinoma: A molecular basis for "clonal deletion" therapy. Growth, Proliferation, and Apoptosis in Hepatocytes, ), 33-39.
  23. 23. 23 364. Okuno, M., Kojima, S. and Moriwaki, H. (2001), Chemoprevention of hepatocellular carcinoma: Concept, progress and perspectives. Journal of Gastroenterology and Hepatology, 16 (12), 1329-1335. 365. Mata-Greenwood, E., Cuendet, M., Sher, D., Gustin, D., Stock, W. and Pezzuto, J.M. (2002), Brusatol-mediated induction of leukemic cell differentiation and G(1) arrest is associated with down-regulation of c-myc. Leukemia, 16 (11), 2275-2284. 366. Niitsu, N., Higashihara, M. and Honma, Y. (2002), The catalytic DNA topoisomerase II inhibitor ICRF-193 and all-trans retinoic acid cooperatively induce granulocytic differentiation of acute promyelocytic leukemia cells: Candidate drugs for chemo-differentiation therapy against acute promyelocytic leukemia. Experimental Hematology, 30 (11), 1273-1282. 367. Douer, D. (2002), New advances in the treatment of acute promyelocytic leukemia. International Journal of Hematology, 76), 179-187. 368. Kawamura, C., Kizaki, M., Fukuchi, Y. and Ikeda, Y. (2002), A metal chelator, diphenylthiocarbazone, induces apoptosis in acute promyelocytic leukemia (APL) cells mediated by a caspase-dependent pathway without a modulation of retinoic acid signaling pathways. Leukemia Research, 26 (7), 661-668. 369. Thomas, X. and Le, Q.H. (2002), Treatment of relapsed adult acute myeloid leukemia. Bulletin du Cancer, 89 (9), 795-807. 370. Beard, R.L., Duong, T.T., Teng, M., Klein, E.S., Standevan, A.M. and Chandraratna, R.A.S. (2002), Synthesis and biological activity of retinoic acid receptor-alpha specific amides. Bioorganic & Medicinal Chemistry Letters, 12 (21), 3145-3148. 371. Collins, S.J. (2002), The role of retinoids and retinoic acid receptors in normal hematopoiesis. Leukemia, 16 (10), 1896-1905. 372. Strudwick, S. and Borden, K.L.B. (2002), Finding a role for PML in APL pathogenesis: a critical assessment of potential PML activities. Leukemia, 16 (10), 1906-1917. 373. Lutz, P.G., Moog-Lutz, C. and Cayre, Y.E. (2002), Signaling revisited in acute promyelocytic leukemia. Leukemia, 16 (10), 1933-1939. 374. Gallagher, R.E. (2002), Retinoic acid resistance in acute promyelocytic leukemia. Leukemia, 16 (10), 1940-1958. 375. Mozziconacci, M.J., Rosenauer, A., Restouin, A., Fanelli, M., Shao, W.L., Fernandez, F., Toiron, Y., Viscardi, J., Gambacorti-Passerini, C., Miller, W.H. and Lafage-Pochitaloff, M. (2002), Molecular cytogenetics of the acute promyelocytic leukemia-derived cell line NB4 and of four all-trans retinoic acid-resistant subclones. Genes Chromosomes & Cancer, 35 (3), 261-270. 376. Jackson, G.H. and Taylor, P.R.A. (2002), Acute myeloid leukaemia - Optimising treatment in elderly patients. Drugs & Aging, 19 (8), 571-581. 377. Mellinghoff, I.K. and Sawyers, C.L. (2002), The emergence of resistance to targeted cancer therapeutics. Pharmacogenomics, 3 (5), 603-623. 378. Battle, T.E. and Yen, A. (2002), Ectopic expression of CXCR5/BLR1 accelerates retinoic acid- and vitamin D-3-induced monocytic differentiation of U937 cells. Experimental Biology and Medicine, 227 (9), 753-762. 379. Dejean, A. (2002), Retinoic acid nuclear receptors : a common molecular basis for liver cancer and acute promyelopytic leukemia. Bulletin de l Academie Nationale de Medecine, 186 (4), 751-757. 380. Idres, N., Marill, J., Flexor, M.A. and Chabot, G.C. (2002), Activation of retinoic acid receptor-dependent transcription by all-trans-retinoic acid metabolites and isomers. Journal of Biological Chemistry, 277 (35), 31491-31498. 381. Honma, Y. and Ishii, Y. (2002), Differentiation of human myeloid leukemia cells by plant redifferentiation-inducing hormones. Leukemia & Lymphoma, 43 (9), 1729-1735. 382. Stone, R.M. (2002), New therapies in leukemia: Renewed hope. Journal of Hematotherapy & Stem Cell Research, 11 (4), 583-587.
