Processes
in the Nephron
• Filtration
• Reabsorption
• Secretion
Nephron
• 1.25 million nephrons in a kidney
• FILTER blood
Parts of the Nephron
• Glomerulus
– Bed of capillaries
– Receives “DIRTY” blood from the renal
ARTERY
• Bowman’s capsule
–...
Parts of the Nephron
• Renal tubule
– Proximal convoluted tubule
– Loop of Henle
– Distal convoluted tubule
– Walls are PE...
Filtration
• General Definition
– Passing liquid or gas through a filter to
remove impurities
• Nephron
– Small particles ...
Filtration
• Materials that ARE filtered include…
– WATER
– MINERAL SALTS
– Nutrients (Glucose & amino acids)
– NITROGENOU...
Filtration
• Materials that ARE NOT filtered
include…
– Proteins
– Large Cells
– Red Blood Cells
Two pathways
1. Some materials will flow through the
RENAL TUBULE into the
COLLECTING DUCT and be excreted
as URINE.
2. So...
Reabsorption
• Process where a LIQUID is taken back
into a VESSEL
• FILTRATE flows through the RENAL
TUBULE
• Material tha...
Reabsorption
• Materials reabsorbed by…
– ACTIVE TRANSPORT
• NaCl,nutrients (glucose & amino acids)
– PASSIVE TRANSPORT
• ...
Reabsorption
• 75% of reabsorption occurs in the
PROXIMAL CONVOLUTED TUBULE
• Rest of reabsorption occurs in the
LOOP OF H...
Reabsorption
• Concentration gradient formation by
ACTIVE TRANSPORT
– Causes blood in capillaries to become
HYPERTONIC, th...
Secretion
• Release of specific substances from the
BLOOD (capillaries) back into the
FILTRATE (now known as urine) in the...
Secretion
• Occurs mostly in the
DISTAL CONVOLUTED TUBULE
• Some in the
PROXIMAL CONVOLUTED TUBULE
Collecting duct
• Continues to concentrate the urine by
removing water from the urine
Hormones
• Antidiuretic Hormone
Antidurietic Hormone (ADH)
• Regulates WATER conservation
• Increases water absorption by making walls of
the collecting d...
Feeling thirsty?
What’s happening to your ADH levels
(and the concentration of your urine)?
– ADH levels INCREASE
– MORE w...
Had enough water?
• ADH levels DECREASES
• LESS water is retained
• Urine is NOT concentrated
Last stages…
• Urine collects in the COLLECTING DUCTS of
NEPHRONS
• Urine enters the hollow area of the kidney
called the ...
Excretory ppt moodle 2013 2014
Excretory ppt moodle 2013 2014
Excretory ppt moodle 2013 2014
Excretory ppt moodle 2013 2014
Excretory ppt moodle 2013 2014
Excretory ppt moodle 2013 2014
Excretory ppt moodle 2013 2014
Excretory ppt moodle 2013 2014
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Excretory ppt moodle 2013 2014

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Excretory ppt moodle 2013 2014

  1. 1. Processes in the Nephron • Filtration • Reabsorption • Secretion
  2. 2. Nephron • 1.25 million nephrons in a kidney • FILTER blood
  3. 3. Parts of the Nephron • Glomerulus – Bed of capillaries – Receives “DIRTY” blood from the renal ARTERY • Bowman’s capsule – CUP-LIKE structure that surrounds the GLOMERULUS – “Dirty” blood (FILTRATE) is forced here by a FILTRATION process
  4. 4. Parts of the Nephron • Renal tubule – Proximal convoluted tubule – Loop of Henle – Distal convoluted tubule – Walls are PERMEABLE • Collecting duct – SURROUND the renal tubule – Leads to the ureter
  5. 5. Filtration • General Definition – Passing liquid or gas through a filter to remove impurities • Nephron – Small particles in the blood are forced out of the GLOMERULUS into the BOWMAN’S CAPSULE. – This solution is now referred to as the FILTRATE (similar to plasma except that it does not contain protein.)
  6. 6. Filtration • Materials that ARE filtered include… – WATER – MINERAL SALTS – Nutrients (Glucose & amino acids) – NITROGENOUS WASTES
  7. 7. Filtration • Materials that ARE NOT filtered include… – Proteins – Large Cells – Red Blood Cells
  8. 8. Two pathways 1. Some materials will flow through the RENAL TUBULE into the COLLECTING DUCT and be excreted as URINE. 2. Some materials will be REABSORBED into the blood through CAPILLARIES that surround the renal tubule.
  9. 9. Reabsorption • Process where a LIQUID is taken back into a VESSEL • FILTRATE flows through the RENAL TUBULE • Material that the body need is REABSORBED by surrounding CAPILLARIES
  10. 10. Reabsorption • Materials reabsorbed by… – ACTIVE TRANSPORT • NaCl,nutrients (glucose & amino acids) – PASSIVE TRANSPORT • H20 (osmosis)
  11. 11. Reabsorption • 75% of reabsorption occurs in the PROXIMAL CONVOLUTED TUBULE • Rest of reabsorption occurs in the LOOP OF HENLE and the DISTAL CONVOLUTED TUBULE
  12. 12. Reabsorption • Concentration gradient formation by ACTIVE TRANSPORT – Causes blood in capillaries to become HYPERTONIC, therefore WATER follows by simple DIFFUSION, (OSMOSIS).
  13. 13. Secretion • Release of specific substances from the BLOOD (capillaries) back into the FILTRATE (now known as urine) in the renal tubule. – Nitrogenous wastes (passive transport) – Hydrogen ions (active transport) • Adjusts the pH of the filtrate (urine) to about 6. – Potassium ions (active transport)
  14. 14. Secretion • Occurs mostly in the DISTAL CONVOLUTED TUBULE • Some in the PROXIMAL CONVOLUTED TUBULE
  15. 15. Collecting duct • Continues to concentrate the urine by removing water from the urine
  16. 16. Hormones • Antidiuretic Hormone
  17. 17. Antidurietic Hormone (ADH) • Regulates WATER conservation • Increases water absorption by making walls of the collecting ducts MORE PERMEABLE • Regulated by the BRAIN (PITUITARY GLAND)
  18. 18. Feeling thirsty? What’s happening to your ADH levels (and the concentration of your urine)? – ADH levels INCREASE – MORE water is retained – Urine is CONCENTRATED
  19. 19. Had enough water? • ADH levels DECREASES • LESS water is retained • Urine is NOT concentrated
  20. 20. Last stages… • Urine collects in the COLLECTING DUCTS of NEPHRONS • Urine enters the hollow area of the kidney called the RENAL PELVIS • Urine passes through the URETERS • Urine gets stored in the URINARY BLADDER where the SPHINCTER muscles CONTROL when urine is expelled through the URETHRA.

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