Successfully reported this slideshow.
We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. You can change your ad preferences anytime.

Blood glucose regulation


Published on

  • Be the first to comment

Blood glucose regulation

  1. 1. Blood glucose regulation Dr. Sadaf Mumtaz 14/02/11
  2. 2. <ul><li>Insulin is associated with energy abundance </li></ul><ul><li>Unbound form </li></ul>
  3. 3. Liver phosphorylase glucokinase Glycogen synthase Liver cells Phosphorylase & Glucose phosphatase
  4. 4. Glucose transporters ER Ca 2+ IP3 Glut 4 receptor Agonist Ca 2+ Glucose Tyrosine kinase
  5. 5. Fat metabolism Glucose Pyruvate Acetyl CoA Citrate, isocitrate ions Acetyl CoA carboxylase Acetyl CoA Malonyl-CoA Triglycerides Lipoprotein lipase Fatty acids Hormone sensitive lipase Α -glycerol phosphate
  6. 6. Ketosis
  7. 7. Protein metabolism
  8. 8. Mechanism of insulin secretion Sulphonylurea drugs
  9. 9. Glucagon <ul><li>Glycogenolysis </li></ul><ul><li>Gluconeogenesis </li></ul>
  10. 10. <ul><li>Adrenal diabetes </li></ul><ul><li>Pituitary diabetes </li></ul><ul><li>Gestational diabetes </li></ul>
  11. 11. Thanks Volunteers for OGTT