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Graham Hughes - Beta Technology - FP 7 Call Presentation


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Graham Hughes - Beta Technology - FP 7 Call Presentation

  1. 1. FP7 2012 Health Call Overview Graham Hughes, FP7UK NCP for Health (Industry)
  2. 2. <ul><li>“ FP7 work programmes will “ continue to secure world excellence in basic research ” through large scale collaborative research efforts </li></ul><ul><li>JM Barroso 2009 </li></ul>
  3. 3. FP7 - €53 billion spend 2007 - 2013
  4. 4. Cooperation Theme
  5. 5. Cooperation Theme Basics <ul><li>Top down process, yearly call for proposals based around specific topic areas </li></ul><ul><li>Projects performed by consortia of academic/industry/ public sector participants </li></ul><ul><li>Matched funding (EU contributes to total cost of project) </li></ul><ul><li>Participants sign legal contract with the EU </li></ul>
  6. 6. <ul><li>Three Major Objectives </li></ul><ul><li>Improve the health of European citizens </li></ul><ul><li>Boost the competitiveness of health related industries </li></ul><ul><li>Address global health issues </li></ul><ul><li>Also seeking to implement research objectives that help to realise the aims of the Innovation Union (Europe 2020) flagship initiative . </li></ul>Health Theme Objectives
  7. 7. The Health Theme: Structure Activity 1: Biotechnology, generic tools & technologies for health Activity 2: Translating research for human health Activity 3: Optimising the delivery of health care cross-cutting issues: international cooperation, SMEs, child health, ageing populations, gender -related health issues Activity 4: Support actions & response to policy needs The Innovative Medicines Initiative
  8. 8. Health Theme Funding 2007 - 2013 Year Total Funding Projects Funded 2007 € 641 million 153 2008 € 577 million 172 2009 € 611 million 105 2010 € 621 million 131 2011 € 650 million ~126 2012 € 620 million ? 2013 € 780 million ?
  9. 9. UK Performance (Health Theme) Health Funding totals 2007 -2009 – All Participations
  10. 10. UK FP7 Health Theme in Numbers* Submissions with UK partners = 3264* Successful projects with UK partners = 859 UK coordinated submissions = 383 93 projects coordinated by UK partners *2007 – 2009 data – from GAs and participants database (released on 1 May 2010 - data cut-off date 25 March 2010 52 UK SMEs in active FP7 projects (plus 17 new 2010)
  11. 11. SME Participation EU target of 15% funding to SME partners
  12. 12. <ul><li>Access significant research funding </li></ul><ul><li>75% RTD costs and 100% management and training costs </li></ul><ul><li>EU contribution between €2 and 12 million </li></ul><ul><li>Overhead rate for HEIs and SMEs = 60% </li></ul><ul><li>Strengthening Research Capabilities </li></ul><ul><li>Increased collaboration between basic and clinical researchers, regulatory bodies and patient groups </li></ul><ul><li>Access to new networks and contacts </li></ul><ul><li>develop new business contacts from the linkages formed in a consortium </li></ul><ul><li>Access to IP and facilities otherwise unavailable </li></ul><ul><li>Elevated Profile </li></ul><ul><li>Publications, CORDIS </li></ul>Collaborative Research: Why?
  13. 13. Collaborative Research: Who? <ul><li>Countries </li></ul><ul><li>EU Member States – broadest rights and access </li></ul><ul><li>Associated Countries – e.g. Iceland, Norway, Turkey, Israel </li></ul><ul><li>International Cooperation Partner Countries (ICPC) – e.g. Russia, Central Asian, Balkan, North African countries </li></ul><ul><li>Industrialised high-income countries (e.g Australia, Korea, Japan) – self financing. USA has reciprocal arrangement </li></ul><ul><li>Co-operation with “third countries” explicitly encouraged in FP7 </li></ul><ul><li>Organisations </li></ul><ul><li>research groups at universities or research institutes </li></ul><ul><li>innovative companies (SMEs and larger) </li></ul><ul><li>public or governmental administration (eg NHS trusts) </li></ul><ul><li>Charities and other not for profit organisations </li></ul>
  14. 14. <ul><li>Build consortium : </li></ul><ul><ul><li>3 legal entities from minimum of 3 EU Member states or Associated Countries </li></ul></ul><ul><ul><li>Other partners added per requirements of project/partner mix </li></ul></ul><ul><ul><li>Some other special eligibility criteria may apply – read call document carefully </li></ul></ul><ul><li>Match project with the topic </li></ul><ul><ul><li>Seek advice if not sure </li></ul></ul><ul><ul><li>Funding level is indicative of project scope </li></ul></ul><ul><ul><li>Pay attention to expected outcome – European scope </li></ul></ul><ul><li>Follow rules for submission (EPSS) </li></ul>Collaborative Research: How?
