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A transformation in X-ray technology:
3D X-ray made truly portable
Mar 7th 2016
Mark Evans, CEO
mark.evans@adaptiximaging....
Field Emitters from
Field Emission Electric
Propulsion (FEEP)
- used in satellite
propulsion
X-ray Optics
- used in
X-ray ...
Vacuum tubes have been superseded in most
arenas…but not in medical imaging
So the X-ray Detector and IT infrastructure has
gone digital…but the source has not…yet.
• No 3D capability
• No quantific...
• “Movement free” 3D
• Quantification
• Far lower dose than CT
• True portability
• Lower purchase and maintenance costs
•...
1. Medical [Focus]
• All: $16.9bn [2020]
• CAGR = 4.7% [2013- 2018]
• Portable: $8.4bn [2020]
+ >20 mid-tier
2. Dental [Se...
TREND DRIVER
Digital/Solid State Reducing cost and enhancing maintenance economics.
3D Imaging Enhancing the ability to di...
“1.5-2.0% of all cancers in the United States may
be attributable to the radiation from CT studies.”
[1] www.nejm.org/doi/...
Tomosynthesis >50% of Breast imaging market
and is emerging in General Radiology.
We will make low-dose 3D imaging available at
the bedside, GP clinic or in an ambulance.
Moving the point of diagnosis giv...
Portable
Planar X-ray
Planar Array Digital
Tomosynthesis
128 slice Computed
Tomography (CT)
3D Capability NO YES YES
Appro...
Prototype housing and
manufacturing design
concepts complete.
Scale prototype on track for Q1 2016 will
demonstrate full p...
1. Hospital (Entry Mkt)
• Taking a patient from ICU to the
imaging suite takes 30 minutes for
1xDoctor + 1xNurse + 1xPorte...
Objectives
Seed •Scale hardware prototype.
•Reconstruction software developed to Alpha.
•Manufacturing agreements in place...
A transformation in X-ray technology:
3D X-ray made truly portable
Mar 7th 2016
Mark Evans, CEO
mark.evans@adaptiximaging....
Mark Evans - Adaptix - UK - Stanford Engineering - Mar 7 2016
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Mark Evans - Adaptix - UK - Stanford Engineering - Mar 7 2016

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Talk by Mark Evans, CEO, Adaptix Imaging Ltd (UK), at Stanford on March 7 2016, in our session: 'From Comets to Startups :: Building Europe's SpaceTech Entrepreneurship Ecosystem'.

Website: http://www.StanfordEuropreneurs.org
YouTube Channel: https://www.youtube.com/user/StanfordEuropreneurs
Twitter: @Europreneurs

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Mark Evans - Adaptix - UK - Stanford Engineering - Mar 7 2016

  1. 1. A transformation in X-ray technology: 3D X-ray made truly portable Mar 7th 2016 Mark Evans, CEO mark.evans@adaptiximaging.com @adaptiximaging www.adaptiximaging.com European Entrepreneurship Stanford Engineering
  2. 2. Field Emitters from Field Emission Electric Propulsion (FEEP) - used in satellite propulsion X-ray Optics - used in X-ray telescopes Image reconstruction approaches used in Earth Observation Disrupting the >$17bn medical imaging industry using space origin technology.
  3. 3. Vacuum tubes have been superseded in most arenas…but not in medical imaging
  4. 4. So the X-ray Detector and IT infrastructure has gone digital…but the source has not…yet. • No 3D capability • No quantification capability • Big and bulky • Large power need • Expensive technology
  5. 5. • “Movement free” 3D • Quantification • Far lower dose than CT • True portability • Lower purchase and maintenance costs • Reduced power need (normal ring main) Our innovation: A pixilated Flat Panel X-ray Source (FPS) that completes digitization.
  6. 6. 1. Medical [Focus] • All: $16.9bn [2020] • CAGR = 4.7% [2013- 2018] • Portable: $8.4bn [2020] + >20 mid-tier 2. Dental [Secondary] • All: $2.7bn [2019] • CAGR = 9.7% [2014 to 2019] • 3D is highest growth segment 3. Industrial [License] • All: $652m [2020] • CAGR = 6% 4. Security [License] • All: $2.6bn [2020] • CAGR = 7%
  7. 7. TREND DRIVER Digital/Solid State Reducing cost and enhancing maintenance economics. 3D Imaging Enhancing the ability to diagnose. Portable Taking imaging to the patient to reduce total costs. Lower Dose Imaging is more prevalent, increasing aggregate risk. Screening Allowing early intervention to reduce cost-to-treat. Quantification Ascertaining disease progression and response to therapy. Digital Tomosynthesis (DT) Obtaining 3D imaging without the cost of a CT scanner. A series of long-term trends in diagnostic imaging are driving the market.
  8. 8. “1.5-2.0% of all cancers in the United States may be attributable to the radiation from CT studies.” [1] www.nejm.org/doi/full/10.1056/NEJMra072149
  9. 9. Tomosynthesis >50% of Breast imaging market and is emerging in General Radiology.
  10. 10. We will make low-dose 3D imaging available at the bedside, GP clinic or in an ambulance. Moving the point of diagnosis gives clinical and economic advantages.
  11. 11. Portable Planar X-ray Planar Array Digital Tomosynthesis 128 slice Computed Tomography (CT) 3D Capability NO YES YES Approximate Size Filing Cabinet Carry-on bag Small Car Typical Dose (CXR) 0.10 mSv <0.13 mSv 1.5-8.00 mSv Typical Cost $170,000 $100,000 $1,100,000 Cost per scan $35 <$35 $330 Typical Weight 200kg 20kg 2,000kg Our USP is low-dose low-cost portable 3D.
  12. 12. Prototype housing and manufacturing design concepts complete. Scale prototype on track for Q1 2016 will demonstrate full performance. Image reconstruction approach developed. Test Devices are emitting X-ray.
  13. 13. 1. Hospital (Entry Mkt) • Taking a patient from ICU to the imaging suite takes 30 minutes for 1xDoctor + 1xNurse + 1xPorter. 2. Primary Care • X-ray initial diagnostic for chest: Lung Cancer, COPD, CHF. • Use of 3D imaging can reduce need for CT by up to 75% due to reduction in inconclusive reads. 3. Developing World • Low-cost low-dose DT can reduce need for high-cost high-dose CT. • ‘Solid state’ reduces need for trained maintenance technicians and a barrier for deployment. 4. Lung Screening • >10m US smokers should be screened annually. Up to 60% will have abnormalities. • Reducing screening cost from $330 to $35 will impact viability.
  14. 14. Objectives Seed •Scale hardware prototype. •Reconstruction software developed to Alpha. •Manufacturing agreements in place. A •Regulated product ready for commercial production. •Clinical Trial: Q4 2016 •Manufacturing and Commercial channels ready. Growth •Working Capital for commercial production. •Material revenues commence: Jun 2017 •Target: > $100m run-rate < 3 years from launch. Looking for US investors to assist a ‘flip’ in to becoming a US company to drive exit value.
  15. 15. A transformation in X-ray technology: 3D X-ray made truly portable Mar 7th 2016 Mark Evans, CEO mark.evans@adaptiximaging.com @adaptiximaging www.adaptiximaging.com European Entrepreneurship Stanford Engineering

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