NCCTG - Buckner

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  • Added to series 11-21-2002 JS
  • Revised 7-8-2002 BB Estes,S; Revised 11-13-2002 MN; Revised 11-21-2002 JS
  • Dr. Harold Freeman; Director of the Center to Reduce Health Disparities, NCI and Ralph Lauren Center for Cancer Control and Prevention, Harlem Hospital
  • NCCTG - Buckner

    1. 1. 1 What is NCCTG?What is NCCTG? North Central Cancer Treatment GroupNorth Central Cancer Treatment Group Jan C. Buckner, MDJan C. Buckner, MD Group ChairGroup Chair June 17, 2003June 17, 2003
    2. 2. 2 PurposePurpose • To improve duration and qualityTo improve duration and quality of life by performing high qualityof life by performing high quality clinical trials in the communityclinical trials in the community settingsetting • To improve understanding ofTo improve understanding of cancer biology and biologicalcancer biology and biological consequences of treatmentconsequences of treatment • To improve methodology forTo improve methodology for conducting clinical trialsconducting clinical trials
    3. 3. 3 NCCTG DistinctivesNCCTG Distinctives • Community-basedCommunity-based • Single Research BaseSingle Research Base • Intertwined with MCCC and MayoIntertwined with MCCC and Mayo FoundationFoundation
    4. 4. 4 OrganizationOrganization • MembersMembers • GovernanceGovernance • MayoMayo • Administrative InfrastructureAdministrative Infrastructure • Scientific ExpertiseScientific Expertise
    5. 5. 5 FundingFunding • NCINCI • MayoMayo • ContractsContracts • MembersMembers • PhilanthropyPhilanthropy
    6. 6. 6 Criteria for MembershipCriteria for Membership • AccrualAccrual • Data quality and timelinessData quality and timeliness
    7. 7. 7 Categories of MembershipCategories of Membership • CCOPCCOP • ConsortiumConsortium • AffiliateAffiliate
    8. 8. 8 ParticipantsParticipants • 1247 physicians1247 physicians • 424 sites424 sites June 16, 2003
    9. 9. CP1041821-2 AKAK WAWA OROR IDID MTMT SaskatchewanSaskatchewan WYWY UTUTNVNV CACA AZAZ NMNM COCO NENE SDSD NDND MNMN MOMOKSKS FLFL NCNC MIMI KYKY OHOH WVWV VAVA PAPA NYNY MDMD DEDE NJNJ CTCT RIRI MAMA MEME NHNHVTVT IAIA ILIL WIWI OntarioOntario DCDC HIHI MexicoMexico GAGA TXTX LALA ARAR ALAL TNTN MSMS OKOK SCSC ININ
    10. 10. CP1041821-1 AKAK WAWA OROR IDID MTMT SaskatchewanSaskatchewan WYWY UTUTNVNV CACA AZAZ NMNM COCO NENE SDSD NDND MNMN MOMOKSKS FLFL NCNC MIMI KYKY OHOH WVWV VAVA PAPA NYNY MDMD DEDE NJNJ CTCT RIRI MAMA MEME NHNHVTVT IAIA 1717 2222 55 77 22 33 ILIL WIWI OntarioOntario DCDC 99 2828 2929 55 1919 6161 33 11 3737 3030 11 11 2 HIHI MexicoMexico 11 GAGA 88 TXTX LALA ARAR ALAL TNTN MSMS OKOK 22 77 1010 11 1010 SCSC11 ININ 1
    11. 11. 11 What are our researchWhat are our research components?components?
    12. 12. 12 Funded ProgramsFunded Programs • BrainBrain • BreastBreast • GIGI • LungLung • Cancer ControlCancer Control
    13. 13. 13 Working GroupsWorking Groups • MelanomaMelanoma • ProstateProstate • HematologyHematology
    14. 14. 14 Discipline-OrientedDiscipline-Oriented CommitteesCommittees • Novel TherapeuticsNovel Therapeutics • Quality of LifeQuality of Life • Gender and Ethnic DiversityGender and Ethnic Diversity • Patient AdvocacyPatient Advocacy
    15. 15. 15 Modality CommitteesModality Committees • Medical OncologyMedical Oncology • PathologyPathology • Biospecimen RepositoryBiospecimen Repository • Radiation OncologyRadiation Oncology • SurgerySurgery
    16. 16. 16 Core Support ServicesCore Support Services • BiostatisticsBiostatistics • InformaticsInformatics • Data ManagementData Management • AuditAudit • Operations OfficeOperations Office • CommunicationsCommunications • Data Monitoring CommitteeData Monitoring Committee
    17. 17. 17 Who are our Mayo ClinicWho are our Mayo Clinic investigators?investigators?
    18. 18. 18 Mayo Clinic MD’s and PhD’sMayo Clinic MD’s and PhD’s Participating in NCCTGParticipating in NCCTG 247 27 31 305 0 50 100 150 200 250 300 350 Rochester Jacksonville Scottsdale TOTAL June 16, 2003
    19. 19. 19 Departments/DivisionsDepartments/Divisions RepresentedRepresented 40 8 8 0 5 10 15 20 25 30 35 40 Rochester Jacksonville Scottsdale July, 2001
    20. 20. 20 Departments/Divisions/ProgramsDepartments/Divisions/Programs A-MA-M • Anesthesiology • Area Medicine • Biochemistry and Molecular Biology • Cardiovascular Diseases • Clinical Epidemiology • Dermatology • Endocrinology • Gastroenterology and Hepatology • General Internal Medicine • Hematology • Health Sciences Research • Laboratory Medicine and Pathology • Medical Genetics • Molecular Genetics • Molecular Medicine Program July, 2001