  15. 15. WP First Draft Open day (Brussels) 09 June 2011 Call published Stage 1 Deadline NCP Roadshow Evaluation results Evaluation PC Meetings Collaborative Research: When?
  16. 16. Framework Programme 7 Support and Further Information Graham Hughes, FP7UK NCP for Health (Industry)
  17. 17. Initial Considerations <ul><li>Are you ready for participation? </li></ul><ul><ul><li>Does it fit your aspirations/business plan </li></ul></ul><ul><ul><li>Collaborative projects mean working alongside international partners. </li></ul></ul><ul><ul><ul><li>Does this suit you way of working? </li></ul></ul></ul><ul><ul><ul><li>Can you pull together or find a consortium? </li></ul></ul></ul><ul><ul><li>Funding is highly competitive, prepare to be disappointed </li></ul></ul><ul><ul><li>Do you want to lead a project? (Time/resource) </li></ul></ul><ul><ul><li>Is the level of funding appropriate? </li></ul></ul><ul><ul><li>Can you wait 1 year for the money? </li></ul></ul>
  18. 18. Key Tips <ul><li>Competition is fierce – must be well over the threshold to succeed </li></ul><ul><li>Remember the European aspect </li></ul><ul><li>Read the call carefully – seek 2 nd and 3 rd opinions on topic fit </li></ul><ul><li>Write simply and clearly – don’t assume expert knowledge </li></ul><ul><li>Make time to do a good job – avoid last minute submissions </li></ul><ul><li>Seek help early on </li></ul>
  19. 19. Support and Further Information
  20. 20. <ul><li>Informing and Awareness Raising </li></ul><ul><ul><li>Call documents and supporting information </li></ul></ul><ul><ul><li>Website and printed newsletters, e-bulletins </li></ul></ul><ul><ul><li>Promotional activities – info days, seminars, </li></ul></ul><ul><ul><li>Signposting – other themes + funding schemes </li></ul></ul><ul><li>Advising and Training </li></ul><ul><ul><li>Helpline – e-mail and telephone enquiries </li></ul></ul><ul><ul><li>Partner search </li></ul></ul><ul><ul><li>Direct support </li></ul></ul><ul><li>Feedback and Signposting </li></ul><ul><ul><li>Problems or difficulties during implementation or participation </li></ul></ul><ul><ul><li>Direct contact with EU Scientific Officers </li></ul></ul><ul><ul><li>Identifying and communicating other areas of support and funding </li></ul></ul>NCP Support All advice is impartial, confidential and free
  21. 21. Support and Further Information <ul><li>Website </li></ul><ul><li>E mail [email_address] </li></ul><ul><li>Phone 01302 322633 </li></ul><ul><li>Mobile 07775 584028 </li></ul><ul><li>Alternative </li></ul><ul><li>[email_address] </li></ul><ul><li>+44 (0)20 7395 2205 </li></ul>
  22. 22. Framework Programme 7 2012 Call Information Graham Hughes, FP7UK NCP for Health (Industry)
  23. 23. 2012 Call – Context <ul><li>Innovation Union </li></ul><ul><li>research and innovation are key drivers of competitiveness, jobs, sustainable growth and social progress. </li></ul><ul><li>More topics targeting knowledge generation to deliver innovative products, processes and services. </li></ul><ul><li>Challenge led programme focusing on specific issues </li></ul><ul><li>More emphasis on exploitation issues such as dissemination, IP protection and knowledge generation. </li></ul>
  24. 24. 2012 Call – Innovation Driven <ul><li>Challenge driven – fewer areas open, multiple projects in each area. (36 topics total) </li></ul><ul><ul><li>Primary focus is European Innovation Partnership initiative on active and healthy ageing </li></ul></ul><ul><ul><li>Aim to mobilise critical mass of resources and implement coherent set of actions </li></ul></ul><ul><ul><li>Interlinked topics to bring in wide range of inputs </li></ul></ul><ul><li>Balance upstream research and activities closer to market to achieve short and medium-term outcomes </li></ul><ul><ul><li>focus on medical technologies </li></ul></ul><ul><ul><li>address the socio-economic challenge of innovation </li></ul></ul>
