Introduction to histology

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Introduction to histology

  1. 1. Introduction to histology C. Jayawardena, Basic Sciences, 08/09/2010
  2. 2. I want you to understand ....I want you to understand ....  What is histology?  Why do we learn histology?  What is the structural organization of the body?  What do we learn in histology?  How are we tested for histology?  How do we learn histology?  Microscopes  References
  3. 3. Histology/ Microscopic anatomyHistology/ Microscopic anatomy  Gross anatomy  Macroscopic anatomy  Developmental anatomy  Clinical anatomy  Surgical anatomy  Pathological anatomy
  4. 4. Why do you learn histologyWhy do you learn histology
  5. 5. The Hierarchy of Structural OrganizationThe Hierarchy of Structural Organization C r e a t u r e Atoms Organelles Epithelium Connective tissue Muscles Nerves Bones Epithelium Connective tissue Muscles Nerves Bones Heart Lungs Liver Stomach Skin Heart Lungs Liver Stomach Skin CVS RS GIS GUS NS IS CVS RS GIS GUS NS IS
  6. 6. The Hierarchy of Structural OrganizationThe Hierarchy of Structural Organization A group of cells performing a common function A group of cells performing a common function A discrete structure made up of more than one tissue A discrete structure made up of more than one tissue Organs working together for a common purpose Organs working together for a common purpose Cells and their functional subunits Cells and their functional subunits MoleculesMolecules Copyright @ Perason Education
  7. 7. Normal structure Normal functions Healthy life
  8. 8. Abnormal structure No functions Diseased
  9. 9. To Objectives To understand  How cells and tissues are arranged in the normal organ system of the body, and  How these cells and tissues are specialized to perform the functions (structure-function relationship) most effectively. Why do you learn histologyWhy do you learn histology
  10. 10. What do you learn in histologyWhat do you learn in histology
  11. 11. Learn the (microscopic) structure whileLearn the (microscopic) structure while correlating the structure with functionscorrelating the structure with functions Physiological Biochemical Pathological / diseased Treatment Prevention
  12. 12. How are you tested for histologyHow are you tested for histology  Theory - o MCQ o SAQ  Practical – o Spots (OSPE)
  13. 13. How are you tested for histologyHow are you tested for histology BS 1103 – Tissues of the body BS 1105 –Teeth and supporting BS 1106 – Cardiovascular BS 1107 – Respiratory BS 1108 – Gastrointestinal --- 11 / 18
  14. 14. 1.1 Identify precisely 1.2 Give named example for 1.1 in the body 1.3 Identify the structure indicated by the pointer 1.4 Give two reasons for your answer in 1.3
  15. 15. How do you learn histologyHow do you learn histology
  16. 16. How do you learn histologyHow do you learn histology  Practical  Come up with idea what you are looking for today  e.g What do you expect to see in the stratified squamous keratinizing epithelium  See those features in the sections by your-self  Find answers for the questions  Actively involve in the discussion
  17. 17. http://www.lab.anhb.uwa.edu.au/mb140/
  18. 18. Practical Examination  What do you expect to see in the particular tissue or organ (Preparation)  See those features in the sections by your-self (Practical)  How do they appear  Recall  See features seen in the section  From the features, make a identification
  19. 19. MicroscopesMicroscopes  Light microscopy  Polarized microscopy  Confocal microscopy  Fluorescence microscopy  Electron microscopy  TEM – Transmitted EM  SEM – Scanning EM
  20. 20. Light microscopyLight microscopy Gartner and Hiatt. Color Textbook of Histology. 1997. Maximal resolving power: (The smallest distance between 2 points at which they can be seen as separate spots) LM; 0.2µm
  21. 21. Electron microscopyElectron microscopy Gartner and Hiatt. Color Textbook of Histology. 1997. Figure 1.1.
  22. 22. TEM LMTEM LM Gartner and Hiatt. Color Textbook of Histology. 1997. Figure 1.1.
  23. 23. ReferencesReferences http://www.lab.anhb.uwa.edu.au/mb140/

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