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Mirenor. NMR Non-invasive Glucometer.


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Non-invasive glucometer based on NMR spectrometer.
We create a non-invasive glucose monitor that works on the wrist and makes measurements every 30 seconds.

Published in: Healthcare
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Mirenor. NMR Non-invasive Glucometer.

  1. 1. NMR Non-invasive Glucometer
  2. 2. Non-invasive glucometer based on NMR spectrometer 1/11 people ill with diabetes On the materials International Diabetes Federation (IDF) Diabetes in the world 420 million patients with diabetes mellitus in the world - 415 million in 2015 - 642 million by 2040 The number of children with type 1 diabetes exceeded 500,000
  3. 3. Control of blood sugar for diabetics is a daily, repeated and extremely unpleasant procedure. Every day people with diabetes are forced to use a glucometer - a device for monitoring blood glucose level. Almost all types of modern glucometers require human skin puncture.
  4. 4. Our goal Creating a non-invasive glucose monitor that works on the wrist and makes measurements every 30 seconds. The operation of the device is based on the phenomenon of nuclear magnetic resonance (NMR).
  5. 5. Nuclear magnetic resonance (NMR) NMR spectroscopy - analytical method for studying chemical which uses the phenomenon of nuclear magnetic resonance (NMR) NMR spectrometer provides data on the molecular structure of chemical substances. These features make NMR spectroscopy a convenient tool for analyzing the composition of human blood.
  6. 6. Why the NMR? The NMR measurement method makes it possible to determine all organic substances, both qualitatively and quantitatively. At the moment, NMR is the best method of chemical and biological analysis.
  7. 7. How does it work NMR is a very sensitive magnetic field meter for organic molecules that make up the blood plasma. And technically, NMR is a magnetic system and a low-power transceiver.
  8. 8. Surface NMR bio-sensor MIRENOR ● Used Halbach array of permanent magnets as a way to obtain a powerful and homogeneous magnetic field ● The impulse method allows you to get results in a few seconds after the measurement cycle ● The method of markers allows you to make measurements of glucose in the blood relative to a constant container with a known substance ● A marker of maleic acid or a marker of tetramethylsilane (TMS) allows to eliminate measurement errors at the hardware level
  9. 9. Progress of work 2014-2017 years By working out possible methods of performing TK, three methods of analysis were tested: ● Method for determining the optical angles of the polarization of glucose in a pulsed magnetic field (the Faraday effect was used) ● Speckle-interferometry. ● Nuclear magnetic resonance. The NMR method showed the best results and, despite a lot of technical problems, was chosen as the main one. Further, all the work was done only in the direction of NMR.
  10. 10. 2017 Despite technical difficulties, we consider the development of NMR as a non-invasive glucometer an achievable task. This device will make the life of people with diabetes more comfortable. We are ready to make every effort to achieve this goal.