  25. 25. 2012 Call – Closed Areas <ul><li>1.1 High Throughput Research </li></ul><ul><li>1.3 Suitability, Safety and Efficacy of Therapies* </li></ul><ul><ul><li>2.2.1 Brain and Brain Related Diseases </li></ul></ul><ul><ul><li>2.3.1 Anti Microbial Drug Resistance </li></ul></ul><ul><ul><li>2.3.3 Potentially New and Re-emerging Epidemics </li></ul></ul><ul><ul><li>2.3.4 Neglected Infectious Diseases* </li></ul></ul><ul><ul><li>2.4.1 Cancer </li></ul></ul><ul><ul><li>2.4.2 Cardiovascular Disease </li></ul></ul><ul><li>3.1 Translating the Results of Clinical Research Outcome </li></ul><ul><li>3.3 Health Promotion and Prevention </li></ul><ul><li>4.2 Responding to EU Policy Needs </li></ul>
  26. 26. 2012 Call Overview <ul><li>SME Focus – many SME targeted topics and new SME Call </li></ul><ul><li>Active and Healthy Ageing – 9 coordinated topics </li></ul><ul><li>Medical Technologies – feature highly (related to SME focus) </li></ul><ul><li>Other areas of focus: </li></ul><ul><ul><ul><li>Rare Diseases </li></ul></ul></ul><ul><ul><ul><li>Clinical Trials </li></ul></ul></ul><ul><ul><ul><li>Personalised and Regenerative Medicine (inc transplantation) </li></ul></ul></ul><ul><ul><ul><li>Systems Biology and -omics </li></ul></ul></ul><ul><ul><ul><li>HIV/AIDS, Malaria and TB </li></ul></ul></ul><ul><ul><ul><li>Healthcare delivery </li></ul></ul></ul><ul><ul><ul><li>Coordination and Support Activities </li></ul></ul></ul>
  27. 27. 2012 Call – SME Focused <ul><li>Two stage submission/evaluation </li></ul><ul><li>Several funded proposals per topic </li></ul><ul><li>Technology/Methods based topics </li></ul><ul><li>Open topic descriptions </li></ul><ul><li>Small – medium sized projects </li></ul><ul><ul><li>€ 3m or €6m EC contribution </li></ul></ul><ul><ul><li>2 – 5 year duration </li></ul></ul><ul><li>SME targeted topics </li></ul><ul><ul><li>10 Minimum 30% of EC contribution to SMEs </li></ul></ul><ul><ul><li>6 Minimum 15% of EC contribution to SMEs </li></ul></ul>> 30% >15%
  28. 28. Health Theme Funding 2007 - 2013 Year Total Funding Projects Funded SME Targeted 2 Stage 2007 € 641 million 153 0% 0 2008 € 577 million 172 0% 0 2009 € 611 million 105 0% 0 2010 € 621 million 131 0% 19% 2011 € 650 million ~126 20% 75% 2012 € 620 million ? 53% 100% 2013 € 780 million ? ~ 50% 100%
  29. 29. 2012 Call – Pilot SME Innovation Call <ul><li>3 topics only: </li></ul><ul><ul><li>1,4-2: Medical Technology for transplantation and bioartificial organs </li></ul></ul><ul><ul><li>2.3.0-1: Diagnostics for infectious diseases in humans </li></ul></ul><ul><ul><li>2.4.5-1: Technological approaches to combating sensory impairments </li></ul></ul><ul><li>SMEs have leading role in the project </li></ul><ul><li>>50% EU funding goes to SME partners </li></ul><ul><li># participants limited (3 – 5) </li></ul><ul><li>All partners from EU MS or ACs </li></ul><ul><li>Limits on project duration </li></ul><ul><li>Accelerated evaluation and grant negotiation timeline </li></ul>> 50%
  30. 30. 2012 Call – Research Priorities #1 Ageing <ul><li>Must meet Europe 2020 objectives of active and healthy ageing: </li></ul><ul><ul><li>Healthy, active and independent lives until old age </li></ul></ul><ul><ul><li>Ensure the sustainability and efficiency of social and healthcare systems </li></ul></ul><ul><ul><li>Create a European/Global market for innovative products and services related to healthy and active ageing </li></ul></ul><ul><li>11 Topics in call are linked to EIP initiative </li></ul><ul><li>Cross thematic initiative: ICT,KBBE + SSH </li></ul>EIP
  31. 31. 2012 Call – Research Priorities #2 Medical Technologies <ul><li>Supporting the “innovation” strategy and closer to market approach </li></ul><ul><li>Large overlap with “SME friendly” topics </li></ul><ul><li>9 topics through the work programme </li></ul>Tech
  32. 32. 2012 Call – Research Priorities #3 Clinical Trials <ul><li>Continue the initiative started in the 2011 call for investigator driven clinical trials </li></ul><ul><ul><li>Improve quality of clinical trials data in Europe </li></ul></ul><ul><ul><li>Strengthen CTs in Europe in areas with unmet medical needs </li></ul></ul><ul><li>Funding for Stage II,III or IV clinical trials as RTD activities (i.e. 75% EC contribution). Flexibility w.r.t. duration and participation. </li></ul><ul><li>Involvement of patient groups encouraged </li></ul><ul><li>Outsourcing possible </li></ul><ul><ul><li>Subcontracted third party </li></ul></ul><ul><ul><li>Reimbursement on cost basis </li></ul></ul>Clin
