Chromosomes, chromatin and cellcycle<br />Catalina Urango Giraldo<br />Medicine Student<br />3rd Semester<br />
Cancer!!<br />alterations<br />Has control points<br />CELL CYCLE<br />Celldivision<br />DNA ispackaged in theform of<br /...
Scientistsfind “brake-override” proteinsthatenabledevelopment of somecancers<br />Biology & Nature<br />July 7/2011<br />
<ul><li>CKs 1 and CKs 2 are twoproteinsknownforbeingoverexpressed in cancer.</li></ul>CancerCKsoverexpression<br />cancerc...
Observation<br />In my opinion, every research that leads medicine to a better understanding of how cancer “operates” in t...
Research links telomerelengthtoemphysemarisk.<br />Health & Medicine<br />July 15/2011<br />
Thetelomeres are thebody’sowncelullarclocks.<br />  In thisstudy, itwasfound a closerelationshipbetweentelomerelength and ...
byCelldivision (makesthemshorter)</li></li></ul><li>Gettingresults<br />-> short telomere<br />-> longtelomere<br />↖<br /...
the results obtained in this research indicates that short telomeres plus cigarette smoke might accelerates aging in the l...
Observation<br />in my opinion, it is important to keep searching about diseases that can be related to the telomere lengt...
MedicalUtility<br />
Medicalutility<br />Thankstothisresearches, medicine can advance, and nowwiththediscover of CKs role in cancer, thereis a ...
Medicalutility<br />Withthediscovering of the link between short telomere and emphysema, new research can establishmethods...
Medicalutility<br />Withallthisresearch, medicine isgettingclosetoguaranteemore efficientmethodsforcuringcancer and preser...
Bibliography<br />- Scientistsfind “brake-override” proteinsthatenabledevelopment of somecancers. URL: http://esciencenews...
Folding: chromosomes, chromatine and cell cycle
Folding: chromosomes, chromatine and cell cycle
Folding: chromosomes, chromatine and cell cycle
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Folding: chromosomes, chromatine and cell cycle

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Folding: chromosomes, chromatine and cell cycle

  1. 1. Chromosomes, chromatin and cellcycle<br />Catalina Urango Giraldo<br />Medicine Student<br />3rd Semester<br />
  2. 2.
  3. 3.
  4. 4. Cancer!!<br />alterations<br />Has control points<br />CELL CYCLE<br />Celldivision<br />DNA ispackaged in theform of<br />2 daughtercells<br />guarantee<br />Normal cells and growth<br />chromosomes<br />Ending<br />sequences<br />telomeres<br />determine<br />Lifeexpectancy<br />Reproductivecapacity of cells<br />Dependingonitslength<br />
  5. 5. Scientistsfind “brake-override” proteinsthatenabledevelopment of somecancers<br />Biology & Nature<br />July 7/2011<br />
  6. 6. <ul><li>CKs 1 and CKs 2 are twoproteinsknownforbeingoverexpressed in cancer.</li></ul>CancerCKsoverexpression<br />cancercells<br />uncontrolledgrowth<br />by<br />a checkpoint<br />nullifyingeffect<br />RESEARCH DISCOVERY<br /><ul><li>In thepresentstudy, thesearchteamfoundthat a CKsoverexpressionallowscancercellstokeepdividing.</li></li></ul><li>When a mutation induces anuncontrolled and fastcellgrowth, thecellsends a break signal.<br /><ul><li>The break signal, produced as a checkpoint response, stopscellcycle, and DNA’sreplicationwon’tgoeson.</li></li></ul><li>BUT…!!<br />Whenit comes tocancer, itwasfoundthat:<br />Thanksto a CKsoverexpression, thecancercellswill ignore the S-phasecheckpoint response, passoverit and keepdividing.<br />
  7. 7. Observation<br />In my opinion, every research that leads medicine to a better understanding of how cancer “operates” in the body, represents one more step to find a treatment.<br />
  8. 8. Research links telomerelengthtoemphysemarisk.<br />Health & Medicine<br />July 15/2011<br />
  9. 9. Thetelomeres are thebody’sowncelullarclocks.<br /> In thisstudy, itwasfound a closerelationshipbetweentelomerelength and a increasesusceptibilitytodevelopemphysema. <br />Itslengthis determine :<br /><ul><li>Genetically
  10. 10. byCelldivision (makesthemshorter)</li></li></ul><li>Gettingresults<br />-> short telomere<br />-> longtelomere<br />↖<br />↖<br />DidNOTdeveloplungdisease<br />Developedemphysema<br />
  11. 11. the results obtained in this research indicates that short telomeres plus cigarette smoke might accelerates aging in the lung in some individuals.<br />Short telomere<br />Cells can notlonger divide<br />Increasesrisktodevelopemphysema<br />lungdamage<br />
  12. 12. Observation<br />in my opinion, it is important to keep searching about diseases that can be related to the telomere length, so it can be determine how the susceptibility to a disease can be affected and what can be done to improve health with age. <br />
  13. 13. MedicalUtility<br />
  14. 14. Medicalutility<br />Thankstothisresearches, medicine can advance, and nowwiththediscover of CKs role in cancer, thereis a new target forcancertreatment.<br />
  15. 15. Medicalutility<br />Withthediscovering of the link between short telomere and emphysema, new research can establishmethodsto preserve someorgansfunctionwithage.<br />
  16. 16. Medicalutility<br />Withallthisresearch, medicine isgettingclosetoguaranteemore efficientmethodsforcuringcancer and preserve lifewiththeage.<br />
  17. 17. Bibliography<br />- Scientistsfind “brake-override” proteinsthatenabledevelopment of somecancers. URL: http://esciencenews.com/articles/2011/07/07/scientists.find.brake.override.proteins.enable.development.some.cancers<br /> (Biology & Nature)<br />- Research links telomerelengthtoemphysemarisk. URL: http://esciencenews.com/articles/2011/07/15/research.links.telomere.length.emphysema.risk<br /> (Health & Medicine)<br /> <br />- MARTINEZ S., Lina Maria. Biologia Molecular. 6.ed.Medellin:UPB.Fac.de Medicina,2011.52 p. <br />

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