Successfully reported this slideshow.
We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. You can change your ad preferences anytime.

Emergency Drugs

Sr.THAVAMANI KANDASAMY
ICU - STAFF NURSE

  • Login to see the comments

Emergency Drugs

  1. 1. EMERGENCY DRUGS AND CALCULATIONS THAVAMANI KANDASAMY ICU - STAFF NURSE
  2. 2. SYSTEMIC CIRCULATION
  3. 3. CHANNELS OF DRUG ADMINISTRATION • ENTERAL ( ORAL,SL,BUCCAL,RECTAL) • PARENTERAL ( IM,IV,IA,SC,ID, INTRATHECAL, INTRA ARTICULAR ) • TOPICAL (EYE,NOSE,EARS,LUNGS,VAGINA,URETHRA,COLON)
  4. 4. DOPAMINE • 1 ampoule= 200mg/5ml • AMOUNT OF DRUG NEEDED per 50 ml infusion solution : • Amount of drug to dilute = Body weight x 3 • Ex. 70 kg x 3= 210 mg Amount of drug = 210mg x5ml = 5.25ml 2oomg • PREPARATION : 44.75 ml NSS +5.25ml drug = 50ml • 1ml = 210mg x 1000 = 4200mcg • 50ml • RATE OF INFUSION : mcg x body weight x 60 min drug concentration • Example : 5 mcg x 70 x 60 = 5 ml/hr 4,200 mcg
  5. 5. DOBUTAMINE • 1 ampule= 250mg/5mL • AMOUNT OF DRUG NEEDED in 50 ml solution • Amount of drug = body weightx 3 • Ex. 70 kg x 3= 210 mg • Amount of drug in ml = 210mg x5ml = 4.2ml 250MG • PREPARATION : 45.8 ml NSS + 4.2ml drug = 50 ml • Rate of Infusion : mcg x body weight x 60 min Drug concentration • Example: 4 mcg x 70 kg x 60 = 4ml/hr 4200 mcg/ml
  6. 6. LEVOPHED • 1 ampoule 3mg / 3ml • PREPARATION : 3 mg +47 ml D5W = 50ml • DRUG CONCENTRATION : 3mg/50ml=0.06mg/1ml • 0.06mg x 1000mcg =60mcg/ml • Rate of Infusion : Desired Dose x 60 min 60 mcg • Example : 2 mcg x 60 min = 2 ml / hr 60 mcg
  7. 7. NITROGLYCERINE • 1 ampule= 50 mg ( 10 ml) • PREPARATION: 40 ml NSS + 10 ml NTG • DRUG CONCENTRATION : 50 mg/ 50 ml = 1mg/1ml • 1mg x 1000 = 1,000mcg /1ml • Rate of Infusion : Desired Dose x 60 Drug Concentration • Example : 5 mcg x 60 min = 0.3 ml/hr 1000 mcg
  8. 8. ADRENALINE • 1 ampoule = 1ml/1mg • PREPARATION: 12 ml of Adrenaline + 38 ml D5W = 50 ml • DRUG CONCENTRATION = 12 mg/ 50 ml=0.24mg • 0.24mg x1000= 240mcg /ml • Rate of Infusion: Desired dose x 60 = ml /hr 240mcg • Example : 2mcg x 60 min = 0.5 ml/hr 240mcg
  9. 9. INSULIN • PREPARATION: 49.5 ml NSS + 50 units (0.5 ml R.I ) • Rate of Infusion : Desired Dose x Quantity 50 units • Example : 3 units x 50 ml = 3 ml / hr 50 units
  10. 10. HEPARIN • 1 ampule : 25,000 IU / 5ml • PREPARATION : 45 ml NSS + 25,000 (5 ml) Heparin • Rate of Infusion : Desired dose x Quantity Drug Concentration • Example : 100 units x 50 = 0.2 ml/hr 25, 000 units
  11. 11. LASIX • 1 ampule = 20mg (2 ml) • Drug Concentration : 10 ampule = 200mg (20ml) • PREPARATION: 20 ml Lasix + 20 ml NSS • 40 ml = 200 mg • 1 ml = 5mg • Rate of Infusion : Desire dose x quantity = ml/hr Drug concentration • Example : 10 mg/hr x 40 ml = 2 ml /hr 200 mg
  12. 12. PHENYTOIN • 1 ampoule : 250 mg / 5 ml • LOADING DOSE: 15 mg/kg at a rate not greater than 50 mg/min for 20 – 30 mins. • MAINTENENCE DOSE: followed by 100 mg every 6- 8 hours PROPHYLAXIS: 200-600 mg/day PO/IV • ANTIARRYTHMIC : 10 mg IV every 15 minutes until arrhythmia stops