  33. 33. 1.2: Detection, Diagnosis and Monitoring EIP > 30% <ul><li>Support R&D and/or proof of principle of technologies for application in the area of personalised medicines </li></ul><ul><ul><li>Tailored medical interventions </li></ul></ul><ul><ul><li>More effective </li></ul></ul><ul><ul><li>Fewer undesirable side effects </li></ul></ul><ul><li>Technologies should be of use for research, screening, diagnostics and/or guidance on therapeutic interventions </li></ul>1.2.1 Development of technologies with a view to patient group stratification for personalised medicine applications 6,000,000 >1
  34. 34. 1.4: Innovative Therapeutic Approaches and Interventions >15% >15% EIP > 50% > 30% Tech Tech * 1.4-3 requires cooperation with Australia Clin Transplantation topics have not featured highly in FP7 to date 1.4-1 Innovative approaches to solid organ transplantation 6,000,000 >1 1.4-2 Medical technology for the transplantation sector and bioartificial organs 6,000,000 >1 1.4-3* Innovative strategies for translation of stem cell based therapies in regenerative medicine 6,000,000 1 1.4-4 Targeted nucleic acid delivery as an innovative therapeutic or prophylactic approach 6,000,000 >1
  35. 35. 2.1.1: Large Scale Data Gathering >15% EIP > 30% > 30% <ul><li>Objective is to use high-throughput technologies to generate data for elucidating the function of genes and gene products. </li></ul><ul><li>Topics focus on the clinical use of –omics approaches and analysis of their outcomes. </li></ul> Support for international rare disease research 2,000,000 1 Clinical utility of -omics for better diagnosis of rare diseases 12,000,000 2 Databases, biobanks and clinical bio-informatics' hub for rare diseases 12,000,000 1 2.1.1-2 Validation of -omics based biomarkers for diseases affecting the elderly 12,000,000 >1 2.1.1-3 Statistical methods for collection and analysis of -omics data 6,000,000 >1
  36. 36. 2.1.2: Systems Biology <ul><li>medical needs should drive systems biology research </li></ul><ul><li>using systems medicine to improve understanding of disease mechanisms, prognosis and diagnosis of common diseases </li></ul><ul><li>Coordinate European research activities for systems biology applications to medicine </li></ul>> 30% 2.1.2-1 Systems medicine: SME-driven research applying systems biology approaches to address clinical needs 3,000,000 >1 2.1.2-2 Systems medicine: Applying systems biology approaches for understanding common human diseases and their co-morbidities 12,000,000 >1 2.1.2-3 Preparing for the future research and innovation activities in systems medicine 3,000,000 1
  37. 37. 2.2.2: Human Development and Ageing >15% EIP EIP Clin > 30% <ul><li>Focus on use and application of –omics knowledge and tools to gain a clear understanding of the fundamental mechanisms of human ageing </li></ul><ul><li>Clinical trials should compare outcomes of various treatment regimens </li></ul>2.2.2-1 Integrative systems biology and comparative genomics for studying human ageing and most common age-related conditions 6,000,000 >1 2.2.2-2 Investigator-driven clinical trials for optimisation of treatment for elderly patients with multiple diseases 6,000,000 >1
  38. 38. 2.3.0: Cross Cutting > 50% Tech <ul><li>SMEs should take a leading role in 2.3.0-1 </li></ul><ul><li>Project should be < 3 years </li></ul><ul><li>€ 6,000,000 ceiling is max only </li></ul><ul><li>ERA-NET should deepen and extend the coordination of European research in infectious diseases and be complementary to other European activities in this area. </li></ul>2.3.0-1 Diagnostics for infectious diseases in humans 6,000,000 >1 2.3.0-2 ERA-NET on Infectious Diseases 2,000,000 1
