Hematology Clinic 13123 East 16th Ave, B115 Aurora, CO 80045 Office: 720 .777.6578 After hours: 720.777.6740 Generic name: enoxaparin (ee-nox-a-PAR-in) Brand name: Lovenox®[You= you and/or your child]What Is Enoxaparin?Enoxaparin is an anticoagulant medicine (“anti” means against and “coagulant” means to thicken or clot)that helps to reduce the chance of clots from forming in the blood. Enoxaparin is commonly used toprevent and/or treat blood clots.How Does Enoxaparin Work?Enoxaparin blocks a certain clotting factor in your body (called activated factor ten or factor Xa) to reduceyour body’s ability to make blood clots.What Are Possible Side Effects of Enoxaparin? Side effects of enoxaparin may happen and may include bleeding. Common/minor side effects (if any of the following become worrisome, you may contact the clinic): o irritation at the injection site o bruising more easily or around injection sites o gum bleeding while brushing your teeth o occasional nose bleeds that stop within a few minutes o bleeding after a minor cut that stops within a few minutes o small lumps (also called hematoma) under your skin or around injections sites o Women: menstrual bleeding (“period”) that is a little heavier than usual Major/serious side effects- Call the clinic or GO to the Emergency Room if you experience any of the following: o excessive or unusual bleeding o painful swelling of an arm or leg from any part on your body o chest pain or painful breathing o dark brown or red urine o weakness on one side of the body o red or black (tar-colored) stools o sudden difficulty speaking o vomiting blood o sudden changes in vision o excessive bruising o unusually severe or prolonged headache o severe stomach pain o yellowing of the skin or eyes o dizziness
How Do I Take Enoxaparin? The amount of enoxaparin each person needs is different. Your dose is based on your weight and a blood test called anti-Xa or heptest that measures the effect of enoxaparin in your blood. The amount of medication you take may change based on this blood test so it is important to take the dose as directed by The Children’s Hematology Clinic. Injections should be given every twelve hours at the same time every day or as directed by your health care provider. Enoxaparin is given under the fatty part of the skin called the subcutaneous tissue. The best sites for injections are the U-shaped area around the belly button, the upper outer side of the thighs, or buttocks. Use a different site each time you give yourself a shot. It is important to apply a minimum of 5 minutes of pressure to the injection site to help reduce bruising and hematomas (small lumps under your skin or around the injections site). Remember to wash your hands, clean the injection site with alcohol prior to each injection, and use a new needle and syringe each time you inject your medicine. Throw away needles in needle/sharp disposal box and return box to healthcare provider when full.What Should I Do If I Miss A Dose? You should try not to skip any doses of enoxaparin since this can affect the medicine’s ability to prevent blood clots. o If you miss a single dose of enoxaparin take the dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and return to your regular schedule. o If you forget more than one dose of enoxaparin, contact your health care provider immediately. DO NOT use another dose to “catch up”.Enoxaparin & Your Medications (prescription, over-the-counter, herbal/alternative/nutritionalsupplements) Since certain medications increase the risk for bleeding, please make sure to tell any other healthcare providers that you are taking enoxaparin. If you have questions, contact the Hematology Clinic. Avoid other medicines that contain aspirin, ibuprofen (Motrin), or naproxen (Alleve) since they can increase your risk for bleeding, and possibly interfere with the benefits of aspirin. It is okay to use acetaminophen as needed for pain, fever, or headache.
Staying Safe While Using Enoxaparin Always wear a helmet while riding a bike or skateboard, and always wear seatbelts in motor vehicles. This is especially important while taking enoxaparin, since injuries can result in more severe bleeding. Be careful when using sharp objects such as knives, razors, and scissors that could make you bleed. Call us if you are involved in a falls or accidents, especially if you hit your head. Call us even if you feel fine. Inform ALL healthcare providers (physicians, dentists, etc.) that you are taking enoxaparin, especially before undergoing any procedures or surgeries. Notify the clinic a few weeks before undergoing any procedures or surgeries. A written plan for stopping enoxaparin before the procedure/surgery and restarting it afterward will be made by the clinic, and provided to both you and the healthcare provider who will be performing the procedure/surgery.