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Update H7N9 AI outbreak in China, ECDC, April 10, 2013

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On 31 March 2013, the Chinese health authorities announced that they identified a novel influenza A(H7N9) virus in three seriously ill patients. As of 9 April 2013, 26 human cases of infection with influenza A(H7N9) virus have been reported in four provinces of China: Shanghai (13), Jiangsu (8), Zhejiang (3) and Anhui (2). Of these patients, 8 people have died, 15 are severe cases and 3 are mild cases. No epidemiological link has been identified among cases. The source of these infections and the mode of transmission are yet to be determined. This is the first time that human infection with influenza A(H7N9) virus has been identified. No vaccine is currently available for this subtype of the influenza virus. Preliminary test results suggest that the virus is susceptible to the neuraminidase inhibitors (oseltamivir and zanamivir).

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Update H7N9 AI outbreak in China, ECDC, April 10, 2013

  1. 1. http://www.ecdc.europa.eu/en/press/news ECDC Portal > English > Media Centre > NewsEpidemiological update of 10 April: novel influenza A virus A(H7N9) inChina10 Apr 2013On 31 March 2013, the Chinese health authorities announced that they identified a novel influenza A(H7N9) virus in three ECDCseriously ill patients.As of 9 April 2013, 26 human cases of infection with influenza A(H7N9) virus have been reported in four provinces of China:Shanghai (13), Jiangsu (8), Zhejiang (3) and Anhui (2). Of these patients, 8 people have died, 15 are severe cases and 3 are mildcases. No epidemiological link has been identified among cases.The source of these infections and the mode of transmission are yet to be determined. This is the first time that human infectionwith influenza A(H7N9) virus has been identified.No vaccine is currently available for this subtype of the influenza virus. Preliminary test results suggest that the virus is susceptibleto the neuraminidase inhibitors (oseltamivir and zanamivir).At this time, there is no evidence of on-going human-to-human transmission. More sporadic cases are expected to be reported.The risk of disease spread to Europe is considered low, although individual cases coming from China cannot be ruled out.ECDC is working closely with WHO and the European Commission and will continue to monitor the situation.ECDC agrees with the position of WHO and other Centres for Disease Control (the United States and Chinese CDC) that there is noneed to change travel plans for persons going to or coming from China because of the recent appearance of a novel avianHowever, ECDC is repeating its standing advice to European citizens living in or visiting China that because of the presence of thenovel influenza viruses, other avian influenza and zoonotic infections in live bird and animal markets (so called wet markets ) inChina and other countries in Asia should avoid visiting these markets. Direct contact with bird and animal faeces, untreated birdfeathers and other animal and bird waste should also be avoided. In addition, basic rules of hand hygiene should be followedincluding regular hand-washing and use of alcohol-based hand rubs. This is the same advice ECDC has had in place since 2006.This epidemiological update does not change the conclusions and recommendations of ECDC s Rapid Risk Assessment of 2 April2013.Figure 1: Distribution of influenza A(H7N9) cases by date of onset of symptoms, age, gender, status and provincein China, as of 9 April 2013 (n=26).Date of Age Sex Status Severity Provinceonset 19/02/2013 87 M dead severe Shanghai 27/02/2013 27 M dead severe Shanghai 07/03/2013 38 M dead severe Zhejiang 15/03/2013 35 F alive severe Anhui 19/03/2013 45 F alive severe Jiangsu 19/03/2013 48 F alive severe Jiangsu 20/03/2013 83 M dead severe Jiangsu 20/03/2013 61 F alive severe Jiangsu 21/03/2013 32 F alive severe Jiangsu 21/03/2013 79 M alive severe Jiangsu 22/03/2013 67 F alive severe Shanghai 25/03/2013 67 M alive severe Zhejiang 25/03/2013 59 M alive severe Shanghai 27/03/2013 52 F dead severe Shanghai 28/03/2013 48 M dead severe Shanghai 28/03/2013 74 M alive severe Shanghai 28/03/2013 55 M alive severe Anhui 28/03/2013 85 M alive severe Jiangsu 29/03/2013 64 M dead severe Zhejiang 29/03/2013 66 M alive mild Shanghai 29/03/2013 67 M alive mild Shanghai 30/03/2013 25 F alive severe Jiangsu 31/03/2013 4 M alive mild Shanghai 01/04/2013 64 M dead severe Shanghai
  2. 2. 01/04/2013 62 M alive severe Shanghai 01/04/2013 77 M alive severe ShanghaiFigure 2: Distribution of influenza A(H7N9) cases in China by week of onset of symptoms, as of 9 April 2013 (n=26).February to 9 April 2013.Read more: ECDC Rapid Risk Assessment Severe respiratory disease associated with a novel influenza A virus, A(H7N9) China, 2 April 2013 Epidemiological update 9 April 2013: Novel influenza A virus A(H7N9) in China Epidemiological update 5 April 2013: Seven new confirmed cases of novel influenza A virus, A (H7N9) in China Epidemiological update 3 April 2013: Six new confirmed cases of novel influenza A virus, A (H7N9) in China
  3. 3. External links: WHO: question and answers on human infection with influenza A(H7N9) virus, China (updated 5 April 2013) Chinese Center for Disease Control and Prevention: question and answers about human infection with A(H7N9) avian influenza virus (published 31 March 2013) Share European Center for Disease Prevention and Control (ECDC) 2005-2013http://www.ecdc.europa.eu

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