  13. 13. AMIODARONE • 1 ampoule = 150 mg (3ml) • LOADING DOSE : 1 ampule ( 150 mg /3 ml) + 12 ml D5W • A .MAINTANENCE DOSE : 360 mg in 6 hours • 360 mg x 3 ml = 7.2 ml 150 mg • 7.2 ml ( amiodarone) + 42.8 ml D5%W = 50 ml = 8.3 ml/hr B. 540 mg in 18 hours • 540 mg x 3 ml = 10.8 ml 150 mg • 10.8 ml ( amiodarone ) + 39.2 ml D5%W= 2.7ML /hr
  14. 14. OMEPRAZOLE • 1 vial = 40 mg • PREPARATION : 5 vial (200mg) Omeprazole + 50 ml NS • 50 ml = 200mg • 1 ml = 4 mg • Rate of Infusion : Desired dose x Quantity = ml/hr Drug Concentration • Example : 8 mg x 50 ml = 2 ml /hr 200mg •
  15. 15. LABETALOL • 1 ampule(20 ml) = 100 mg • Preparation : 20 ml Labetalol + 30 ml NSS • Drug Concentration : 1 ml = 2 mg • Rate of Infusion : Desired Dose x Quantity Drug concentration • Example : 5 mg x 50 = 2.5 ml / hr 100 mg
  16. 16. HYDRALAZINE • 1 ampoule = 20 mg • PREPARATION: 20 mg dilute in 1 ml water of inj. • LOADING DOSE: 10-20 mg over 3-5 minutes, further dilute with 10 ml NS over 3-5 mins. • then repeat after 20-30 minutes. • INFUSION: Reconstitute 3 ampoules (60 mg) Hydralazine with 1 ml water of inj. Each. • Make up to 60 ml with NSS. • Drug Concentration: 1 ml : 1 mg • Note : Give rate between 2 and 15 mg / hr depending on BP and pulse.
  17. 17. VASOPRESSIN • 1 ampoule = 20 units / 1 ml • USUAL DOSE: 0.01 to 0.03 units/ minute • PREPARATION : 20 units in 50 ml NSS • DRUG CONCENTRATION: 20units / 50ml = 0.4units / ml • Rate of Infusion: Desired Dose x 60 Drug Concentration • Example : 0.01 units/min x 60 = 1.5 ml/hr 0.4 units / ml
  18. 18. PHENYLEPHRINE • 1 ampoule: 10 mg / 1ml • PREPARATION: 10 mg in 250 ml NSS • 1ml = 40 mcg/min • Rate of Infusion : Desired Dose x 60 = ml/hr 40 mcg/ml • Example : 1 mcg /min x 60 = 1.5 ml/hr 40 mcg/ min
  19. 19. PROPOFOL • INFUSION: 1 ampoule: 200 mg = 20 ml • PREPARATION : 500 mg = 50 ml without dilution • DRUG CONCENTRATION: 1 ml = 10 mg • Rate of Infusion : Desired Dose x quantity Drug Concentration • Example : 10 mg x 50ml = 1ml/hr 500mg
  20. 20. SANDOSTATIN ( OCTREOTIDE) • 1 ampoule : 100 mcg/ml • 3 ampules (300 mcg /3 ml) + 27 ml NSS = 30 ml • Drug Concentration: 30 ml = 300 mcg • 1 ml = 10 mcg • NOTE : 25 MCG BOLUS FOLLOWED BY 25 – 50 MCG / HR
  21. 21. ATRACURIUM • 1 ampule : 25 mg ( 2.5 ml) • PREPARATION : 4 ampule (100mg) + 40 ml NSS • DRUG CONCENTRATION: 100 mg /50ml • Rate of Infusion: Desired Dose x 50 ml Drug Concentration • Example : 5 mg x 50 ml = 5 ml / hr 100mg
  22. 22. FENTANYL • INFUSION:1 ampoule = 500 mcg (10 ml) • PREPRATION : 10 ml Fentanyl + 40 ml NSS • Drug Concentration : 50 ml = 500 mcg • 1 ml = 10 mcg • Rate of Infusion : Desired Dose x Quantity Drug Concentration • Example : 25 mcg x 50 ml = 2.5 ml 500mcg
  23. 23. DORMICUM( MIDAZOLAM) • 1 ampoule = 15 mg (3ml) • PREPARATION: 45 mg ampule (9 ml) + 36 ml NSS • Drug Concentration : 45mg /45ml =1mg/1ml • Rate of Infusion : Desired Dose x Quantity Drug Concentration • Example : 2mg x 45 ml = 2ml / hr 45mg

×