  24. 24. 24 383. Muller, P., Kietz, S., Gustafsson, J.A. and Strom, A. (2002), The anti-estrogenic effect of all-trans-retinoic acid on the breast cancer cell line MCF-7 is dependent on HES-1 expression. Journal of Biological Chemistry, 277 (32), 28376-28379. 384. Takahashi, N. (2002), Induction of cell differentiation and development of new anticancer drugs. Yakugaku Zasshi-Journal of the Pharmaceutical Society of Japan, 122 (8), 547-563. 385. Kiyoi, H. and Naoe, T. (2002), FLT3 in human hematologic malignancies. Leukemia & Lymphoma, 43 (8), 1541-1547. 386. Jing, Y.K., Xia, L.J. and Waxman, S. (2002), Targeted removal of PML-RAR alpha protein is required prior to inhibition of histone deacetylase for overcoming all-trans retinoic acid differentiation resistance in acute promyelocytic leukemia. Blood, 100 (3), 1008-1013. 387. Siu, B.L., Alonzo, M.R., Vargo, T.A. and Fenrich, A.L. (2002), Transient dilated cardiomyopathy in a newborn exposed to idarubicin and all-trans-retinoic acid (ATRA) early in the second trimester of pregnancy. International Journal of Gynecological Cancer, 12 (4), 399-402. 388. Koistinen, P., Zheng, A., Saily, M., Siitonen, T., Mantymaa, P. and Savolainen, E.R. (2002), Superior effect of 9-cis retinoic acid (RA) compared with all-trans RA and 13-cis RA on the inhibition of clonogenic cellgrowth and the induction of apoptosis in OCI/AML-2 subclones: is the p53 pathway involved? British Journal of Haematology, 118 (2), 401-410. 389. Niitsu, N., Higashihara, M. and Honma, Y. (2002), Human B-cell lymphoma cell lines are highly sensitive to apoptosis induced by all-trans retinoic acid and interferon-gamma. Leukemia Research, 26 (8), 745-755. 390. Pan, X.Q., Zheng, X., Shi, G.F., Wang, H.Q., Ratnam, M. and Lee, R.J. (2002), Strategy for the treatment of acute myelogenous leukemia based on folate receptor beta-targeted liposomal doxorubicin combined with receptor induction using all-trans retinoic acid. Blood, 100 (2), 594-602. 391. Herault, O., Domenech, J., Georget, M.T., Clement, N., Colombat, P. and Binet, C. (2002), All-trans retinoic acid prevents apoptosis of human marrow CD34(+) cells deprived of haematopoietic growth factors. British Journal of Haematology, 118 (1), 289-295. 392. Jinno, H., Steiner, M.G., Nason-Burchenal, K., Osborne, M.P. and Telang, N.T. (2002), Preventive efficacy of receptor class selective retinoids on HER-2/neu oncogene expressing preneoplastic human mammary epithelial cells. International Journal of Oncology, 21 (1), 127-134. 393. Asou, H., Koshizuka, K., Kyo, T., Takata, N., Kamada, N. and Koeffler, H.P. (2002), Resveratrol, a natural product derived from grapes, is a new inducer of differentiation in human myeloid leukemias. International Journal of Hematology, 75 (5), 528-533. 394. Ozpolat, B. and Lopez-Berestein, G. (2002), Liposomal-all-trans-retinoic acid in treatment of acute promyelocytic leukemia. Leukemia & Lymphoma, 43 (5), 933-941. 395. Honma, Y. (2002), Cotylenin A - A plant growth regulator as a differentiation-inducing agent against myeloid leukemia. Leukemia & Lymphoma, 43 (6), 1169-1178. 396. Yasuda, I., Shiratori, Y., Adachi, S., Obora, A., Takemura, M., Okuno, M., Shidoji, Y., Seishima, M., Muto, Y. and Moriwaki, H. (2002), Acyclic retinoid induces partial differentiation, down-regulates telomerase reverse transcriptase mRNA expression and telomerase activity, and induces apoptosis in human hepatoma-derived cell lines. Journal of Hepatology, 36 (5), 660-671. 397. Gu, B.W., Xiong, H., Zhou, Y., Chen, B., Wang, L., Dong, S., Yu, Z.Y., Lu, L.F., Zhong, M., Yin, H.F., Zhu, G.F., Huang, W., Ren, S.X., Gallagher, R.E., Waxman, S., Chen, G.Q., Wang, Z.G., Chen, Z., Fu, G. and Chen, S.J. (2002), Variant-type PML-RAR alpha fusion transcript in acute promyelocytic leukemia: Use of a cryptic coding sequence from intron 2 of the RAR alpha gene and identification of a new clinical subtype resistant to retinoic acid therapy. Proceedings of the National Academy of Sciences of the United States of America, 99 (11), 7640-7645.