  39. 39. 2.3.2: HIV/AIDS Malaria and TB <ul><li>Co-infection and co-morbidity of HIV and other common infectious diseases poorly understood </li></ul><ul><li>Prevention topic is looking for small, rapid projects </li></ul><ul><ul><li>1 – 3 years, €1 – 6 million funding </li></ul></ul><ul><li>Low cost interventions looking for solutions that can be implemented within the project period </li></ul>>15% 2.3.2-1 Co-infection and co-morbidity in HIV/AIDS, malaria, tuberculosis and/or hepatitis 6,000,000 >1 2.3.2-2 Co-morbidity between infectious and non-communicable diseases 6,000,000 >1 2.3.2-3 Prevention and treatment for HIV/AIDS, malaria and tuberculosis 6,000,000 >1 2.3.2-4 Low-cost interventions for disease control in resource poor settings 3,000,000 >1
  40. 40. 2.4.3: Diabetes and Obesity Clin > 30% Tech 2.4.3-1 Innovative approach to manage diabetes 6,000,000 >1 2.4.3-2 Investigator-driven clinical trials for type 1 diabetes research 6,000,000 >1
  41. 41. 2.4.4: Rare Diseases Clin Clin > 30% 2.4.4-1 Preclinical and/or clinical development of substances with a clear potential as orphan drugs 6,000,000 >1 2.4.4-2 Observational trials in rare diseases 3,000,000 >1 2.4.4-3 Best practice and knowledge sharing in the clinical management of rare diseases 2,000,000 1
  42. 42. 2.4.5: Other Chronic Diseases EIP > 50% >15% EIP Tech Tech 2.4.5-1 Technological approaches to to combating sensory impairments 6,000,000 >1 2.4.5-2 Biomarkers and diagnostics for chronic inflammatory diseases of the joints 6,000,000 >1
  43. 43. 2012 Call – Healthcare Delivery <ul><li>Addressing the need for systematic mapping of variations in health care practice and standardisation of health technology assessment </li></ul><ul><li>Various areas of healthcare covered </li></ul><ul><li>EU has strong political stance on healthcare equality </li></ul>EIP EIP Tech 3.2-1 Improving the organisation of health service delivery 3,000,000 >1 3.2-2 New methodologies for health technology assessment 3,000,000 >1 3.2-2 Social Innovation platform for ageing research 6,000,000 1 3.4-1 Health systems/services research in low and middle income countries 6,000,000 >1
  44. 44. 2012 Call – Coordination and Support Actions <ul><li>Various actions to complement research activities, develop infrastructure and determine future activities </li></ul>4.1-1 Network to encourage technology transfer in FP-funded health research (especially in academic and governmental organisations) 2,000,000 1 4.1-2 Training actions linked to intellectual property rights management and technology transfer 2,000,000 1 4.1-3 Support for Presidency events: Organisation of supporting actions and events related to the Presidency of the European Union 100,000 >1 4.1-4 Communicating the benefits of European research to the general public 1,000,000 >1 4.1-5 Preparing for the future for health research and innovation 500,000 >1
  45. 45. <ul><li>09 June 2011: Open Info Day, Brussels </li></ul><ul><li>10 June 2011: Brokerage Event, Brussels </li></ul><ul><li>20 July 2011: Call Opens – EPSS available </li></ul><ul><li>27 Sept 2011: likely Stage 1 deadline (INNOVATION 2) </li></ul><ul><li>04 Oct 2011: likely Stage 1 deadline (INNOVATION 1) </li></ul><ul><li>Dec 2011: Stage 1 notification </li></ul><ul><li>Feb 2012: Stage 2 deadline </li></ul>Key Dates
  46. 46. Other Health Related EU Funding Sources 2011 Nanosciences, Materials and Production NMP NMP.2012.1.2-2: Development and phase-I clinical trials of novel therapeutic nanotechnology-enabled systems for the diagnosis and treatment of atherosclerosis NMP.2012.2.2-1: Biomaterials for improved performance of medical implants Likely timeframe similar to Health call
  47. 47. Other Health Related EU Funding Sources 2011 <ul><li>ICT call </li></ul><ul><li>Virtual Physiological Human </li></ul><ul><li>E-health and data management </li></ul><ul><li>KBBE call </li></ul><ul><li>Research For the Benefit of SMEs </li></ul><ul><li>Call opens July 2011 </li></ul><ul><li>Ambient Assisted Living </li></ul><ul><li>ICT based solutions for Advancement of Older Persons’ Mobility </li></ul><ul><li>Call opened 31 March 2011, deadline 30 June 2011 </li></ul>