    21. 21. 21 Departments/Divisions/ProgramsDepartments/Divisions/Programs N-ZN-Z • Neurologic Surgery • Neurology • Nicotine Dependence Center • Nuclear Medicine • Obstetrics and Gynecology • Oncology • Physical Medicine and Rehabilitation • Psychiatry and Psychology • Pulmonary and Critical Care Medicine • Radiation Oncology • Radiology • Surgery • Transplant Center • Urology July, 2001
    22. 22. 22 What is our productivity?What is our productivity?
    23. 23. 23 Protocol ActivityProtocol Activity Cancer Treatment and ControlCancer Treatment and Control • HistoricalHistorical • 384 over 25 years384 over 25 years • Currently activeCurrently active • 50 open50 open • 235 closed with follow up taking235 closed with follow up taking placeplace • Currently in developmentCurrently in development • 3737 June 13, 2003
    24. 24. 24 Patient AccrualPatient Accrual Cancer Treatment and ControlCancer Treatment and Control (58,537 over 25 years)(58,537 over 25 years) 3,010 4,684 4,870 0 500 1,000 1,500 2,000 2,500 3,000 3,500 4,000 4,500 5,000 2000 2001 2002 June 13, 2003
    25. 25. 25 Tissue SpecimensTissue Specimens (10,334 over 25 years)(10,334 over 25 years) 755 775 938 0 100 200 300 400 500 600 700 800 900 1,000 2000 2001 2002 June 13, 2003
    26. 26. 26 NCCTG PublicationsNCCTG Publications 2000-2002 Journals2000-2002 Journals • Am J Clin Oncol • Br J Haematol • Cancer • Cancer Invest • Clinical Cancer Research • Current Oncology Reports • Int J Gynaecol Obstet • Int J Radiat Oncol Biol Phys • Invest New Drugs • J Clin Oncol • J Neurooncol • J Neurosurg • J Natl Cancer Inst • JAMA • Lancet • Leukemia • Lung Cancer • Meta-Analysis • N Engl J Med • Oncology • Oncol Nurs Forum • Semin Oncol • Stat Med • Support Care Cancer
    27. 27. 27 What are the educationWhat are the education components?components?
    28. 28. 28 Target AudiencesTarget Audiences • PhysiciansPhysicians • NursesNurses • CRA’sCRA’s • Patient AdvocatesPatient Advocates
    29. 29. 29 Educational SymposiaEducational Symposia TopicsTopics • New Directions in Oncologic ImagingNew Directions in Oncologic Imaging • Colorectal Cancer: RevisingColorectal Cancer: Revising Standards/Evolving TreatmentsStandards/Evolving Treatments • Breast Cancer Management: CurrentBreast Cancer Management: Current Status and Future Research DirectionsStatus and Future Research Directions • Molecular Markers: Current OncologicMolecular Markers: Current Oncologic ApplicationApplication • Melanoma in the 21st CenturyMelanoma in the 21st Century • AJCC Staging of Breast/Colon CancerAJCC Staging of Breast/Colon Cancer June, 2003
    30. 30. 30 Education SymposiaEducation Symposia Visiting LecturersVisiting Lecturers • NR DunnickNR Dunnick University of MichiganUniversity of Michigan • RJ MayerRJ Mayer Dana FarberDana Farber • NJ MeropolNJ Meropol Fox ChaseFox Chase • AP VenookAP Venook University of CaliforniaUniversity of California • GN HortobagyiGN Hortobagyi MD AndersonMD Anderson • HL McLeodHL McLeod Washington UniversityWashington University • CM BalchCM Balch ASCOASCO • H FreemanH Freeman NCI; Harlem HospitalNCI; Harlem Hospital
    31. 31. 31 Nurses and CRAsNurses and CRAs • Semi-annual symposiaSemi-annual symposia • Specific Disease FocusSpecific Disease Focus • CAMCAM • Special PopulationsSpecial Populations • CRA Training WorkshopsCRA Training Workshops • Skills FairSkills Fair • SOCRA certificationSOCRA certification • Double enrollmentDouble enrollment
    32. 32. 32 Patient AdvocatesPatient Advocates • Coalition modulesCoalition modules • Clinical trial components and conductClinical trial components and conduct • Semi-annual meetingsSemi-annual meetings • Dinner speakers/guestsDinner speakers/guests • Committee businessCommittee business • Research committee participationResearch committee participation • Spring Symposium 2003Spring Symposium 2003
    33. 33. 33 VisionVision • GrowthGrowth • Financial securityFinancial security • CollaborationCollaboration
    34. 34. 34 GrowthGrowth • AccrualAccrual • Scientific ProgramsScientific Programs • BreadthBreadth • DepthDepth • New ProgramsNew Programs • MelanomaMelanoma • MembershipMembership
    35. 35. 35 Financial SecurityFinancial Security • Prudent managementPrudent management • Ancillary grants/contractsAncillary grants/contracts • Industry partnershipIndustry partnership
    36. 36. 36 CollaborationCollaboration • Mayo Clinic Cancer CenterMayo Clinic Cancer Center • Cooperative Groups/CoalitionCooperative Groups/Coalition • Academic institutionsAcademic institutions • IndustryIndustry
    37. 37. 37 PurposePurpose

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