  25. 25. 25 398. Sakamoto, O., Yoshinari, M., Rikiishi, T., Fujiwara, I., Imaizumi, M., Tsuchiya, S. and Iinuma, K. (2001), Hypercalcemia due to all-trans retinoic acid therapy for acute promyelocytic leukemia: A case report of effective treatment with bisphosphonate. Pediatrics International, 43 (6), 688-690. 399. Scandura, J.M., Boccuni, P., Cammenga, J. and Nimer, S.D. (2002), Transcription factor fusions in acute leukemia: variations on a theme. Oncogene, 21 (21), 3422-3444. 400. Miller, W.H. and Waxman, S. (2002), Differentiation induction as a treatment for hematologic malignancies. Oncogene, 21 (21), 3496-3506. 401. Pendino, F., Sahraoui, T., Lanotte, M. and Sega-Bendirdjian, E. (2002), A novel mechanism of retinoic acid resistance in acute promyelocytic leukemia cells through a defective pathway in telomerase regulation. Leukemia, 16 (5), 826-832. 402. Rybner, C., Hillion, J., Sahraoui, T., Lanotte, M. and Botti, J. (2002), All-trans retinoic acid down-regulates prion protein expression independently of granulocyte maturation. Leukemia, 16 (5), 940-948. 403. Sharma, R.A. (2002), The advancement of cancer chemoprevention by revision of clinical trial strategies. Panminerva Medica, 44 (1), 41-45. 404. Prufer, K., Schroder, C., Hegyi, K. and Barsony, J. (2002), Degradation of RXRs influences sensitivity of rat osteosarcoma cells to the antiproliferative effects of calcitriol. Molecular Endocrinology, 16 (5), 961-976. 405. Strudwick, S. and Borden, K.L.B. (2002), The emerging roles of translation factor eIF4E in the nucleus. Differentiation, 70 (1), 10-22. 406. Hummel, J.L., Zhang, T., Wells, R.A. and Kamel-Reid, S. (2002), The retinoic acid receptor alpha (RAR alpha) chimeric proteins PML-, PLZF-, NPM-, and NuMA-RAR alpha have distinct intracellular localization patterns. Cell Growth & Differentiation, 13 (4), 173-183. 407. Lu, D.P., Qiu, J.Y., Jiang, B., Wang, Q., Liu, K.Y., Liu, Y.R. and Chen, S.S. (2002), Tetra-arsenic tetra-sulfide for the treatment of acute promyelocytic leukemia: a pilot report. Blood, 99 (9), 3136-3143. 408. Soignet, S.L. (2001), Clinical experience of arsenic trioxide in relapsed acute promyelocytic leukemia. Oncologist, 6), 11-16. 409. Fontana, J.A. and Rishi, A.K. (2002), Classical and novel retinoids: their targets in cancer therapy. Leukemia, 16 (4), 463-472. 410. Ohnishi, K., Yoshida, H., Shigeno, K., Nakamura, S., Fujisawa, S., Naito, K., Shinjo, K., Fujita, Y., Matsui, H., Sahara, N., Takeshita, A., Satoh, H., Terada, H. and Ohno, R. (2002), Arsenic trioxide therapy for relapsed or refractory Japanese patients with acute promyelocytic leukemia: need for careful electrocardiogram monitoring. Leukemia, 16 (4), 617-622. 411. Slack, J.L., Waxman, S., Tricot, G., Tallman, M.S. and Bloomfield, C.D. (2002), Advances in the management of acute promyelocytic leukemia and other hematologic malignancies with arsenic trioxide. Oncologist, 7), 1-13. 412. Odani, T., Kohroki, J., Nakanishi, T., Itoh, N., Muto, N. and Tanaka, K. (2000), Enhancement by dimethyl sulfoxide of 1,25-dihydroxyvitamin D(3-)induced differentiation in human promyelocytic HL-60 leukemia cells requires dimethyl sulfoxide-induced G(0)/G(1) arrest. Research Communications in Molecular Pathology and Pharmacology, 108 (5-6), 381-391. 413. Cellai, C., Laurenzana, A., Vannucchi, A.M., la Malva, N., Bianchi, L. and Paoletti, F. (2002), Specific PAF antagonist WEB-2086 induces terminal differentiation of murine and human leukemia cells. Faseb Journal, 16 (3), 733-+. 414. Kagechika, H. (2002), Novel synthetic retinoids and separation of the pleiotropic retinoidal activities. Current Medicinal Chemistry, 9 (5), 591-608. 415. Le Beau, M.M., Bitts, S., Davis, E.M. and Kogan, S.C. (2002), Recurring chromosomal abnormalities in leukemia in PML-RARA transgenic mice parallel human acute promyelocytic leukemia. Blood, 99 (8), 2985-2991. 416. Ohashi, E., Inoue, K., Kagechika, H., Hong, S.H., Nakagawa, T., Takahashi, T., Mochizuki, M., Nishimura, R. and Sasaki, N. (2002), Effect of natural and synthetic retinoids on the

×